207. How do ALS-associated mutations in Superoxide Dismutase 1 promote aggregation of the protein? Shaw, B. F.; Valentine, J. S. Trends in Biochem. Sci., 2007, 32(2), 78-85.

206. Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Ferri, A., Cozzolino, M., Crosio, C., Nencini, M., Casciati, A., Gralla, E.B., Rotilli, G., Valentine, J.S., Carri, M.T. Proc. Natl. Acad. Sci., 2006, 103 (37), 13860-13865.

205. Local unfolding in a destabilized, Pathogenic Variant of Superoxide Dismuase 1 observed with H/D exchange and mass spectrometry. Shaw, B.F., Durazo, A., Nersissian, A.M., Whitelegge, J.P., Faull, K.F. J. Biol. Chem., 2006, 286 (26) 18167-18176.

204. Superoxide dismutase 1 modulates expression of transferrin receptor. Danzeisen, R., Achsel, T.; Bederke, U., Cozzolino, M., Crosio, C., Ferri, A., Frenzel,M., Gralla, E.B., Huber, L., Ludolph, A., Nencini, M., Rotilio, G., Valentine, J.S., Carri, M.T. J. Bio. Chem., 2006, 11(4), 489-498.

203. Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-isolated Wild-type Enzymes. Strange, R.W., Antonyuk, S.V., Hough, M.A., Doucette, P.A., Valentine, J.S., Hasnain, S.S.. J. Mol. Biol., 2006, 356(5), 1152-1162.

202. Metal-deficient copper-zinc superoxide dismutase and familial amyotrophic lateral sclerosis: Pathogenic SOD1 oligomerization through non-native protein-protein interactions. Hart, P. J, Valentine, J.S. ACS Symposium Series, 2005, No. 903 (Medicinal Inorganic Chemistry), 348-365.

201. Fully Metallated S134N Cu,Zn-Superoxide Dismutase Displays Abnormal Mobility and Intermolecular Contacts in Solution. Banci, L., Bertini, I., D'Amelio, N.; Gaggelli, E., Libralesso, E., Matecko, I., Turano, P., Valentine, J.S. J. Biol. Chem., 2005, 280(43), 35815-35821.

200. Exogenous manganous ion at millimolar levels rescues all known dioxygen-sensitive phenotypes of yeast lacking CuZnSOD. Sanchez, R. J., Srinivasan, C., Munroe, W. H., Wallace, M. A., Martins, J., Kao, T. Y., Le, K.; Gralla, E. B., Valentine, J. S. J. Biol. Chem., 2005, 10(8), 913-923.

199. Copper-Zinc Superoxide Dismutase and Amyotrophic Lateral Sclerosis. Valentine, J. S., Doucette, P. A., Potter, S. Z. Ann. Rev. Biochem., 2005, 74, 563-93.

198. Induction of Phenotypes Resembling CuZn-Superoxide Dismutase Deletion in Wild-Type Yeast Cells: An in vivo Assay for Role of Superoxide in the Toxicity of Redox-Cycling Compounds. Wallace, M. A., Bailey, S., Fukuto, J. M., Valentine, J.S., Gralla, E.B. Chem. Res. Toxicology, 2005, 18, 1279-1286.

197. Destabilization of Apoprotein is Insufficient to Explain Cu,Zn-Superoxide Dismutase-linked ALS Pathogenesis. Rodriguez, J.A., Shaw, B. F., Durazo, A., Sohn, S. H., Doucette, P. A., Nersissian, A.M., Faull, K. F., Eggers, D.K., Tiwari, A., Hayward, L.J., Valentine J.S. Proc. Natl. Acad. Sci., 2005, 102, 10516-10521.

196. Structural Consequences of the Familial Amyotrophic Lateral Sclerosis SOD1 Mutant His46Arg. Antonyuk, S, Elam, J. S., Hough, M. A., Strange, R. W., Doucette, P. A., Rodriguez, J. A., Hayward, L.J., Valentine, J. S., Hart, P. J., Hasnain, S. S., Prot. Sci., 2005, 14, 1201-1213.

195. Dissociation of Human Copper-Zinc Superoxide Dismutase Dimers Using Chaotrope and Reductant: Insights Into the Molecular Basis for Diner Stability. Doucette, P. A.; Whitson, L. J.; Cao, X.; Schirf, V.; Demeler, B.; Valentine, J. S.; Hansen, J. C.; Hart, P. J., J. Biol. Chem., 2004, 279, 54558-54566.

194. Local Nanomechanical Motion of the Cell Wall of Saccharomyces cerevisiae. Pelling, A. E.; Sehati, S.; Gralla, E. B.; Valentine, J. S.; Gimzewski, J. K. Science, 2004, 305, 1147-1150.

193. Superoxide Inhibits 4Fe-4S Cluster Enzymes Involved in Amino Acid Biosynthesis: Cross-Compartment Protection by CuZn-Superoxide Dismutase. Wallace, M. A.; Liou, L.-L.; Martins, J.; Clement, M. H. S.; Bailey, S.; Longo, V. D.; Valentine, J. S.; Gralla, E. B., J. Biol. Chem. 2004, 279, 32055-32062.

192. Mutations in Saccharomyces cerevisiae Iron Sulfur Cluster Assembly Genes and Oxidative Stress Relevant to Cu/Zn Superoxide Dismutase. Jensen, L. T., Sanchez, R. J., Srinivasan, C., Valentine, J. S., and Culotta, V. C. J. Biol. Chem. 2004, 279, 29938-29943.

191. Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants. Hough, M. A.; Grossman, J. G.; Antonyuk, S. V.; Strange, R. W.; Doucette, P. A.; Rodriguez, J. A.; Whitson, L. J.; Hart, P. J.; Hayward, L.J.; Valentine, J.S.; Hasnain, S.S. Proc. Natl. Acad. Sci. USA, 2004, 101, 5976-5981.

190. Mechanisms for Activating Cu- and Zn-Containing Superoxide Dismutase in the Absence of the CCS Cu Chaperone. Carroll, M. C.; Girouard, J. B.; Ulloa, J. L.; Subramaniam, J. R.; Wong, P. C.; Valentine, J. S.; Culotta, V.C. Proc. Natl. Acad. Sci. USA, 2004, 101, 5964-5969.

189. SOD2 Functions Downstream of Sch9 to Extend Longevity in Yeast. Fabrizio, Paola; Liou, Lee-Loung; Moy, V. N.; Diaspro, A.; Valentine, J. S.; Gralla, E. B.; Longo, V. D. Genetics, 2003, 163, 35-46.

188. Dynamic Properties of the G93A Mutant of Copper-Zinc Superoxide Dismutase as Detected by NMR Spectroscopy: Implications for the Pathology of Familial Amyotrophic Lateral Sclerosis. Shipp, E. L.; Cantini, F.; Bertini, I.; Valentine, J. S.; Banci, L. Biochemistry, 2003, 42, 1890-1899.

187. An Alternative Mechanism of Bicarbonate-Mediated Peroxidation by Copper-Zinc Superoxide Dismutase: Rates Enhanced via Proposed Enzyme-Associated Peroxicarbonate Intermediate. Elam, J. S.; Malek, K.; Rodriguez, J. A.; Doucette, P. A.; Taylor, A. B.; Hayward, L. J.; Cabelli, D. E.; Valentine, J. S.; Hart, P. John. J. Biol. Chem., 2003, 278, 21032-21039.

186. Spectroscopic Investigation of Stellacyanin Mutants: Axial Ligand Interactions at the Blue Copper Site. DeBeer George, S.; Basumallick, L.; Szilagyi, R. K.; Randall, D. W.; Hill, Michael G.; Nersissian, A. M.; Valentine, J. S.; Hedman, B.; Hodgson, K. O.; Solomon, E. I., J. Am. Chem. Soc., 2003, 125, 11314-11328.

185. Manganese. Valentine, J. S. Chem & Engr News, 2003, 81, 76.

184. Amyloid-Like Filaments and Water-Filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS. Elam, J. S.; Taylor, A. B.; Strange, R.; Antonyuk, S.; Doucette, P. A.; Rodriguez, J. A.; Hasnain, S. S.; Hayward, L. J.; Valentine, J. S.; Yeates, T. O.; Hart, P. J. Nat. Struct. Biol., 2003, 10, 461-467.

