Curriculum Vitae

Adam Z. Stieg @ the CNSI - UCLA

| home | back to About |

Current research involves the design, fabrication and application of scanning probe microscopic techniques toward high-speed, high-resolution analyses of naoscale systems.

1995 - Graduated with highest honors. Harry D. Jacobs High School, Algonquin, IL. GPA 3.98

1999 - Graduated Magna Cum Laude with honors. Drew University, Madison NJ. Chemistry Major, Biology minor GPA 3.7

2004 - Recieved Master of Science in Chemistry from University of California, Los Angeles.

2007 - Received Doctor of Philosophy in Inorganic/Physical Chemistry at the University of California, Los Angeles.

Related Skills and Experience:

Experience includes the design and application of physical methods toward characterization of nanoscale systems, ranging from physical to biological, with a demonstrated proficiency in the experimental design and execution. Expertise encompasses the development of scanning probe microscopes (SPM) including atomic force microscopy (AFM) and scanning tunneling microscopy (STM) in ambient, in-situ, electrochemical and ultra-high vacuum environments. A working knowledge of practical aspects involved in the installation, setup, repair and maintenance of both commercial and home-built instrumentation has been demonstrated. Experience with commercial instrumentation includes Veeco, Nanonis, Nanosurf, and Createc SPM systems.

Extensive involvement in a variety of cross-disciplinary, collaborative ventures has provided insight into the potential advantages, pitfalls and requirements for success.

Additional synthetic and analytical techniques include: Electrochemical methods, Optical interferometry; Electron Microscopy; Energy Dispersive X-Ray Analysis (EDAX); Plasma Enhanced Chemical Vapor Deposition (PE-CVD); Nuclear magnetic resonance, atomic absorption, X-Ray fluorescence, mass (SELDI, MALDI, ESI) spectroscopy; Infrared, ATR, Raman and Resonance Raman, Fluorescence, and UV/Visible spectroscopy; gas, high performance, and liquid column chromatography; polyacrylamide, and 2D gel electrophoresis; Southern and Western blot analysis; and cell culturing techniques.

Recent Activities:

2008 ICYS-MANA Young Researcher in the CNSI Satellite Research Center for Materials NanoArchitectonics (MANA) in the National Institute of Materials Science (NIMS), Tsukuba, Japan.

2008 Scientific Director of the Sci | Art Summer Insitute at the University of California - Los Angeles, a two-week immersive course for high-school students with a focus on exposure to nanoscience research and its interface with art, society, and culture.

2008 Member of design team for 'Blue Morph', an interactive Art|Sci collaboration at the Fringe Gallery, Los Angeles.

2006 Research fellowship at Kumamoto University, Japan, investigating controlled assembly of organic molecules at the solid-liquid interface by electrochemical scanning tunneling microscopy. Advisor: Dr. Masashi Kunitake.

2005 Research internship at IBM Almaden Research Center investigating magnetic resonance force microscopy (MRFM) and its application in the detection of single nuclear spins. Advisor: Dr. Dan Rugar

2004 Member of California Nanosystems Institute Outreach Program

2003 Member of design team for Nano, a collaborative art-science exhibition at the Los Angeles County Museum of Art

Employment Experience:

Scientific Director

Current work involves the ongoing oversight of the open-access user facility in addition to providing consultation services for prospective users in order to maximize the quality and efficiency of experimental analyses. Ongoing research activites continue to include development and application of instrumentation toward understanding the fundamental properties of matter at the nanoscale.

Technical Director

Oversaw the setup and operations of an 1800 sq.ft open-access, multi-user facility focused on materials characterization through Scanning Probe Microscopy. Responsibilities included the acquisition and installation of instrumentation, user training, and preparation of associated materials including experimental protocols and technical documentation.

