Garg Research Group

Natural Product Synthesis & Reaction Discovery


Research in the Garg Laboratory is directed toward the development of synthetic strategies and methods that enable the synthesis of complex bioactive molecules.  

Our methodological interests lie primarily in the three main areas:

  1. (a) transition-metal catalyzed cross-coupling reactions of unconventional electrophiles,
    such as esters and amides, using non-precious metal catalysis, and bench stable preparations of catalysts (see TCI website).

  1. (b)new tactics to synthesize functionalized heterocycles, including ‘interrupted Fischer
    indolization’ cascades and the manipulation of cyclic alkynes and allenes (see Aldrich Professor Portal).

(c) total synthesis of complex small molecules, such as drugs and natural products.

We also enjoy the opportunity to collaborate in areas such as natural product biosynthesis, green chemistry, solar cell technologies, and studies of fundamental reactivity.  

Check out the scrolling images above to get a glimpse of some of our current research efforts!