183. The Structure of Holo and Metal-Deficient Wild-Type Human Cu, Zn Superoxide Dismutase and its Relevance to Familial Amyotrophic Lateral Sclerosis. Strange, R. W.; Antonyuk, S.; Hough, M. A.; Doucette, P. A.; Rodriguez, J. A.; Hart, P. J.; Hayward, L. J.; Valentine, J. S.; Hasnain, S. S.. J. Mol. Biol. 2003, 328, 877-891.

182. The Perplexing Role of Copper-Zinc Superoxide Dismutase in Amyotrophic Lateral Sclerosis (Lou Gehrig's disease). Potter, S. Z.; Valentine, J. S., J. Biol. Inorg. Chem., 2003, 8, 373-380.

181. Misfolded CuZnSOD and Amyotrophic Lateral Sclerosis. Valentine, J.S. , Hart, P.J. Proc. Natl. Acad. Sci. U.S.A., 2003, 100, 3617-3622.

180. Do Oxidatively Modified Proteins Cause ALS? Valentine, J.S., Free Rad. Biol. Med., 2002, 33, 1314-1320.

179. On the Chemical Properties of the Transient Complexes LmMn-1-OOR, part 2. The case of (2,3,9,10-tetramethyl-1,4,8,11-tetraazacyclotetradeca-1,3,8,10-tetraene)(H₂O)CoIII-OOR²⁺ (R = CH₂OH, CH₂CN, CCl₃) and Reactions with the Methylperoxyl Radical. Solomon-Rapaport, E.; Masarwa, A.; Cohen, H.; Valentine, J. S.; Meyerstein, D. Eur. J. Inorg. Chem. 2002, 2427-2432.

178. Familial Amyotrophic Lateral Sclerosis-Associated Mutations Decrease the Thermal Stability of Distinctly Metallated Species of Human Copper-Zinc Superoxide Dismutase. Rodriguez, J. A.; Valentine, J. S.; Eggers, D. K.; Roe, J. A.; Tiwari, A.; Brown, R. H., Jr.; Hayward, L. J. J. Biol. Chem., 2002, 277, 15932-15937.

177. Decreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis. Hayward, L. J.; Rodriguez, J. A.; Kim, J. W.; Tiwari, A.; Goto, J. J.; Cabelli, D. E.; Valentine, .J S.; Brown, Robert H., Jr. J. .Biol. Chem., 2002, 277, 15923-15931.

176. Crowding and Hydration Effects on Protein Conformation: A Study with Sol-Gel Encapsulated Proteins, Eggers, D. K.; Valentine, J. S., J. Mol. Biol., 2001, 314, 911-922.

175. Molecular confinement influences protein structure and enhances thermal protein stability. Eggers, D.K. and Valentine, J.S. Protein Science, 2001, 10:250-261.

174. Stellacyanin, a Member of the Phytocyanin Family of Plant Proteins. Aram Migran Nersissian, P. J. Hart, J. S. Valentine in Handbook of Metalloproteins, Wieghardt, K.; Huber, R.; Poulos, T.; Messerschmidt, A., eds; John Wiley & Sons, Ltd.: London, 2001.

173. In Vivo Peroxidative Activity of Fals-Mutant Human CuZnSODs Expressed in Yeast. Roe, J.A.; Wiedau-Pazos, M.; Moy, V.N.; Goto, J.J.; Gralla, E.B.; Valentine, J.S., Free Radical Biology & Medicine, 2002, 32, 169-174.

172. Evidence for a Novel Role of Copper-Zinc Superoxide Dismutase in Zinc Metabolism. Wei, J-P. J.; Srinivasan, C.; Han, H.; Valentine, J.S.; Gralla, E.B., J. Biol. Chem., 2001, 276, 44798-44803.

171. Copper (2+) Binding to the Surface Residue Cysteine 111 of His46Arg Human Copper-Zinc Superoxide Dismutase, a Familial Amyotrophic Lateral Sclerosis Mutant. Liu, H.; Zhu, H.; Eggers, D. K.; Nersissian, A. M.; Faull, K. F.; Goto, J. J.; Ai, J.; Sanders-Loehr, J.; Gralla, E. B.; Valentine, J. S., Biochemistry, 2000, 39, 8125-8132.

170. Effects of Nitric Oxide on the Copper –Responsive Transcription Factor Ace1 in Saccyaromyces cerevisiae: Cytotoxic and Cytoprotective Actions of Nitric Oxide. Chiang, K. T.; Shinyashiki, M.; Switzer, C. H.; Valentine, J. S.; Gralla, E. B.; Thiele, D. J.; Fukuto, J. M.; Arch. Biochem. Biophys., 2000, 377, 296-303.

169. X-ray Absorption Edge and EXAFS Studies of the Blue Copper Site in Stellacyanin: Effects of Axial Amide Coordination. DeBeer, S.; Randall, D. W.; Nersissian, A. M.; Valentine, J. S.; Hedman, B.; Hodgson, K. O.; Solomon, E. I., J. Phys. Chem B., 2000, 104, 46.

168. Yeast Lacking Superoxide Dismutase(s) Show Elevated Levels of "Free Iron" as Measured by Whole Cell Electron Paramagnetic Resonance. Srinivasan, S.; Liba, A.; Imlay, J. A.; Valentine, J. S.; Gralla, E. B., J. Biol. Chem., 2000, 275, 29187-29192.

167. Models of Superoxide Dismutases. Cabelli, D. E.; Riley, D.; Rodriguez, J. A.; Valentine, J. S.; Zhu, H. in Biomimetic Oxidations Catalyzed by Transition Metal Complexes, Meunier, B., ed.; Imperial College Press: 1999, pp. 461-508.

166. Yeast Lacking Cu-Zn Superoxide Dismutase Show Altered Iron Homeostasis: Role of Oxidative Stress in Iron Metabolism. De Freitas, J. M.; Liba, A.; Meneghini , R.; Valentine, J. S.; Gralla, E. B., J. Biol. Chem., 2000, 275, 11645-11649.

165. Cobalt(2+) Binding to Human and Tomato Copper Chaperone for Superoxide Dismutase: Implications for the Metal Ion Transfer Mechanism. Zhu, H.; Shipp, E.; Sanchez, R. J.; Liba, A.; Stine, J. E.; Hart, P. J.; Gralla, E. B.; Nersissian, A, M.; Valentine, J. S., Biochemistry, 2000, 39, 5413-5421.

164. X-ray Crystallographic and Analytical Ultracentrifugation Analyses of Truncated and Full-Length Yeast Copper Chaperones for SOD (LYS7): A Dimer-Dimer Model of LYS7-SOD Association and Copper Delivery. Hall, L. T.; Sanchez, R. J.; Holloway, S. P.; Zhu, H.; Stine, J. E.; Lyons, T. J.; Demeler, B.; Schirf, V.; Hansen, J. C.; Nersissian, A. M.; Valentine, J. S.; Hart, P. J., Biochemistry, 2000, 39, 3611-3623.

163. The Metal Binding Properties of the Zinc Site of Yeast Copper-Zinc Superoxide Dismutase. Implications for Amyotrophic Lateral Sclerosis. Lyons, T. J.; Nersissian, A. M.; Huang, H.; Yeom, H.; Nishida, C. R.; Graden, J. A.; Gralla, E. B.; Valentine, J. S., J. Biol. Inorg. Chem., 2000, 5, 189-203

162. The Interaction of Nitric Oxide (NO) with the Yeast Transcription Factor Ace1: A Model System for NO-Protein Thiol Interactions with Implications to Metal Metabolism. Shinyashiki, M.; Chiang, K. T.; Switzer, C. H.; Gralla, E. B.; Valentine, J. S.; Thiele, D. J.; Fukuto, J. M., Proc. Natl. Acad. Sci. U.S.A., 2000, 97, 2491-2496.

161. Nucleophilicity of iron-peroxo porphyrin complexes. Wertz, D. L.; Valentine, J. S., Struct. Bonding (Berlin) 2000, 97, 37-60.

160. Loss of In Vitro Metal Ion Binding Specificity in Mutant Copper-Zinc Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis. Goto, J. J.; Zhu, H.; Sanchez, R. J.; Nersissian, A.; Gralla, E. B.; Valentine, J. S.; Cabelli, D. E., J. Biol. Chem., 2000, 275, 1007-1014.

159. Structural Information Through NMR Hyperfine Shifts in Blue Copper Proteins. Ivano Bertini, Claudio O. Fernandez, B. Göran karlsson, Johan Leckner, Claudio Luchinat, Bo G. Malmström, Aram M. Nersissian, Roberta Pieratelli, Eric Shipp, Joan S. Valentine, and Alejandro J. Vila, J. Am. Chem. Soc., 2000, 122, 3701-3707.

158. Mitochondrial Superoxide Decreases Yeast Survival in Stationary Phase. Longo, V. D.; Liou, L. L.; Valentine, J. S.; Gralla, E. B., Arch. Biochem Biophys., 1999, 365, 131-142.

157. Biological Chemistry of Copper-Zinc Superoxide Dismutase and Its Link to Amytrophic Lateral Sclerosis. Lyons, T. J.; Gralla, E. B.; Valentine, J. S. in Metal Ions in Biological Systems, Sigel, A.; Sigel, H., eds; Marcel Dekker, Inc.: New York, 1999, pp. 125-177.

156. Copper-Zinc Superoxide Dismutase and ALS. Valentine, J. S.; Hart, P. J.; Gralla, E. B. in Copper Transport and its Disorders: Molecular and Cellular Aspects, Leone, A.; Mercer, J. F. B., eds; Kluwer Academic: New York, 1999, pp. 193-203.

155. Encapsulation of Proteins in Bulk and Thin Film Sol-Gel Matrices. Dave, B. C.; Miller, J. M.; Dunn, B.; Valentine, J. S.; Zink, J. I., J. Sol-Gel Sci. Technol., 1997, 8, 629-634.

154. Spectroscopic Determination of Cholinesterase Activity and Inhibition in Sol-Gel Media. Akbarian, F.; Lin, A.; Dunn, B. S.; Valentine, J. S.; Zink, J. I., J. Sol-Gel Sci. Technol., 1997, 8, 1067-1070.

153. Synthesis of Sol-Gel Encapsulated Heme Proteins with Chemical Sensing Properties. Lan, E. H.; Dave, B. C.; Fukuto, J. M.; Dunn, B.; Zink, J. I.; Valentine, J. S., J. Mater. Chem., 1999, 9, 45-53.

152. A Structure-Based Mechanism for Copper-Zinc Superoxide Dismutase. Hart, P. J.; Balbirnie, M. M.; Ogihara, N. L.; Nersissian, A. M.; Weiss, M. S.; Valentine, J. S.; Eisenberg, D., Biochemistry, 1999, 38, 2167-2178.

151. Metal Ion Reconstitution Studies of Yeast Copper-Zinc Superoxide Dismutase: The "Phantom" Subunit and the Possible Role of Lys7p. Lyons, T. J.; Nersissian, A.; Goto, J. J.; Zhu, H.; Gralla, E. B.; Valentine, J. S., J. Biol. Inorg. Chem., 1998, 3, 650-662.

149. Sol-Gel Matrices for Protein Entrapment. Dave, B. C.; Dunn, B.; Valentine, J. S.; Zink, J. I. in Immobilized Biomolecules in Analysis, Cass, T.; Ligler, F. S., Eds.; Oxford University Press: New York, 1998, pp. 113-134.

148. Spectroscopic and Geometric Variations in Perturbed Blue Copper Centers: Electronic Structures of Stellacyanin and Cucumber Basic Protein. LaCrioix, L. B.; Randall, D. W.; Nersissian, A. M.; Hoitink, C. W. G.; Canters, G. W.; Valentine, J. S.; Solomon, E. I., J. Am. Chem. Soc., 1998, 120, 9621-9631.

147. Uclacyanins, stellacyanins, and plantacyanins are distinct subfamilies of phytocyanins: Plant-specific mononuclear blue copper proteins. Nersissian, A. M.; Immoos, C.; Hill, M. G.; Hart, P. J.; Williams, G.; Herrmann, R. G.; Valentine, J. S., Prot. Sci, 1998, 7, 1915-1929.

146. Reactions of Copper-Zinc Superoxide Dismutases with Hydrogen Peroxide. Possible Involvement in Familial Amyotrophic Lateral Sclerosis. Valentine, J. S. in Metals and Genetics, Sarkar, B. ed., Plenum Publishing Corp., 1998.

145. Mimicking Cytochrome P-450 2B4 and Aromatase: Aromatization of a Substrate Analogue by a Peroxo Fe(III) Porphyrin Complex. Wertz, D. L.; Sisemore, M. F.; Selke, M.; Driscoll, J.; Valentine, J. S., J. Am. Chem. Soc., 1998, 120, 5331-5332.

144. The Dark Side of Dioxygen Biochemistry. Valentine, J. S.; Wertz, D. L.; Lyons, T. J.; Liou; L. L.; Goto, J. J.; Gralla, E. B., Curr. Opin. Chem. Biol., 1998, 2, 253-262.

143. Subunit Asymmetry in the Three-Dimensional Structure of a Human CuZnSOD Mutant Found in Familial Amyotrophic Lateral Sclerosis. Hart, P. J.; Liu, H.; Pellegrini, M.; Nersissian, A. M.; Gralla, E. B.; Valentine, J. S.; Eisenberg, D., Prot. Sci., 1998, 7, 545-555.

142. Strategies for Encapsulating Biomolecules in Sol-Gel Matrices. Dunn, B.; Miller, J. M.; Dave, B. C.; Valentine, J. S.; Zink, J. I., Acta Mater, 1998, 46, 737-741.

141. Switching on the Nucleophilic Reactivity of a Ferric Porphyrin Peroxo Complex. Selke, M.; Valentine, J. S., J. Am. Chem. Soc., 1998, 120, 2652-2653.

140. Delivering Copper Inside Yeast and Human Cells. Valentine, J. S.; Gralla, E. B., Science, 1997, 278, 817-818.

139. Engineering Metal-Binding Sites in Proteins. Lu, Y; Valentine, J. S., Curr. Opin. Struct. Biol., 1997, 7, 495-500.

138. Do Posttranslational Modifications of CuZnSOD Lead to Sporadic Amyotrophic Lateral Sclerosis? Bredesen, D. E; Ellerby, L. M.; Hart, P. J.; Wiedau-Pazos, M.; Valentine, J. S., Ann. Neurol., 1997, 42, 135-137.

137. Dioxygen Activation by Iron Complexes. The Search for Reactive Intermediates. Selke, M.; Sisemore, M. F.; Ho, R. Y. N; Wertz, D. L.; Valentine, J. S., Journal of Mol. Catal. A: Chem, 1997, 117, 71-82.

136. Metalloporphyrin Peroxo Complexes of Iron (III), Manganese (III), and Titanium (IV). Comparative Studies Demonstrating That the Iron (III) Complex is Extremely Nucleophilic. Sisemore, M. F.; Selke, M.; Burstyn, J. N.; Valentine, J. S., Inorg. Chem, 1997, 36, 979-984.

135. Encapsulation of the Ferritin Protein in Sol-Gel Derived Silica Glasses. Lan, E. H.; Dunn, B.; Valentine, J. S.; Zink, J. I., J. Sol-Gel Sci. and Tech., 1996, 7, 109-116.

134. Nickel Complexes as Antioxidants. Inhibition of Aldehyde Autoxidation by Nickel (II) Tetraazamacrocycles. Nam, W.; Baek, S. J.; Lee, K. A.; Ahn, B. T.; Muller, J. G.; Burrows, C. J.; Valentine, J. S., Inorg. Chem., 1996, 35, 6632-6633.

133. Copper-Zinc Superoxide Dismutase – Why Not pH-Dependent? Ellerby, L. M.; Cabelli, D.E.; Graden, J.A.; Valentine, J.S., J. Am. Chem. Soc., 1996, 118, 6556-6561.

132. Synthesis Conditions for Encapsulating Cytochrome C and Catalase in SiO2 Sol Gel Materials. Miller, J. M.; Dunn, B.; Valentine, J. S.; Zink, J. I., J. Non-Cryst. Solids, 1996, 202, 279-289.