University of California - Los Angeles 2001-2007

Graduate Researcher

"From the Bottom Up: Instrument Design and Nanoscale Studies with Electrochemical Scanning Probe Microscopy". Doctoral thesis research involved instrumentation development, specifically the application of a home-built electrochemical SPM toward the investigation of redox active molecular and biological systems at the solid-liquid interface. STM and non-contact AFM analysis enabled quantitative measurements of structural, electronic, and mechanical properties on a wide range of surfaces and adsorbates. Advisor: James K. Gimzewski

Matritech Inc., Newton, MA 2000-2001

Research Associate II

Carried out proteomic investigations of isolated blood serum proteins as possible screening and diagnostic tools for the early detection of cancer by mass spectrometry. Isolated and characterized protein markers for both cancer of the prostate and bladder.

Nelson's Ltd. Wimbledon, UK 1999

Regulatory Affairs Officer

Generated a searchable database of reference literature on pharmaceutical products for regulatory affairs operations in the European Union.

Drew University, Madison, NJ 1997-1999

Research Assistant

“Synthesis and Characterization of Tin (IV) Complexes as Possible anti-Tumor Agents”. Addressed the application of transition metal complexes as DNA chelation agents as alternatives to cis-platin, a cancer inhibiting compound used in drug combination therapy. Honors Thesis Research. Advisor: Dr. Baldwin King

Achievements and honors:

1995 National Merit Scholar

1995 USAF student/athlete of the year

2001 UCLA President's Fellowship

2002 UCLA Department of Chemistry Excellence in Teaching Award

2003 NSF-IGERT Fellowship Award

2006 NSF/JSPS - EAPSI Fellowship Award

2008 Elected member of Executive Committee at the Calfornia NanoSytems Institute - UCLA

10. A.Z. Stieg, C. Skibo, R. Schlittler, V. Langlais, C. Joachim and J.K. Gimzewski. “Direct observation of a single molecular eight-state conformational switch” In Preparation (2008)

9. "Conformation dependent molecular pinning through rotation of a single bond" A.Z. Stieg, C. Skibo, R. Schlittler, C. Joachim and J.K. Gimzewski. In Preparation (2008)

8. "A flexible, new electrochemical scanning tunneling microscope for nanoscale studies at the solid-liquid interface" A.Z. Stieg and J.K. Gimzewski. Review of Scientific Instruments 79 (2008).

7. "Folding a polyrotaxane using secondary supramolecular interactions" W. Zhang, W. R. Dichtel, A.Z. Stieg, D. Benitez, J.K. Gimzewski, J.R. Heath, and J.F. Stoddart. Proceedings of the National Acedemy of Sciences 105, 6514-9 (2008).

6. "Observations of Image Contrast and Dimerization of Decacyclene by Low Temperature Scanning Tunneling Microscopy" Lisa Wesoloski, Adam Stieg, Masashi Kunitake, Shane Dultz, James K. Gimzewski. The Journal of Chemical Physics 127, 174703 (2007).

5. "A vertical inertial sliding drive for coarse motion and fine approach in scanning probe microscopy" A. Z. Stieg, P.Wilkinson, and J.K.Gimzewski. Review of Scientific Instruments 78, 036110 (2007).

4. “Identification and preliminary clinical evaluation of a 50.8-kDa serum marker for prostate cancer” Hlavaty John J; Partin Alan W; Shue Matthew J; Mangold LeslieA; Derby Jennifer; Javier Teofilo; Kelley Shane; Stieg Adam; Briggman Joseph V;Hass G Michael; Wu Ying-Jye. Urology 61(6), 1261-5 (2003).

3. “Mass Spectroscopy as a Discovery Tool for Identifying Serum Markers for Prostate Cancer” John J. Hlavaty, Alan W. Partin, Felicity Kusinitz, Matthew J.Shue, Adam Z. Stieg, Kate Bennett and Joseph V. Briggman. Clinical Chemistry 47: 1924-1926, (2001).

2. “Detection of Early Stage Cancer by Serum Protein Analysis” J. Briggman, B.Watkins, J. Hlavaty, A. Stieg, S. Ball. American Laboratory, 33, 32-36 (2001).

1. “Synthesis and Characterization of Tin (IV) Complexes as Possible anti-Tumor Agents” A. Stieg. Honors Thesis, Drew University Library (1999).

