Illustrated Glossary of Organic Chemistry

Toluenesulfonic acid (p-toluenesulfonic acid; TsOH; p-TsOH): An aromatic sulfonic acid, often used as a strong acid catalyst. Most commonly refers to para-methylbenzenesulfonic acid monohydrate (CH3C6H4SO3H.H2O; pKa -2), but the anhydrous form may also be used.


Molecular structure of toluenesulfonic acid.


cat. TsOH

CH3OH

TsOH catalysis in the Fischer esterification reaction.