131. Mutations in Copper-Zinc Superoxide Dismutase That Cause Amyotrophic Lateral Sclerosis Alter the Zinc Binding Site and the Redox Behavior of the Protein. Lyons, T. J.; Liu, H.; Goto, J. J.; Nersissian, A. M.; Roe, J. A.; Graden, J. A.; Café, C.; Ellerby, L. M.; Bredesen, D. E.; Gralla, E. B.; Valentine, J. S., Proc. Natl. Acad. Sci. U.S.A., 1996, 93, 12240-12244.

130. Cloning, Expression, and Spectroscopic Characterization of Cucumis sativus Stellacyanin in its Non-glycosylated Form. Nersissian, A. M.; Mehrabian, Z. B.; Nalbandyan, R. M.; Hart, P. J.; Fraczkiewicz, G.; Czernuszewicz, R. S.; Bender, C. J.; Peisach, J.; Herrmann, R. G.; Valentine, J. S., Protein Sci., 1996, 5, 2184-2192.

129. A Missing Link in Cupredoxins: Crystal Structure of Cucumber Stellacyanin at 1.6 Å Resolution. Hart, P. J.; Nersissian, A. M.; Herrmann, R. G.; Nalbandyan, R. M.; Valentine, J. S.; Eisenberg, D. S., Protein Sci., 1996, 5, 2175-2183.

128. Human Bcl-2 Reverses Survival Defects in Yeast Lacking Superoxide Dismutase and Delays Death of Wild Type Yeast. Longo, V. D.; Ellerby, L. M.; Bredesen, D. E.; Valentine, J. S.; Gralla, E. B., J. Cell Biol., 1997, 137, 1581-1588.

127. Cell Death Mechanisms in ALS. Bredesen, D.E.; Wiedau-Pazos, M.; Goto, J.J.; Rabizadeh, S.; Roe, J. A.; Gralla, E. B.; Ellerby, L. M.; Valentine, J. S., Neurology, 1996, 47, 36-39.

126. Autoxidation of Ubiquinol-6 is Independent of Superoxide Dismutase. Schultz, J. R.; Ellerby, L. M.; Gralla, E. B.; Valentine, J. S.; Clarke, C. F. Biochemistry, 1996, 35, 6595-6603.

125. Superoxide Dismutase Activity is Essential for Stationery Phase Survival in Saccharomyces Cerevisiae. Longo, V. D.; Gralla, E. B.; Valentine, J. S. J. Biol. Chem., 1996, 271, 12275-12280.

124. Nanoconfined Proteins and Enzymes: Sol-Gel Based Biomolecular Materials. Dave, B. C.; Dunn B.; Valentine, J. S.; Zink, J. I. Adv. Chem. Ser., 1996, 622, 351-365.

123. Unusual Trigonal-Planar Copper Configuration Revealed in the Atomic Structure of Yeast Copper-Zinc Superoxide Dismutase. Ogihara, N. L.; Parge, H. E.; Hart, P. J.; Weiss, M. S.; Goto, J. J.; Crane, B. R.; Tsang, J.; Slater, K.; Roe, J. A.; Valentine, J. S.; Eisenberg, D.; Tainer, J. A. Biochemistry, 1996, 35, 2316-2321.

122. New Type 2 Copper-Cysteinate Proteins. Copper Site Histidine-to-Cysteine Mutants of Yeast Copper-Zinc Superoxide Dismutase. Lu, Y.; Roe, J.; Bender, C.; Peisach, J.; Banci, L.; Bertini, I.; Gralla, E.; Valentine, J. Inorg. Chem., 1996, 35, 1692-1700.

121. The Diverse Reactivity of Peroxy Ferric Porphyrin Complexes of Electron Rich and Electron Poor Porphyrins. Selke, M.; Sisemore, M. F.; Valentine, J. S. J. Am. Chem. Soc., 1996, 118, 2008-2012.

120. Epoxidation of Electron-Deficient Olefins by a Nucleophilic Iron(III) Peroxo Porphyrinato Complex, Peroxo (tetramesitylporphyrinato) ferrate (1–). Sisemore, M. F.; Burstyn, J. N.; Valentine, J. S. Angew. Chem., 1996, 35, 206-208.

119. Metal Complex-Catalyzed Epoxidation of Olefins by Dioxygen with Co-oxidation of Aldehydes. A Mechanistic Study. Nam, W.; Kim, H. J.; Kim, S. H.; Ho, R. Y. N.; Valentine, J. S.; Inorg. Chem., 1996, 35, 1045-1049.

118. Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis. Wiedau-Pazos, M.; Goto, J. J.; Rabizadeh, S.; Gralla, E. B.; Roe, J. A.; Lee, M. K.; Valentine, J. S.; Bredesen, D. E. Science, 1996, 271, 515-518.

117. Generalities on Metal Ion-Protein Interactions and Their Investigation Techniques. Valentine, J. S. in Handbook of Metal-Ligand Interactions in Biological Fluids, Marcel Dekker, Inc., N.Y. 1995.

116. Biological Reactions of Dioxygen: An Introduction. Ho, R. Y. N.; Liebman, J. F.; Valentine, J. S. in Active Oxygen in Biochemistry, Valentine, J. S.; Foote, C.S.; Greenberg, A.; Liebman, J., eds. Blackie Academic & Professional, Glasgow, 1995.

115. Overview of Energetics and Reactivity of Oxygen. Ho, R.Y.N.; Liebman, J. F.; Valentine, J. S. in Active Oxygen in Chemistry, Foote, C. S.; Valentine, J. S.; Greenberg, A.; Liebman, J., eds. Blackie Academic & Professional, Glasgow, 1995.

114. Nicotinamide Adenine Dinucleotide Phosphate Fluorescence and Absorption Monitoring of Enzymatic Activity in Silicate Sol-Gels for Chemical Sensing Applications. Yamanaka S. A.; Dunn, B.; Valentine, J. S.; Zink, J. I. J. Am. Chem. Soc., 1995, 117, 9095-9096.

113. Synthesis of Protein-Doped Sol-Gel SiO₂ Thin-Films: Evidence for Rotational Mobility of Encapsulated Cytochrome c. Dave, B. C.; Soyez, H.; Miller, J. M.; Dunn, B.; Valentine, J. S.; Zink, J. I. Chem. Mater., 1995, 7, 1431-1434.

112. Optical Sol-Gel Materials Based on Binding and Catalysis by Biomolecules. Zink, J. I.; Dunn, B.; Valentine, J. S.; Yamanaka, S.; Akbarian, F. Mat. Sci. Eng. A, 1995, 73, 264-265.

111. Mutations Associated With Amyotrophic Lateral Sclerosis Convert Superoxide Dismutase From an Antiapoptotic Gene to a Proapoptotic Gene: Studies in Yeast and Neural Cells. Rabizadeh, S.; Gralla, E. B.; Borchelt, D. R.; Gwinn, R.; Valentine, J. S.; Sisodia, S.; Wong, P.; Lee, M.; Hahn, H.; Bredesen, D. E. Proc. Natl. Acad. Sci. USA, 1995, 3024-3028.

110. Copper-Zinc Superoxide Dismutase: Mechanistic and Biological Studies. Valentine, J. S.; Ellerby, L. M.; Graden, J. A.; Nishida, C. A.; Gralla, E. B. "Bioinorganic Chemistry", D. P. Kessissoglou, ed., Kluwer Academic Publishers, Netherlands, 1995, 77-91.

109. Measurement of Dissolved Oxygen in Water Using Glass-Encapsulated Myoglobin. Chung, K. E.; Lan, E. H.; Davidson, M. S.; Dunn, B.; Valentine, J. S.; Zink, J. I. Anal. Chem., 1995, 34, 1505-1509.

108. Modeling the Reactivity of a-Ketoglutarate-Dependent Non-Heme Iron(II)-Containing Enzymes. Ha, E. H.; Ho, R. Y. N.; Kisiel, J. F.; Valentine, J. S. Inorg. Chem., 1995, 34, 2265-2266.

107. Dioxygen Reactions. Valentine, J. S. in Bioinorganic Chemistry (textbook). Bertini, I.; Gray, H. B.; Lippard, S. J.; Valentine, J. S. University Science Books, Mill Valley, California, 1994.