Selected Posters and Talks

11. “Nanomechanics in Medicine: AFM-based analysis of cancer & green tea extract (GTE)-induced anticancer properties” Keynote Lecture: CNSI-CNBI Symposium on NanoBioTechnology, Tokyo University, Japan (2008)

10. “Toward imaging molecular motion and interaction by scanning probe microscopy” Invited Talk: CNSI/G-COE Symposium, Kyushu University, Japan (2008)

9. "Integrated Nanoscale Science: Synergistic Approaches to Interfaces" Invited Talk Global Challenges - How can Nanotechnology Help? Venice, Italy (2008).

8. "Nanoscale Science and the Interface with Nature" Invited Talk NSF-MEXT US-Japan Exchange Symposium, Los Angeles, CA (2008).

7. "High Performance Imaging and Spectroscopy on Living Systems" CNSI-CNBI Symposium, Los Angeles, CA (2008).

6. "Convergent Synthesis of Mechanically Interlocked Compounds using Click Chemistry" Frontiers of Nanoscience, Snowbird, UT (2007).

5. "Dimerization of Decacylene on Copper Surfaces" ACS Spring National Meeting & Exposition, Chicago, IL (2007).

4. "From the Bottom Up: Instrument Design and Nanoscale Studies with Electrochemical Scanning Probe Microscopy" Invited Talk - Applied Chemistry, Kumamoto University, Japan (2006).

3. "Nanoscale Studies of Molecular Machines by Electrochemical Scanning Tunneling Microscopy" NSF-JSPS EAPSI Symposium, Tokyo, Japan (2006).

2. "Emerging Microscopic Techniques: Probing Matter at the Nanoscale and Beyond" NSF-IGERT Materials Creation Training Program Symposium, Los Angeles, CA (2005).

1. "Templated Electrochemical Nanopatterning: Influence of Deposition Parameters on Morphology and Future Investigations by in-situ STM" 206th meeting of the Electrochemical Society, Honolulu,HI (2004).


	Adam Z. Stieg @ the CNSI - UCLA \| home \| back to About \| Education \| Curriculum Vitae \| Publications, Posters & Talks \| Awards and Achievements Research: Current research involves the design, fabrication and application of scanning probe microscopic techniques toward high-speed, high-resolution analyses of naoscale systems. Education: 1995 - Graduated with highest honors. Harry D. Jacobs High School, Algonquin, IL. GPA 3.98 1999 - Graduated Magna Cum Laude with honors. Drew University, Madison NJ. Chemistry Major, Biology minor GPA 3.7 2004 - Recieved Master of Science in Chemistry from University of California, Los Angeles. 2007 - Received Doctor of Philosophy in Inorganic/Physical Chemistry at the University of California, Los Angeles. Related Skills and Experience: Experience includes the design and application of physical methods toward characterization of nanoscale systems, ranging from physical to biological, with a demonstrated proficiency in the experimental design and execution. Expertise encompasses the development of scanning probe microscopes (SPM) including atomic force microscopy (AFM) and scanning tunneling microscopy (STM) in ambient, in-situ, electrochemical and ultra-high vacuum environments. A working knowledge of practical aspects involved in the installation, setup, repair and maintenance of both commercial and home-built instrumentation has been demonstrated. Experience with commercial instrumentation includes Veeco, Nanonis, Nanosurf, and Createc SPM systems. Extensive involvement in a variety of cross-disciplinary, collaborative ventures has provided insight into the potential advantages, pitfalls and requirements for success. Additional synthetic and analytical techniques include: Electrochemical methods, Optical interferometry; Electron Microscopy; Energy Dispersive X-Ray Analysis (EDAX); Plasma Enhanced Chemical Vapor Deposition (PE-CVD); Nuclear magnetic resonance, atomic absorption, X-Ray fluorescence, mass (SELDI, MALDI, ESI) spectroscopy; Infrared, ATR, Raman and Resonance Raman, Fluorescence, and UV/Visible spectroscopy; gas, high performance, and liquid column chromatography; polyacrylamide, and 2D gel electrophoresis; Southern and Western blot analysis; and cell culturing techniques. Recent Activities: 2008 ICYS-MANA Young Researcher in the CNSI Satellite Research Center for Materials NanoArchitectonics (MANA) in the National Institute of Materials Science (NIMS), Tsukuba, Japan. 2008 Scientific Director of the Sci \| Art Summer Insitute at the University of California - Los Angeles, a two-week immersive course for high-school students with a focus on exposure to nanoscience research and its interface with art, society, and culture. 2008 Member of design team for 'Blue Morph', an interactive Art\|Sci collaboration at the Fringe Gallery, Los Angeles. 2006 Research fellowship at Kumamoto University, Japan, investigating controlled assembly of organic molecules at the solid-liquid interface by electrochemical scanning tunneling microscopy. Advisor: Dr. Masashi Kunitake. 2005 Research internship at IBM Almaden Research Center investigating magnetic resonance force microscopy (MRFM) and its application in the detection of single nuclear spins. Advisor: Dr. Dan Rugar 2004 Member of California Nanosystems Institute Outreach Program 2003 Member of design team for Nano, a collaborative art-science exhibition at the Los Angeles County Museum of Art Employment Experience: Nano & Pico Characterization Laboratory @ the California NanoSystems Institute - UCLA 2008-present Scientific Director Current work involves the ongoing oversight of the open-access user facility in addition to providing consultation services for prospective users in order to maximize the quality and efficiency of experimental analyses. Ongoing research activites continue to include development and application of instrumentation toward understanding the fundamental properties of matter at the nanoscale. Nano & Pico Characterization Laboratory @ the California NanoSystems Institute - UCLA 2007-2008 Technical Director Oversaw the setup and operations of an 1800 sq.ft open-access, multi-user facility focused on materials characterization through Scanning Probe Microscopy. Responsibilities included the acquisition and installation of instrumentation, user training, and preparation of associated materials including experimental protocols and technical documentation. University of California - Los Angeles 2001-2007 Graduate Researcher "From the Bottom Up: Instrument Design and Nanoscale Studies with Electrochemical Scanning Probe Microscopy". Doctoral thesis research involved instrumentation development, specifically the application of a home-built electrochemical SPM toward the investigation of redox active molecular and biological systems at the solid-liquid interface. STM and non-contact AFM analysis enabled quantitative measurements of structural, electronic, and mechanical properties on a wide range of surfaces and adsorbates. Advisor: James K. Gimzewski Matritech Inc., Newton, MA 2000-2001 Research Associate II Carried out proteomic investigations of isolated blood serum proteins as possible screening and diagnostic tools for the early detection of cancer by mass spectrometry. Isolated and characterized protein markers for both cancer of the prostate and bladder. Nelson's Ltd. Wimbledon, UK 1999 Regulatory Affairs Officer Generated a searchable database of reference literature on pharmaceutical products for regulatory affairs operations in the European Union. Drew University, Madison, NJ 1997-1999 Research Assistant “Synthesis and Characterization of Tin (IV) Complexes as Possible anti-Tumor Agents”. Addressed the application of transition metal complexes as DNA chelation agents as alternatives to cis-platin, a cancer inhibiting compound used in drug combination therapy. Honors Thesis Research. Advisor: Dr. Baldwin King Achievements and honors: 1995 National Merit Scholar 1995 USAF student/athlete of the year 2001 UCLA President's Fellowship 2002 UCLA Department of Chemistry Excellence in Teaching Award 2003 NSF-IGERT Fellowship Award 2006 NSF/JSPS - EAPSI Fellowship Award 2008 Elected member of Executive Committee at the Calfornia NanoSytems Institute - UCLA Publications 10. A.Z. Stieg, C. Skibo, R. Schlittler, V. Langlais, C. Joachim and J.K. Gimzewski. “Direct observation of a single molecular eight-state conformational switch” In Preparation (2008) 9. "Conformation dependent molecular pinning through rotation of a single bond" A.Z. Stieg, C. Skibo, R. Schlittler, C. Joachim and J.K. Gimzewski. In Preparation (2008) 8. "A flexible, new electrochemical scanning tunneling microscope for nanoscale studies at the solid-liquid interface" A.Z. Stieg and J.K. Gimzewski. Review of Scientific Instruments 79 (2008). 7. "Folding a polyrotaxane using secondary supramolecular interactions" W. Zhang, W. R. Dichtel, A.Z. Stieg, D. Benitez, J.K. Gimzewski, J.R. Heath, and J.F. Stoddart. Proceedings of the National Acedemy of Sciences 105, 6514-9 (2008). 6. "Observations of Image Contrast and Dimerization of Decacyclene by Low Temperature Scanning Tunneling Microscopy" Lisa Wesoloski, Adam Stieg, Masashi Kunitake, Shane Dultz, James K. Gimzewski. The Journal of Chemical Physics 127, 174703 (2007). 5. "A vertical inertial sliding drive for coarse motion and fine approach in scanning probe microscopy" A. Z. Stieg, P.Wilkinson, and J.K.Gimzewski. Review of Scientific Instruments 78, 036110 (2007). 4. “Identification and preliminary clinical evaluation of a 50.8-kDa serum marker for prostate cancer” Hlavaty John J; Partin Alan W; Shue Matthew J; Mangold LeslieA; Derby Jennifer; Javier Teofilo; Kelley Shane; Stieg Adam; Briggman Joseph V;Hass G Michael; Wu Ying-Jye. Urology 61(6), 1261-5 (2003). 3. “Mass Spectroscopy as a Discovery Tool for Identifying Serum Markers for Prostate Cancer” John J. Hlavaty, Alan W. Partin, Felicity Kusinitz, Matthew J.Shue, Adam Z. Stieg, Kate Bennett and Joseph V. Briggman. Clinical Chemistry 47: 1924-1926, (2001). 2. “Detection of Early Stage Cancer by Serum Protein Analysis” J. Briggman, B.Watkins, J. Hlavaty, A. Stieg, S. Ball. American Laboratory, 33, 32-36 (2001). 1. “Synthesis and Characterization of Tin (IV) Complexes as Possible anti-Tumor Agents” A. Stieg. Honors Thesis, Drew University Library (1999). Selected Posters and Talks 11. “Nanomechanics in Medicine: AFM-based analysis of cancer & green tea extract (GTE)-induced anticancer properties” Keynote Lecture: CNSI-CNBI Symposium on NanoBioTechnology, Tokyo University, Japan (2008) 10. “Toward imaging molecular motion and interaction by scanning probe microscopy” Invited Talk: CNSI/G-COE Symposium, Kyushu University, Japan (2008) 9. "Integrated Nanoscale Science: Synergistic Approaches to Interfaces" Invited Talk Global Challenges - How can Nanotechnology Help? Venice, Italy (2008). 8. "Nanoscale Science and the Interface with Nature" Invited Talk NSF-MEXT US-Japan Exchange Symposium, Los Angeles, CA (2008). 7. "High Performance Imaging and Spectroscopy on Living Systems" CNSI-CNBI Symposium, Los Angeles, CA (2008). 6. "Convergent Synthesis of Mechanically Interlocked Compounds using Click Chemistry" Frontiers of Nanoscience, Snowbird, UT (2007). 5. "Dimerization of Decacylene on Copper Surfaces" ACS Spring National Meeting & Exposition, Chicago, IL (2007). 4. "From the Bottom Up: Instrument Design and Nanoscale Studies with Electrochemical Scanning Probe Microscopy" Invited Talk - Applied Chemistry, Kumamoto University, Japan (2006). 3. "Nanoscale Studies of Molecular Machines by Electrochemical Scanning Tunneling Microscopy" NSF-JSPS EAPSI Symposium, Tokyo, Japan (2006). 2. "Emerging Microscopic Techniques: Probing Matter at the Nanoscale and Beyond" NSF-IGERT Materials Creation Training Program Symposium, Los Angeles, CA (2005). 1. "Templated Electrochemical Nanopatterning: Influence of Deposition Parameters on Morphology and Future Investigations by in-situ STM" 206th meeting of the Electrochemical Society, Honolulu,HI (2004).