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James
U. Bowie
Associate Professor Protein folding and structure; Sequence determinants of protein structure are explored by a combination of genetic, biophysical, and computational approaches |
Office
- (310) 206-4747 |
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Guillaume
Chanfreau
Assistant Professor RNA processing and metabolism in eukaryotes; RNA-Protein interactions; RNA endonucleases |
Office
- (310) 825-4399 |
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Catherine
F. Clarke |
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Steven
G. Clarke
Professor Protein methylation reactions in eukaryotic cells; non-enzymatic degradation reactions of proteins; biochemistry of aging; signal transduction |
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Robert
T. Clubb
Assistant Professor Structural studies of proteins and protein complexes using heteronuclear multidimensional NMR spectroscopy; Biochemical characterization of proteins involved in DNA recombination and repair
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Albert
J. Courey
Professor Transcriptional regulation; biochemical and molecular genetic analysis of pattern formation during fruit fly embryogenesis |
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Richard
E. Dickerson
Professor X-ray studies of nucleic acids and proteins; sequence/structure relationships in double-helical DNA; binding of anti-tumor drugs and recognition proteins to DNA; evolution of macromolecules and metabolic pathways
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David
S. Eisenberg
Professor Study of biochemical macromolecules by X-ray diffraction and computational methods; structure and action of enzymes and of membrane-related proteins; protein folding and the atomic basis of biological recognition |
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Juli
Feigon
Professor Conformational studies of nucleic acids using multidimensional NMR techniques: DNA triplexes and quadruplexes; drug-DNA complexes, DNA and RNA aptamers; DNA and RNA-protein complexes
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Office
- (310) 206-6922
Lab - (310) 825-9232 Fax - (310) 825-0982 256 Boyer Hall feigon@mbi.ucla.edu |
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James
W. Gober
Associate Professor Transcriptional regulation during cell differentiation in Caulobacter; genetics and biochemistry of cell cycle and polar gene expression; DNA higher-order structure and transcriptional activation; chromosome structure |
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Jay
D. Gralla
Professor The role of nucleic acid-protein complexes in cellular controls; repression and activation of transcription; mechanism of action of anti-cancer drugs that attack DNA; chemical probes of DNA structure
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Office
- (310) 825-1620 |
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Wayne
L. Hubbell
Professor Molecular mechanisms of membrane transduction and switching processes, primarily visual transduction and voltage dependent membrane gating systems. Development of spectroscopic approaches for the study of membrane structure, dynamics and electrostatic phenomena |
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Carla
M. Koehler
Assistant Professor Genetic and biochemical studies of protein import into mitochondria, role of mitochondrial biogenesis in cellular functions and disease
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Office
- (310) 794-4834 |
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Christopher
J. Lee
Assistant Professor Bioinformatics and genomics: genome sequence analysis; computational methods for identification of single nucleotide polymorphisms; genomics databases; prediction of protein structure and function |
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Joseph
A. Loo
Professor Development of novel bioanalytical methods for the characterization of proteins and their post-translational modifications and their application for drug discovery and proteomics. Development and application of electrospray ionization mass spectrometry for the study of noncovalently-bound macromolecular complexes and their interactions with inhibitors. Fundamentals of analytical chemistry and mass spectrometry. |
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Harold
G. Martinson
Professor Mechanism of cleavage and polyadenylation of pre-mRNA and its role in signaling transcription termination in eukaryotic cells
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Sabeeha
Merchant
Professor Copper and iron homeostasis; re-modelling of the photosynthetic apparatus in iron-deficiency; mechanisms of copper sensing and signal transduction; cytochrome c biogenesis; chloroplast metabolism; photosynthesis |
Office
- (310) 825-8300 |
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Emil
Reisler |
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Joan
S. Valentine
Professor Bioinorganic chemistry study of the reactivity and other properties of transition metal complexes that are analogues of metalloenzyme active sites; study of structure-function relationships in the enzyme copper-zinc superoxide dismutase using site-directed mutagenesis; biochemistry of oxygen, superoxide, and peroxide |
Office
- (310) 825-9835 |
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Richard
L. Weiss
Professor Compartmentation of enzymes and metabolites; molecular genetics, metabolic and genetic regulation in eukaryotic microorganisms |
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Todd
O. Yeates |
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Emeriti
Faculty
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Daniel
E. Atkinson
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Office
- (310) 825-1159 |
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Paul
D. Boyer |
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Verne
N. Schumaker
Emeritus Professor Surface architecture of serum lipoproteins using monoconal antibodies, and the structure of the gene coding for apolipoprotein B; mechanism of activation of the first component of complement, and the role of segmental flexibility in the immune system; expression of complement proteins |
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Charles
A. West
Emeritus Professor Plant biochemistry; regulation of the biosynthesis of isoprenoid compounds with physiological activity including disease resistance agents and the gibberellin family of growth regulators; diterpene metabolism, studies of molecular mechanisms involved in plant disease resistance |
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