106. Biomolecular Materials Based on Sol-Gel Encapsulated Proteins. Zink, J. I.; Valentine, J. S.; Dunn, B. New J. Chem., 1994, 18, 1109-1115.

105. Encapsulation and Reactivity of the Enzyme Oxalate Oxidase in a Sol-Gel Derived Glass. Yamanaka, S. A.; Nguyen, N. P.; Ellerby, L. M.; Dunn, B.; Valentine, J. S.; Zink, J. I. J. Sol-Gel Sci. and Tech., 1994, 2, 827-829.

104. Epoxidation of Olefins by Iodosylbenzene Catalyzed by Non-Porphyrin Metal Complexes. Nam, W.; Baek, S. J.; Liao, K. I.; Valentine, J. S. Bull. Korean Chem. Soc., 1994, 15, 1112-1118.

103. Biomolecular Materials Based on Sol-Gel Encapsulated Proteins. Zink, J. I.; Yamanaka, S. A.; Ellerby, L. N.; Valentine, J. S.; Nishida, F.; Dunn, B. Journal of Sol-Gel Science and Technology, 1994, 2, 791-795.

102. Raman Spectroscopy as an Indicator of Cu-S Bond Length in Type 1 and Type 2 Copper Cysteinate Proteins. Andrew, C. R.; Yeom, H.; Valentine, J. S.; Karlsson, B. G.; Bonander, N.; van Pouderoyen, G.; Canters, G. W.; Loehr, T.; Sanders-Loehr, J. J. Am. Chem. Soc., 1994, 116, 11489-11498.

101. Role of the Bridging Histidyl Imidazolate Ligand in Yeast Copper-Zinc Superoxide Dismutase. Characterization of the His63Ala Mutant. Graden, J. A.; Ellerby, L. M.; Roe, J. A.; Valentine, J. S. J. Am. Chem. Soc., 1994, 116, 9743-9744.

100. Sol-Gel Encapsulation Methods for Biosensors. Dave, B. C.; Dunn, B.; Valentine, J. S.; Zink, J. I. Anal. Chem., 1994, 66, 1120A-1127A.

99. Characterization of Three Yeast Copper-Zinc Superoxide Dismutase Mutants Analogous to Those Coded for in Familial Amyotrophic Lateral Sclerosis. Nishida, C.; Gralla, E. B.; Valentine, J. S., Proc. Natl. Acad. Sci. U.S.A., 1994, 91, 9906-9910.

98. Studies of CuZnSOD in Saccharomyces cerevisiae. Gralla, E. B.; Ellerby, L. M.; and Valentine, J. S. in "Biological Oxidants and Antioxidants", Packer, L. and Cadenas, E., eds., Hippokrates Verlag, Stuttgart, 1994, 261-266.

97. Bcl-2 Inhibition of Neural Death: Decreased Generation of Reactive Oxygen Species. Kane, D. J.; Sarafian, T. A.; Anton, R.; Hahn, H.; Gralla, E. B.; Valentine, J. S.; Ord, T.; Bredesen, D. E. Science, 1993, 262, 1274-1277.

96. Non-Porphyrin Iron Complex-Catalyzed Epoxidation of Olefins. Valentine, J.S.; Nam, W.; Ho, R.Y.N. in "The Activation of Dioxygen and Homogeneous Catalytic Oxidation," Barton, D. H. R.; Martell A. E.; and Sawyer, D., eds., Plenum Publishing Corporation, 1993, 183-198.

95. Resonance Raman Excitation Profiles Indicate Multiple Cysteine-to-Copper Charge Transfer Transitions in Type 1 Copper Proteins. Han, J.; Loehr, T. M.; Lu, Y.; Valentine, J. S.; Averill, B. A.; Sanders-Loehr, J. J. Am. Chem. Soc., 1993, 115, 4256-4263.

94. Metalloprotein Ligand Redesign: Characterization of Copper-Cysteinate Proteins Derived from Yeast Copper-Zinc Superoxide Dismutase. Lu, Y.; Gralla, E. B.; Valentine, J. S. in "Bioinorganic Chemistry of Copper", Karlin, K. D.; Tyeklár, Z., eds., Chapman & Hall, 1993, 64-77.

93. Yeast and Mammalian Metallothioneins Functionally Substitute for Yeast Cu-Zn Superoxide Dismutase. Tamai, K. T.; Gralla, E. B.; Ellerby, L. M.; Valentine, J. S.; Thiele, D. J. Proc. Natl. Acad. Sci. U.S.A., 1993, 90, 8013-8017.

92. Construction of a "Blue" Copper Site at the Native Zinc Site of Yeast Cu-Zn Superoxide Dismutase. Lu, Y.; LaCroix, L.B.; Lowery, M. D.; Solomon, E. I.; Bender, C. J.; Peisach, J.; Roe, J. A.; Gralla, E. B.; Valentine, J. S. J. Am. Chem. Soc., 1993, 115, 5907-5918.

91. Reevaluation of the Significance of ¹⁸O Incorporation in Metal Complex- Catalyzed Oxygenation Reactions Carried Out in the Presence of H₂¹⁸O. Nam, W.; Valentine, J. S. J. Am. Chem. Soc., 1993, 115, 1772-1778.

90. ENDOR and ESEEM Investigation of Ag(I)₂Cu(II)₂ Bovine Superoxide Dismutase. Gurbiel, R. J.; Peoples, R.; Doan, P. E.; Cline, J. F.; McCracken, J.; Peisach, J.; Hoffman, B. M.; Valentine, J. S. Inorg. Chem., 1993, 32, 1813-1819.

89. Bacteriorhodopsin Encapsulated in Transparent Sol-Gel Glass: A New Biomaterial. Wu, S.; Ellerby, L. M.; Cohan, J. S.; Dunn, B.; El-Sayed, M. A.; Valentine, J. S.; Zink, J. I. Chem. Mater., 1993, 5, 115-120.

88. Two-Dimensional ¹H NMR Studies of the Paramagnetic Mettalloenzyme Copper-Nickel Superoxide Dismutase. Bertini, I.; Luchinat, C.; Ming, L.-J.; Piccioli, M.; Sola M.; Valentine, J. S. Inorg. Chem., 1992, 31, 4433-4435.

87. Yeast Lacking Superoxide Dismutase: Isolation of Genetic Suppressors. Liu, X. F. ; Elashvili, I.; Gralla, E. B.; Valentine, J. S.; Lapinskas, P.; Culotta, V. C. J. Biol. Chem., 1992, 267, 18298-18302.

86. The Redesign of a Type 2 into a Type 1 Copper Protein: Construction and Characterization of Yeast Cu-Zn Superoxide Dismutase Mutants. Lu, Y.; Gralla, E. B.; Roe, J. A.; Valentine, J. S. J. Am. Chem. Soc. 1992, 114 , 3560-3562.

85. Encapsulation of Proteins in Optically Porous Silicate Glasses Prepared by the Sol-Gel Method. Ellerby, L. M.; Nishida, C. R.; Nishida, F.; Yamanaka, S. A.; Dunn, B.; Valentine, J. S.; Zink, J. I. Science, 1992, 255, 1113-1115.

84. Enzymatic Activity of Glucose Oxidase Encapsulated in Transparent Glass by the Sol-Gel Method: Immobilization of Glucose Oxidase and Peroxidase. Yamanaka, S. A.; Nishida, F.; Nishida, C.; Ellerby, L. M.; Dunn, B.; Valentine, J. S.; Zink, J. I. Chem. Mater., 1992, 4, 495-497.

83. Spectroelectrochemistry of Copper-Zinc Superoxide Dismutase. St. Clair, C. S.; Gray, H. B.; Valentine, J. S. Inorg. Chem., 1992, 31, 925-927.

82. Is Intramolecular Hydrogen-Bonding Important for Bleomycin Reactivity? A Molecular Mechanics Study. Wu, Y.; Houk, K. N.; Valentine, J. S.; Nam, W. Inorg. Chem., 1992, 31, 718-720.

81. Null Mutants of Saccharomyces cerevisiae Cu, Zn Superoxide Dismutase: Characterization and Spontaneous Mutation Rates. Gralla, E. B.; Valentine, J. S. J. Bacteriol., 1991, 173, 5918-5920.

80. ACE1, a Copper-Dependent Transcription Factor, Activates Expression of the Yeast Copper, Zinc Superoxide Dismutase Gene. Gralla, E. B.; Thiele, D. J.; Silar, P.; Valentine, J. S. Proc. Natl. Acad. Sci. U.S.A., 1991, 88, 8558-8562.

79. Lewis Acidic Catalysts for Olefin Epoxidation By Iodosylbenzene, Yang, Y.; Diederich, F.; Valentine, J. S. J. Am. Chem. Soc., 1991, 113, 7195-7205.

78. Iron-Cyclam Complexes as Catalysts for the Epoxidation of Olefins by 30% Aqueous Hydrogen Peroxide in Acetonitrile and Methanol. Nam, W.; Ho, R.; Valentine, J. S. J. Am. Chem. Soc., 1991, 113, 7052-7054.

77. ³⁵Cl and ¹H NMR Study of Anion Binding to Reduced Bovine Copper-Zinc Superoxide Dismutase. Mota de Freitas, D.; Ming, L.-J.; Ramasamy, R.; Valentine, J. S. Inorg. Chem., 1990, 29 3512-3518.

76. Reaction of Cyclohexene with Iodosylbenzene Catalyzed by Non-Porphyrin Complexes of Iron(III) and Aluminium(III). Newly Discovered Products and New Mechanistic Proposal. Yang. Y.; Diederich, F.; Valentine, J. S. J. Am. Chem. Soc., 1990, 112, 7826-7828.

75. Zinc(II) Complexes and Aluminum(III) Porphyrin Complexes Catalyze the Epoxidation of Olefins by Iodosylbenzene. Nam, W.; Valentine, J. S. J. Am. Chem. Soc., 1990, 112, 4977-4979.

74. Complexometric Titrations of Protein-Bound Metal Ions: A Method for Determining Binding Constants. Roe, J. A.; Valentine, J. S. Anal. Biochem., 1990, 186, 31-40.

73. NMR Studies of Nickel(II)-Substituted Derivatives of Bovine Copper-Zinc Superoxide Dismutase with Nickel(II) Bound in the Copper Site. Ming, L.-J.; Valentine, J. S. J. Am. Chem. Soc., 1990, 112, 6374-6383.

72. NMR Studies of Cobalt(II)-Substituted Derivatives of Bovine Copper-Zinc Superoxide Dismutase. Effects of pH, Phosphate, and Metal Migration. Ming, L.-J.; Valentine, J. S. J. Am. Chem. Soc., 1990, 112, 4256-4264.

71. Silver Binding Properties of Bovine Cuprozinc Superoxide Dismutase and the Overall Stability of Selected Metal-Ion Derivatives. Roe, J. A.; Peoples, R.; Scholler, D. M.; Valentine, J. S. J. Am. Chem. Soc., 1990, 112, 1538-1545.

70. Hydroxylation of Alkanes by Hydrogen Peroxide Catalyzed by Iron Complexes in the Presence of Pyridine or 2,2'-Bipyridine. Nam, W.; Valentine, J. S. New J. Chem., 1989, 13, 677-682.

69. Oxygen Atom Transfer Reactions at Binuclear Copper Sites. Margerum, L.D.; Liao, K.I.; Valentine, J. S. "Oxygen Atom Transfer Reactions at Binuclear Copper Sites. ACS Symposium, Metal Clusters in Proteins, L. Que, Ed., 1988, pp. 105-115.

68. Characterization of Copper-Nickel and Silver-Nickel Bovine Superoxide Dismutase by H NMR Spectroscopy. Ming, L.-J.; Banci, L.; Luchinat, C.; Bertini, I.; Valentine, J.S. Inorg. Chem., 1988, 27, 4458-4463.

67. Cloning and Biological Activity of The CuZnSOD Gene of S. Cerevisiae. Gralla, E. B.; Bermingham-McDonogh, O.; Valentine, J. S.; Chang, E.; Kreuger, T.; Kosman, D. "Oxy-Radicals in Molecular Biology and Pathology", UCLA Symposia on Molecular and Cellular Biology, New Series, Vol. 82, P. Cerutti, I. Fridovich, and J. McCord, Eds., 1988, pp. 173-182.

66. NMR Study of Cobalt(II)-Substituted Yeast and Human Copper-Zinc Superoxide Dismutase. Ming, L.-J.; Banci, L.; Luchinat, C.; Bertini, I.; Valentine, J. S. Inorg. Chem., 1988, 27, 723-733.

65. The Cu,Zn-Superoxide Dismutase Gene of S. Cervisiae - Cloning, Sequencing, and Biological Activity. Bermingham-McDonogh, O.; Gralla, E. B.; Valentine, J. S. Proc. Natl. Acad. Sci. U.S.A., 1988, 85, 4789-4793.

64. Epoxidation of Olefins by Iodosylbenzene Catalyzed by Metal Ions and Metal Complexes. Valentine, J. S.; VanAtta, R. B.; Margerum L. D.; Yang, Y. in "Activation of Dioxygen and Homogeneous Catalytic Oxidations", W. Ando, Ed., Elsevier, New York, 1988, pp. 175-184.

63. Mechanisms of Dioxygen Activation in Metal-Containing Monooxygenases: Enzymes and Model Systems. Valentine, J. S.; Burstyn, J. N.; Margerum, L. D. in "Oxygen Complexes and Oxygen Activation by Metal Complexes", A. Martell, Ed., Plenum Publishing Corp., New York, 1988, pp. 175-187.

62. Magnetic and Spectroscopic Characterization of an Iron Porphyrin Peroxide Complex. Peroxoferrioctaethylporphyrin(1-). Burstyn, J. N.; Roe, J. A.; Miksztal, A. R.; Shaevitz, B. A.; Lang, G.; Valentine, J. S. J. Am. Chem. Soc., 1988, 110, 1382-1388.

61. Differential Scanning Calorimetry of Cu,Zn Superoxide Dismutase, the Apoprotein, and Its Zinc-Substituted Derivatives. Roe, J. A.; Butler, A.; Scholler, D. M.; Valentine, J. S.; Marky, L.; Breslauer, K. Biochemistry., 1988, 27, 950-958.

60. Preparation and Spectroscopic Characterization of Cu₂Ni₂ and Ag₂Ni₂ Superoxide Dismutase, Two New Metal-Substituted Derivatives. Ming, L.-J.; Valentine, J. S. J. Am. Chem. Soc., 1987, 109, 4426-4428.

59. 31P NMR Study of the Interaction of Inorganic Phosphate with Bovine Copper-Zinc Superoxide Dismutase. Mota de Freitas, D.M.; Luchinat, C.; Banci, L.; Bertini, I.; Valentine, J.S. Inorg. Chem., 1987, 26, 2788-2791.

58. Electronic Structure of Low-Spin Ferric Porphyrins: A Single-Crystal EPR and Structural Investigation of the Influence of Axial Ligand Orientation and the Effects of Pseudo-Jahn-Teller Distortion. Quinn, R.; Valentine, J. S.; Byrn, M. P.; Strouse, C. E. J. Am. Chem. Soc., 1987, 109, 3301-3308.

57. [Peroxotetraphenylporphinato] manganese(III) and [Chlorotetraphenylporphinato] manganese(II) Anions. Syntheses, Crystal Structures, and Electronic Structures. VanAtta, R. B.; Strouse, C. E.; Hanson, L. K.; Valentine, J. S. J. Am. Chem. Soc., 1987, 109, 1425-1434.

56. Epoxidation of Olefins by Iodosylbenzene Catalyzed by Binuclear Copper(II) Complexes. Tai, A. F.; Margerum, L. D.; Valentine, J. S. J. Am. Chem. Soc., 1986, 108, 5006-5008.

55. NMR Studies of the Anion Binding Sites of Oxidized and Reduced Bovine Copper-Zinc Superoxide Dismutase. Valentine, J. S.; Mota de Freitas, D. in "Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine"; Rotilio, G., Ed.; Elsevier Science Publishers: Amsterdam, 1986, pp. 149-154.

54. Direct Formation of Complexes Between Cytochrome P-450 and Nitrosoarenes. Fukoto, J. M.; Brady, J. F.; Burstyn, J. N.; VanAtta, R. B.; Valentine, J. S.; Cho, A. K. Biochemistry., 1986, 25, 2714-2719.

53. Studies of Copper-Zinc Superoxide Dismutase: The Role of Zinc and of the Essential Arginine Residue. Valentine, J. S.; Roe, J. A.; Butler, A.; Mota de Freitas, D. In "Biological & Inorganic Copper Chemistry", Vol. I; Karlin, K. D.; Zubieta, J., Eds.; Adenine Press: Guilderland, N.Y., 1986, pp. 53-60.

52. Copper-Zinc Superoxide Dismutase. A Unique Biological "Ligand" for Bioinorganic Studies. Valentine, J. S.; Mota de Freitas, D. J. Chem. Educ., 1985, 62, 990-997.

51. The Mechanism of Oxidation of N-Hydroxyphentermine by Superoxide. Fukuto, J. M.; Di Stephano, E. W.; Burstyn, J. N.; Valentine, J. S.; Cho, A. Biochemistry, 1985, 24, 4161-4167.

50. Oxygenation of Organic Substrates by Iodosylbenzene Catalyzed by Soluble Manganese, Iron, Cobalt or Copper Salts in Acetonitrile. VanAtta, R. B.; Franklin, C. C.; Valentine, J. S. Inorg. Chem., 1984, 23, 4121-4123.

49. Reactivity of the Peroxo Ligand in Metalloporphyrin Complexes. Reaction of Sulfur Dioxide with Iron and Titanium Porphyrin Peroxo Complexes to Give Sulfato Complexes or Sulfate. Miksztal, A. R.; Valentine, J. S. Inorg. Chem., 1984, 23, 3548-3552.

48. The Influence of Hydrogen Bonding on the Properties of Iron Porphyrin Complexes. An Internally Hydrogen Bonded Imidazole Ligand. Quinn, R.; Mercer-Smith, J.; Burstyn, J. N.; Valentine, J. S. J. Am. Chem. Soc., 1984, 106, 4136-4144.

47. Copper Ion-Mediated Epoxidation of Olefins by Iodosylbenzene. Franklin, C. C.; VanAtta, R. B.; Tai, A. F.; Valentine, J. S. J. Am. Chem. Soc., 1984, 106, 814-816.

46. Phosphate is an Inhibitor of Copper-Zinc Superoxide Dismutase. Mota de Freitas, D.; Valentine, J. S. Biochemistry, 1984, 23, 2079-2082.

45. Influence of Adrenalectomy and Dexamethasone on Rat Liver Metallotheionein and Superoxide Dismutase Activity. Hutchings, L. L.; Scholler, D. M.; Valentine, J. S.; Swerdel, M. R.; Etzel, K. R.; Cousins, R. J. Inorg. Chim. Acta, 1984, 91, L21-L22.

44. Methods for the Study of Superoxide Chemistry in Nonaqueous Solutions. Valentine, J. S.; Miksztal, A. R.; Sawyer, D. T. Methods Enzymol., 1984, 105, 71-81.

43. Concerning the Radical Character of Superoxide. The H-O Bond Energy of HO₂. Liebman, J. F.; Valentine, J. S. Israel J. Chem., 1983, 23, 439-441.

42. Crystal Structure and Properties of a Potassium Cryptate Salt of Bis(4-methylimidazolato) (tetraphenylporphinato)iron(III). Quinn, R.; Strouse, C. E.; Valentine, J. S. Inorg. Chem., 1983, 22, 3932-3940.

41. Reduced Anion-Binding Affinity of Cu, Zn Superoxide Dismutases Chemically Modified at Arginine. Bermingham-McDonogh, O.; Mota de Freitas, D.; Kumamoto, A.; Saunder, J. E; Blech, D. M.; Borders, C. L., Jr.; Valentine, J. S. Biochem. Biophys. Res. Commun., 1982, 108, 1376-1382.

40. A pH-Dependent Superoxide Dismutase Activity for Zinc-Free Bovine Erythrocuprein. Reexamination of the Role of Zinc in the Holoprotein. Pantoliano, M. W.; Valentine, J. S.; Burger, A. R.; Lippard, S. J. J. Inorg. Biochemistry, 1982, 17, 325-341.

39. Spectroscopic Studies of Copper(II) Bound at the Native Site or Substituted at the Native Zinc Binding Site of Bovine Erythrocuprein (Superoxide Dismutase). Pantoliano, M. W.; Nafie, L. A.; Valentine, J. S. J. Am. Chem. Soc., 1982, 104, 6310-6317.

38. New Five- and Six-Coordinate Imidazole and Imidazolate Complexes of Ferric Tetraphenylporphyrin. Quinn, R.; Nappa, M.; Valentine, J. S. J. Am. Chem. Soc., 1982, 104, 2588-2595.

37. pH Dependence of Metal Ion Binding to the Native Zinc Site of Bovine Erythrocuprein (Superoxide Dismutase). Pantoliano, M. W.; Valentine, J. S.; Mammone, R. J.; Scholler, D. M. J. Am. Chem. Soc., 1982, 104, 1717-1723.

36. Modes of Bonding of Dioxygen, Oxide, and Hydroxide to Iron Porphryins and Copper. Conceivable Structures for the Oxygenated Intermediates of Cytochrome c Oxidase. Valentine, J. S.; McCandlish, E. In "Electron Transport and Oxygen Utilization"; Ho, C. Ed.; Elsevier North Holland: New York, 1982, pp. 229-235.

35. How Super is Superoxide? Sawyer, D. T.; Valentine, J. S. Acc. Chem. Res., 1981, 14, 393-400.

34. Protein-Metal Ion Interactions in Cuprozinc Protein (Superoxide Dismutase), a Major Intracellular Repository for Copper and Zinc in the Eukaryotic Cell. Valentine, J. S.; Pantoliano, M. W. In "Copper Proteins"; Spiro, T. G.; Ed., "Metals in Biology Series", Vol. 3; Wiley: New York, 1981, pp. 292-358.

33. Nuclear Magnetic Resonance Study of the Exchangeable Histidine Protons in Bovine and Wheat Germ Superoxide Dismutases. Burger, A. R.; Lippard, S. J.; Pantoliano, M. W.; Valentine, J. S. Biochemistry, 1980, 19, 4139-4143.

32. Reactions of Superoxide with Iron Porphyrins in Aprotic Solvents. A High Spin Ferric Porphyrin Peroxo Complex. McCandlish, E.; Miksztal, A. R.; Nappa, M.; Sprenger, A. Q.; Valentine, J. S; Stong, J. D.; Spiro, T. G. J. Am. Chem. Soc., 1980, 102, 4268-4271.

31. Metal Binding Properties of Copper-Zinc Superoxide Dismutase. Valentine, J. S.; Pantoliano, M. W. In "Chemical and Biochemical Aspects of Superoxide and Superoxide Dismutase"; Bannister, J. V.; Hill, H. A. O., Eds.; Elsevier/North Holland: New York, 1980, pp. 254-264.

30. Reactions of Superoxide in Aprotic Solvents. A Superoxo Complex of Copper(II) rac-5,7,7,12,14,14-Hexamethy1-1,4,8,11-tetraazacyclotetradecan. Nappa, M.; Valentine, J. S.; Miksztal, A. R.; Schugar, H. J.; Isied, S. S. J. Am. Chem. Soc., 1979, 101, 7744-7746.

29. Reversible Loss of Metal Ions from the Zinc Bonding Site of Copper-Zinc Superoxide Dismutase. The Low pH Transition. Pantoliano, M. W.; McDonnell, P. J.; Valentine, J. S. J. Am. Chem. Soc., 1979, 101, 6454-6456.

28. Kinetics of CO Binding to Fe(TPP)(Im) and Fe(TPP)(Im^-): Evidence Regarding Protein Control of Heme Reactivity. Swartz, J. C.; Stanford, M. A.; Moy, J. N.; Hoffman, B. M.; Valentine, J. S. J. Am. Chem. Soc., 1979, 101, 3396-3398.

27. Infrared Frequency Lowering of the C-O Stretching Mode of Carbon Monoxyhemoglobin Kansas Associated with the R T Switch. Kincaid, J. R.; Spiro, T. G.; Valentine, J. S.; Saperstein, D. D.; Rein, A. J. Inorg. Chim. Acta, 1979, 33, L181-L182.

