Functional Group Preparations

Nitro 

Aryl nitro compounds are prepared by electrophilic aromatic substitution of an aryl hydrogen atoms using a mixture of nitric and sulfuric acids.  The electrophile is the nitronium ion (NO2+).  The substituents on the ring determine the position of the new nitro group.  Multiple nitration is usually not a problem.  Because the nitro group is deactivating, addition of subsequent nitro groups is much more difficult (Section 9.7B).


Link to: