ROBIN L. GARRELL  Professor of Chemistry & Biochemistry, Univiersity of California, Los Angeles  BIOGRAPHICAL SKETCH Robin L. Garrell received her B.S. degree in Biochemistry with Honors and Distinction from Cornell University in 1978, and Ph.D. in Macromolecular Science and Engineering from the University of Michigan in 1984. She was an Assistant Professor on the faculty of the University of Pittsburgh until 1991, when she joined the faculty of the Department of Chemistry and Biochemistry at the University of California, Los Angeles. At UCLA, she is the elected Chair of the Faculty of The College of Letters and Science, Associate Director of the Institute for Cell Mimetics in Space Exploration (CMISE), member of the Biomedical Engineering faculty, and member of the UCLA NSF-IGERT Materials Creation Training Program and Chemistry-Biology Interface Training Program Executive Boards. She currently serves on numerous journal Editorial Advisory Boards and on the NIH Bioanalytical Chemistry, Chemistry and Biophysics Study Section. Garrell was 1999 President of the Society for Applied Spectroscopy. She is the recipient of the National Science Foundation Presidential Young Investigator Award, Herbert Newby McCoy Award for Outstanding Research at UCLA, Iota Sigma Pi Agnes Fay Morgan Award, Hanson-Dow Award for Teaching Excellence at UCLA, and the UCLA Distinguished Teaching Award. She is a Fellow of the American Association for the Advancement of Science. Garrell's research interests span bioanalytical and surface chemistry, with an emphasis fundamentals and applications of adhesion and wetting.

MAIN RESEARCH TOPIC(S) Chemistry of surfaces and films; microfluidics, and biosensors.

RESEARCH DESCRIPTION  Garrell's research objectives are to understand and control adhesion and slip at solution-solid interfaces, and the structure of biological molecules at interfaces. Experiments and theory are being used to characterize the chemical factors responsible for adsorption and adhesion, the structure and mechanical properties of nanoscale films, and how interface chemistry and texture influence wetting and liquid flow. Current areas of investigation include: (1) the structure and stability of organic and inorganic self-assembled monolayers at solution-gold interfaces; (2) the chemistry of cohesion and adhesion in marine biopolymers, and use of these materials to pattern cells for artificial tissues and bioreactors; (3) spectroscopic methods for characterizing protein structure in films, membranes, and drug discovery applications; (4) electrowetting on dielectric surfaces, and applications of electrowetting and surface texturization in microfluidics for biosensors and proteomics.

GARRELL LAB/GROUP WEBSITE Robin Garrell Research Group

Wheeler AR, Moon H, Bird CA, Loo RRO, Kim CJ, Loo JA, Garrell RL "Digital microfluidics with In-line Sample Purification for Proteomics Analyses with MALDI-MS" Anal.,Chem., 2005, 77, 534-540. Garrell RL "Self-Assembled Monolayers of Cystine on Gold"  Abst. Papers Amer. Chem. Soc., 2004, 227,: U853-U853 307-COLL Part 1. Wheeler AR, Moon H, Kim CJ, et al. "Electrowetting-Based Microfluidics for Analysis of Peptides and Proteins by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry" Anal. Chem., 2004, 76, 4833-4838. Garrell RL "Synergy of electrochemistry, SERS and computational methods in understanding the structure and stability of self-assembled" Abstracts of Papers of The American Chemical Society, 2003, 225, U666-U666 379-COLL Part 1. Huang, J.; Egan, V.; Guo, H.; Yoon, J.-Y.; Briseno, A. L.; Garrell, R. L.; Knobler, C. M.; Zhou, F.; Kaner, R. B. "Enantioselective Discrimination of D- and L-Phenylalanine by Chiral Polyaniline Films," Adv. Mater., 2003, 15, 1158-1161. Yoon, J.-Y.; Kim, C.-J.; Garrell, R. L. "Preventing Biomolecular Adsorption in Electrowetting-Based Biofluidic Chips," Anal. Chem., 2003, 75 5097-5102 Nishimura, I.; Garrell, R. L.; Hedrick, M.; Iida, K.; Osher, S.; Wu, B. "Precursor Tissue Analogues (PA) as A Tissue Engineering Strategy," Tissue Engineering, 2003, 9, 77-89. Garrell, R.L.; Houk, K.N. "Ahi Tuna Sashimi Napolean," in What's Cooking in Chemistry: How Leading Chemists Succeed in the Kitchen, ed. Bell, H.P.; Feurstein, T.; Günther, C.T., Hölsken, S. and Lohmann, J.K. (Wiley VCH, New York 2003) pp.67-71. Shapiro, B.; Moon, H.; Garrell, R.; Kim, C.-J.; "Equilibrium Behavior of Sessile Drops under Surface Tension, Applied External Fields, and Material Variations," J. Appl. Phys., 2003, 93, 5794-5811. Shapiro, B.; Moon, H.; Garrell, R.; Kim, C.-J. "Modeling of Electrowetted Surface Tension for Addressable Microfluidic Systems: Dominant Physical Effects, Material Dependences and Limiting Phenomena," MEMS 2003, paper MP44. Moon, H; Cho, SK; Garrell, RL; Kim, CJ. "Low voltage electrowetting-on-dielectric" J. Appl. Physics, 2002, V92, 4080-4087. Chiu, SH; Rowan, SJ; Cantrill, SJ; Ridvan, L; Ashton, PR; Garrell, RL; Stoddart, JF. "Making molecular-necklaces from rotaxanes" Tetrahedron, 2002, V58, 807-814.

Total Robin L. Garrell Publications

GARRELL GROUP/LAB: Robin Garrell Research Group

CONTACT INFORMATION Department of Chemistry & Biochemistry UCLA Box 951569 Los Angeles, CA 90095-1569 tel. (310) 825-2496 fax. (310) 206-2061 garrell@chem.ucla.edu Departmental Website: http://www.chem.ucla.edu