26. pH Dependent Migration of Copper(II) to the Vacant Zinc Binding Site of Zinc-Free Bovine Erythrocyte Superoxide Dismutase. Valentine, J. S.; Pantoliano, M. W.; McDonnell, P. J.; Burger, A. R.; Lippard, S. J. Proc. Natl. Acad. Sci. U.S.A., 1979, 76, 4245-4249.

25. Coupling Between Oxidation State and Hydrogen Bond Conformation in Heme Proteins. Valentine, J. S.; Sheridan, R. P.; Allen, L. C.; Kahn, P. C. Proc. Natl. Acad. Sci. U.S.A., 1979, 76, 1009-1013.

24. The Chemical Reactivity of Superoxide Anion in Aprotic Versus Protic Media: A Review. Valentine, J. S. In "Biochemical and Clinical Aspects of Oxygen"; Caughey, W. S., Ed.; Academic Press: New York, 1979, pp. 659-677.

23. Reactions of Superoxide with Metalloporphyrins. Valentine, J. S.; McCandlish, E. In "Frontiers of Biological Energetics", Vol. II; Dutton, P. L.; Leigh, J. S.; Scarpa, A., Eds.; Academic Press: New York, 1978, pp. 933-940.

22. The Influence of Axial Ligands on Metalloporphyrin Visible Absorption Spectra. Complexes of Tetraphenylporphinatozinc. Nappa, M.; Valentine, J. S. J. Am. Chem. Soc., 1978, 100, 5075-5080.

21. Imidazolate Complexes of Ferric Porphyrins. Nappa, M.; Valentine, J. S.; Snyder, P. A. J. Am. Chem. Soc., 1977, 99, 5799-5800.

20. Superoxotetraphenylporphinatozinc(1-). Valentine, J. S.; Tatsuno, Y.; Nappa, M. J. Am. Chem. Soc., 1977, 99, 3522-3523.

19. Chemical and Physical Properties of Superoxide. Fee, J. A.; Valentine, J. S. In "Superoxide and Superoxide Dismutases"; Michelson, A. M.; McCord, J. M.; Fridovich, I., Eds.; Academic Press: London, 1977, pp.19-60.

18. Nuclear Magnetic Resonance and Chemical Modification Studies of Bovine Erythrocyte Superoxide Dismutase: Evidence for Zinc-Promoted Organization of the Active Site Structure. Lippard, S. J.; Burger, A. R.; Ugurbil, K.; Pantoliano, M. W.; Valentine, J. S. Biochemistry, 1977, 16, 1136-1141.

17. Physical and Chemical Studies of Bovine Erythrocyte Superoxide Dismutase. Lippard, S. J.; Burger, A. R.; Ugurbil, K.; Valentine, J. S.; Pantoliano, M. W. Adv. Chem. Ser., 1977, 162, 251-262.

16. Reaction of Superoxide with the Manganese(III) Tetraphenylporphine Cation. Valentine, J. S.; Quinn, A. E. Inorg. Chem., 1976, 15, 1997-1999.

15. Oxidative Cleavage of a-Keto, a-Hydroxy, and a-Halo Ketones, Esters, and Carboxylic Acids by Superoxide. San Filippo, J., Jr.; Chern, C.-I.; Valentine, J. S. J. Org. Chem., 1976, 41, 1077-1078.

14. Cleavage of Esters by Superoxide. San Filippo, J., Jr.; Romano, L. J.; Chern, C.-I.; Valentine, J. S. J. Org. Chem., 1976, 41, 586-588.

13. Structures of Becton's [Pt (NH₃)₄CuCl₄] and Millon's [Cu(NH₃)₄PtCl₄] Salts. Morosin, B.; Fallon, P.; Valentine, J. S. Acta Crystallogr., 1975, B31, 2220-2223.

12. The Reaction of Superoxide with Alkyl Halides and Tosylates. San Filippo, J., Jr.; Chern, C. I.; Valentine, J. S. J. Org. Chem., 1975, 40, 1678-1680.

11. A Convenient Preparation of Solutions of Superoxide Anion and the Reaction of Superoxide Anion with a Copper(II) Complex. Valentine, J. S.; Curtis, A. B. J. Am. Chem. Soc., 1975, 97, 224-226.

10. Interdimer Exchange in Linear Chain Copper Acetate-Pyrazine. Valentine, J. S.; Silverstein, A. J.; Soos, Z. G. J. Am. Chem. Soc., 1974, 96, 97-103.

9. The Dioxygen Ligand in Mononuclear Group VIII Transition Metal Complexes. Valentine, J. S. Chem. Rev., 1973, 73, 235-245.

8. A New Hydrido-iridium(III) Isomer of Ir(PPh₃)₂(CO)Cl. Valentine, J. S. J. Chem. Soc., Chem. Commun.,1973, 857-858.

7. Spin Correlation Functions in Cu(NH₃)₄PtCl₄. Soos, Z.G.; Huang, T.Z.; Valentine, J. S.; Hughes, R. C. Phys. Rev. B, 1973, 8, 993-1002.

6. Preparation and Photochemical Decompositions of Acido-Substituted µ-Superoxo-dicobalt-Ammine Derivatives. Valentine, J. S.; Valentine, D., Jr. Inorg. Chem., 1973, 12, 1686-1699.

5. Photochemical Decomposition of two µ-Superoxo-dicobalt Ammines in Acidic Aqueous Solutions. Valentine, J. S.; Valentine D., Jr. J. Am. Chem. Soc., 1971, 93, 1111-1117.

4. The Photochemistry of (en)₂Co(NH₂)(O₂)Co(en)2⁴⁺. Valentine, J. S.; Valentine D., Jr. Inorg. Chem., 1971, 10, 393-395.

3. The Formation of Chelated Sulfate by Reactions between Sulfur Dioxide and Oxygen in the Coordination Sphere of Iridium and Ruthenium Complexes. Valentine, J. S.; Valentine, D., Jr.; Collman, J. P. Inorg. Chem., 1971, 10, 219-225.

2. Photoinduced Oxidative Addition of 9,10-Phenanthrenequinone to Ir(PPh₃)₂(CO) (Cl). Valentine, J. S.; Valentine, D. Jr. J. Am. Chem. Soc., 1970, 92, 5795-5797.

1. Excited States of Transition Metal Complexes in Solution. Valentine, D., Jr.; Valentine, J. S.; Sarver, B. in "Proceedings of a Symposium on Electronically Excited States", Gordon Beach, Inc., 1970, 151-156.

NON PEER-REVIEWED ARTICLES

3. Bio-Inorganic Chemistry: What Is It, and What’s So Exciting? Valentine, J. S.; O’Halloran, T. V., Curr. Opin. Chem. Biol., 1999, 3, 129-130.

2. Previous Sol-Gel Enzymes. Dunn, B.; Valentine, J. S.; Zink, J. I., Science, 1992, 257, 147-147.

1. Women in Science - Response. Valentine, J. S., Science, 1992, 256, 1615-1615.

BOOKS

Biological Inorganic Chemistry: Structure and Reactivity, Bertini, I., Gray, H.B., Stiefel, E.I. and Valentine, J.S., eds., University Science Books, Sausalito, CA 2006

Active Oxygen in Biochemistry. Valentine, J. S.; Foote, C. S.; Greenberg, A.; Liebman, J. F., eds., Blackie Academic & Professional, Chapman & Hall, Glasgow, 1995.

Active Oxygen in Chemistry. Foote, C. S.; Valentine, J. S.; Greenberg, A.; Liebman, J. F., eds., Blackie Academic & Professional, Chapman & Hall, Glasgow, 1995.

Bioinorganic Chemistry (textbook). Bertini, I.; Gray, H. B.; Lippard, S. J.; Valentine, J. S. University Science Books, Mill Valley, California, 1994.

PATENT

Sol-Gel Encapsulated Enzyme. Zink, J. I.; Dunn, B.; Valentine, J. S.; Ellerby, L. M.; Nishida, F.; Nishida, C.;Yamanaka, S. A., Serial No. 07/744,524, U.S. Letters Patent No. 5,200,334.

Method of Modulating Radical Formation By Mutant Cuznsod Enzymes. Bredesen, D. E.; Valentine, J. S.; Gralla, E.; Goto, J. J.; Wiedau-Pazos, M., U.S. Patent No. 5,834,457.