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Publications




2000-2004

  1. Lin Li, Ranny Mathew Thomas, Hidetaka Suzuki, Jef K. De Brabander, Xiaodong Wang and Patrick G. Harran (2004) A Small Molecule Smac Mimic Potentiates TRAIL and TNFα-Mediated Cell Death Science, 305, 1471-1474.


    Commentary:
    1) Medicine: Targeting Apoptotic Pathways in Cancer Cells (2004) Science 305, 1411-1413.
    2) Activate Apoptosis; Kill a Tumor (2004)The Lancet Oncology 5 (10), 583.
    3) New Apoptosis Drug Faces Critical Test (2005) Nature Biotechnology 23, 409-411.

  2. Anthony Burgett, Qingyi Li, Qi Wei, and Patrick G. Harran (2003) A Concise and Flexible Total Synthesis of (–)-Diazonamide A Angew. Chem Intl. Ed. Engl., 42, 4961-4966.

  3. Qi Wei, Susan Harran, and Patrick G. Harran (2003) Methods to Initiate Synthetic Re-Structuring of Peptides Tetrahedron (symposium-in-print) 59, 8947-8954.

  4. Zobeida Cruz-Monserrate, Jeffrey T. Mullaney, Patrick G. Harran, George R. Pettit and Ernest Hamel (2003) Dolastatin 15 Binds in the Vinca Domain of Tubulin as Demonstrated by Hummel-Dreyer Chromatography Eur. J. Biochem., 3822-3828.

  5. Jing Li, Susan Jeong, Lothar Esser, and Patrick G. Harran (2001) Total Synthesis of Nominal Diazonamides: Part 1. Convergent Preparation of the Structure Proposed for (–)-Diazonamide A. Angew. Chem Intl. Ed. Engl., 40, 4765-4770.

  6. Jing Li, Anthony Burgett, Lothar Esser, Carlos Amezcua, and Patrick G. Harran (2001) Total Synthesis of Nominal Diazonamides: Part 2. On the True Structure and Origin of Natural Isolates. A.Angew. Chem Intl. Ed. Engl., 40, 4770-4773.


    Commentary:
    1) Total Synthesis Surprise. (December 2001) Chemical and Engineering News. 79(51).
    2) The Diazonamides: The Plot Thickens. (2002) Angew. Chem. Intl. Ed. Engl. 41(14), 2489-2495.
    3) Chemtracts: Org. Chem., 15, 481-486 (2002).
    4) Classics in Total Synthesis II, Wiley-VCH (2003) Chapter 20.

  7. Jing Li, Xin Chen, Anthony Burgett, and Patrick G. Harran (2001) Synthetic seco Forms of (–)- Diazonamide A. Angew. Chem Intl. Ed. Engl., 40, 2682-2685.

  8. Xin Chen, Lothar Esser, and Patrick G. Harran (2000) Stereocontrol in Pinacol Ring-Contraction of Cyclopeptidyl Glycols: The Diazonamide C10 Problem. A.Angew. Chem Intl. Ed. Engl., 39, 937-940.

  9. Troy D. Ryba and Patrick G. Harran (2000) Two Useful Photolabile Surfaces for Solid Phase Synthesis. Organic Letters, 2, 851-853.