170. Enantioselective Nickel-Catalyzed Mizoroki–Heck Cyclization of Amide Electrophiles

ABSTRACT PDF Supporting Information

Ana S. Bulger,† Daniel J. Nasrallah,† Arismel Tena Meza,† and Neil K. Garg. Chem. Sci. 2024, 15, 2593–2600.



169. Hydration of Nitriles to Primary Amides Enabled by the Ghaffar-Parkins Catalyst

Daniel W. Turner, Allison T. Hands, and Neil K. Garg. Org. Synth. 2023, Manuscript Submitted.

167. Nickel-Catalyzed Amination of Aryl Chlorides

Abstract PDF

Zachary G. Walters, Daniel W. Turner, and Neil K. Garg. Org. Synth. 2024, 101, 150–163.

151. Merging Metals and Strained Intermediates

Abstract PDF

Katie A. Spence,† Arismel Tena Meza,† and Neil K. Garg. Chem Catalysis 2022, 2, 1870–1879.

149. π-Extension of heterocycles via a Pd-catalyzed heterocyclic aryne annulation: π-extended donors for TADF emitters

Abstract PDF

Katie A. Spence,† Jason V. Chari,† Mattia Di Niro, Robert B. Susick, Narcisse Ukwitegetse, Peter I. Djurovich, Mark E. Thompson, and Neil K. Garg. Chem. Sci. 2022, 13, 5884–5892.

144. Synthesis of Phenanthridinones via the Palladium-Catalyzed Annulation of Benzyne

Abstract PDF

Dominick C. Witkowski, Luca McDermott, and Neil K. Garg. Org. Synth. 2022, 99, 159–173.

143. Synthesis of Carboxylic Acids from Benzamide Precursors Using Nickel Catalysis

Abstract PDF

Ana S. Bulger, Dominick C. Witkowski, and Neil K. Garg. Org. Synth. 2022, 99, 305–325.

139. Palladium-Catalyzed Annulations of Strained Cyclic Allenes

Abstract PDF Supporting Information

Andrew V. Kelleghan, Dominick C. Witkowski, Matthew S. McVeigh, Neil K. Garg. J. Am. Chem. Soc. 2021, 143, 25, 9338–9342.

138. A Platform for On-the-Complex Annulation Reactions with Transient Aryne Intermediates

Abstract PDF Supporting Information

Jason V. Chari,† Katie A. Spence,† Robert B. Susick, and Neil K. Garg. Nat. Commun. 2021, 12, 3706.

135. Palladium-Catalyzed Acetylation of Arylbromides

Abstract PDF

Milauni M. Mehta, Andrew V. Kelleghan, and Neil K. Garg. Org. Synth. 2021, 98, 68-83

131. Reductive Arylation of Amides via a Nickel‐Catalyzed Suzuki–Miyaura Coupling and Transfer Hydrogenation Cascade

Abstract PDF Supporting Information

Timothy Boit,† Milauni M. Mehta,† Junyong Kim, Emma L. Baker, and Neil K. Garg. Angew. Chem., Int. Ed. 2021, 60, 2472–2477

130. Activation of C–O and C–N Bonds Using Non-Precious-Metal Catalysis

Abstract PDF

Timothy Boit,† Ana, S. Bulger,† Jacob E. Dander,† and Neil K. Garg. ACS Catalysis 2020, 10, 12109–12126.

128. Intercepting Fleeting Cyclic Allenes with Asymmetric Nickel Catalysis

Abstract PDF Supporting Information C&E News SYNFACTS HIGHLIGHT

Michael M. Yamano,† Andrew V. Kelleghan,† Qianzhen Shao,† Maude Giroud, Bryan J. Simmons, Bo Li, Shuming Chen, K. N. Houk, and Neil K. Garg. Nature 2020, 586, 242–247.

119. Nickel-Catalyzed Conversion of Amides to Carboxylic Acids

Abstract PDF Supporting Information Chemistry Views OPR&D Highlights Organic Chemistry Portal Organic Chemistry Portal – Functional Group Protection

Rachel R. Knapp, Ana S. Bulger, and Neil K. Garg. Org. Lett. 2020, 22, 2833–2837.

115. Ni-Catalyzed Suzuki–Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop

Abstract PDF Supporting Information

Milauni M. Mehta,† Timothy B. Boit,† Jacob E. Dander,† and Neil K. Garg. Org. Lett. 2020, 22, 1–5. 

112. Synthesis of Triphenylene via the Palladium-catalyzed Annulation of Benzyne

Abstract PDF

Katie A. Spence, Milauni M. Mehta, and Neil K. Garg. Org. Synth. 2022, 99, 174–189.

109. Chemoenzymatic Conversion of Amides to Enantioenriched Alcohols in Aqueous Medium

Abstract PDF Supporting Information Nature Chemistry Community

Jacob E. Dander, Maude Giroud, Sophie Racine, Evan R. Darzi, Oscar Alvizo, David Entwistle, and Neil K. Garg. Communications Chemistry 2019, 2, 82.

106. Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes

Abstract PDF Supporting Information

Michael M. Yamano, Rachel R. Knapp, Aurapat Ngamnithiporn, Melissa Ramirez, Kendall N. Houk,* Brian M. Stoltz,* and Neil K. Garg. Angew. Chem., Int. Ed. 2019, 58, 5653–5657.

104. Breaking Amide C–N Bonds in an Undergraduate Organic Chemistry Laboratory

Abstract PDF Supporting Information

Jacob E. Dander, Lucas A. Morrill, Melinda M. Nguyen, Shuming Chen, and Neil K. Garg. J. Chem. Ed. 2019, 96, 776–780.

103. Facile Reduction of Amides Using Nickel Catalysis: Reduction of 12-Aminododecanolactam

Abstract PDF

Bryan J. Simmons, Melissa Ramirez, and Neil K. Garg. Org. Synth. 2019, 96, 436–454.

101. Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor

Abstract PDF Supporting Information

Alexander Tuan-Huy Duong, Bryan J. Simmons, Mohammad Parvez Alam, Jesus Campagna, Neil K. Garg, Varghese John. Tetrahedron Lett. 2019, 60, 322–326.

99. Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho Substituted Biaryl Synthesis.

Abstract PDF Supporting Information

Nitinchandra Dahyabhai Patel, Joshua D. Sieber, Sergei Tcyrulnikov, Bryan J. Simmons, Daniel Rivalti, Krishnaja Duvvuri, Yongda Zhang, Donghong A. Gao, Keith R. Fandrick, Nizar Haddad, Kendricks So Lao, Hari Prasad Reddy Mangunuru, Soumik Biswas, Bo Qu, Nelu Grinberg, Scott Pennino, Heewon Lee, Jinhua J. Song, B. Frank Gupton, Neil K. Garg, Marisa C. Kozlowski, and Chris H. Senanayake. ACS Catal. 2018, 8, 10190–10209.

91. Nickel-Catalyzed Suzuki–Miyaura Coupling of Aliphatic Amides

Abstract PDF Supporting Information SYNFACTS HIGHLIGHT

Timothy B. Boit,† Nicholas A. Weires,† Junyong Kim,† and Neil K. Garg. ACS Catal. 2018, 8, 1003–1008.

90. Nickel-Catalyzed Transamidation of Aliphatic Amide Derivatives

Abstract PDF Supporting Information

Jacob E. Dander,† Emma L. Baker,† and Neil K. Garg. Chem. Sci. 2017, 8, 6433–6438.

83. Enantioselective Nickel-Catalyzed Mizoroki–Heck Cyclizations to Generate Quaternary Stereocenters

Abstract PDF Supporting Information

Jean-Nicolas Desrosiers, Jialin Wen, Sergei Tcyrulnikov, Soumik Biswas, Bo Qu, Liana Hie, Dmitry Kurouski, Ling Wu, Nelu Grinberg, Nizar Haddad, Carl A. Busacca, Nathan K. Yee, Jinhua J. Song, Neil K. Garg, Xumu Zhang, Marisa C. Kozlowski, and Chris H. Senanayake. Org. Lett. 2017, 19, 3338–3341.

82. Kinetic Modeling of the Nickel-Catalyzed Esterification of Amides

Abstract PDF Supporting Information C&E News ACS Editor’s Choice (June 4, 2017)

Nicholas A. Weires, Daniel D. Caspi, and Neil K. Garg. ACS Catal. 2017, 7, 4381–4385.

78. Nickel-Catalyzed Reduction of Secondary and Tertiary Amides

Abstract PDF Supporting Information Organic Chemistry Portal

Bryan J. Simmons, Marie Hoffmann, Jaeyeon Hwang, Moritz K. Jackl, and Neil K. Garg. Org. Lett. 2017, 19, 1910–1913.

75. Breaking Amides Using Nickel Catalysis

Abstract PDF

Jacob E. Dander and Neil K. Garg. ACS Catal. 2017, 7, 1413–1423.

72. Nickel-Catalyzed Esterification of Aliphatic Amides

Abstract PDF Supporting Information

Liana Hie,† Emma L. Baker,† Sarah M. Anthony, Jean-Nicolas Desrosiers, Chris Senanayake, and Neil K. Garg. Angew. Chem. Int. Ed. 2016, 55, 15129–15132.

81. Mizoroki–Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers

Abstract PDF Supporting Information

Jose M. Medina,† Jesus Moreno,† Sophie Racine, Shuaijing Du, and Neil K. Garg. Angew. Chem., Int. Ed. 2017, 56, 6567–6571.

71. Nickel-Catalyzed Suzuki-Miyaura Coupling in t-Amyl Alcohol for the Preparation of 5-(Furan-3-yl)pyrimidine

Abstract PDF

Liana Hie and Neil K. Garg. Org. Synth. 2016, 93, 306–318.

69. Construction of Quaternary Stereocenters via Nickel-Catalyzed Heck Cyclizations

Abstract PDF Supporting Information

Jean-Nicolas Desrosiers, Liana Hie, Soumik Biswas, Olga V. Zatolochnaya, Sonia Rodriguez, Heewon Lee, Nelu Grinberg, Nizar Haddad, Nathan K. Yee, Neil K. Garg, and Chris H. Senanayake. Angew. Chem. Int. Ed. 2016, 55, 11921–11924

68. Benchtop Delivery of Ni(cod)2 using Paraffin Capsules

Abstract PDF Supporting Information

Jacob E. Dander,† Nicholas A. Weires,† and Neil K. Garg. Org. Lett. 2016, 18, 3934–3936

67. A Two-Step Approach to Achieve Secondary Amide Transamidation Enabled by Nickel Catalysis

Abstract PDF Supporting Information

Emma L. Baker, Michael M. Yamano, Yujing Zhou, Sarah M. Anthony, and Neil K. Garg. Nat. Commun. 2016, 7, 1–5

66. Nickel-Catalyzed Alkylation of Amide Derivatives

Abstract PDF Supporting Information

Bryan J. Simmons,† Nicholas A. Weires,† Jacob E. Dander, and Neil K. Garg. ACS Catal. 2016, 6, 3176–3179

60. Nickel-Catalyzed Activation of Acyl C–O Bonds of Methyl Esters

Abstract PDF Supporting Information

Liana Hie, Noah F. Fine Nathel, Xin Hong, Yun-Fang Yang, K. N. Houk, and Neil K. Garg. Angew. Chem. Int. Ed. 2016, 55, 2810–2814

59. Nickel-Catalysed Suzuki–Miyaura Coupling of Amides

Abstract PDF Supporting Information C&E News C&E News Top Research of 2015

Nicholas A. Weires, Emma L. Baker and Neil K. Garg. Nat. Chem. 2016, 8, 75–79

57. Conversion of Amides to Esters by the Nickel-Catalysed Activation of Amide C–N Bonds

Abstract PDF Supporting Information C&E News Nat. Chem. Highlight Angew. Chem. Int. Ed. Highlight Synform C&E News Top Research of 2015 Org. Chem. Highlights

Liana Hie, Noah F. Fine Nathel, Tejas K. Shah, Emma L. Baker, Xin Hong, Yun-Fang Yang, Peng Liu, K. N. Houk, and Neil K. Garg. Nature 2015, 524, 79–83

46. Nickel-Catalyzed Amination of Aryl Chlorides and Sulfamates in 2-Methyl-THF

Abstract PDF Supporting Information C&E News

Noah F. Fine Nathel, Junyong Kim, Liana Hie, Xingyu Jiang, and Neil K. Garg. ACS Catal. 2014, 4, 3289–3293

45. Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling in a Green Alcohol Solvent for an Undergraduate Organic Chemistry Laboratory

Abstract PDF Supporting Information

Liana Hie, Jonah J. Chang, and Neil K. Garg. J. Chem. Educ. 2015, 92, 571–574

40. Palladium-Catalyzed Acetylation of Arenes

Abstract PDF Supporting Information C&E News Organic Chemistry Portal

Stephen D. Ramgren and Neil K. Garg. Org. Lett. 2014, 16, 824–827

38. Nickel-Catalyzed Suzuki-Miyaura Coupling in Green Solvents

Abstract PDF Supporting Information Nexus Newsletters

Stephen D. Ramgren, Liana Hie, Yuxuan Ye, and Neil K. Garg. Org. Lett. 2013, 15, 3950–3953

35. Synthesis of Diphenylhexatriene by the Pd-Catalyzed Dimerization of Cinnamyl Acetate

Abstract PDF Supporting Information

Tehetena Mesganaw, G.-Yoon J. Im, and Neil K. Garg. J. Org. Chem. 2013, 78, 3391–3393

33. Ni- and Fe-Catalyzed Cross-Coupling Reactions of Phenol Derivatives

Abstract PDF

Tehetena Mesganaw and Neil K. Garg. Org. Process Res. Dev. 2013, 17, 29–39

29. Nickel-Catalyzed Amination of Aryl Sulfamates and Carbamates Using an Air-Stable Precatalyst

Abstract PDF Supporting Information

Liana Hie, Stephen D. Ramgren, Tehetena Mesganaw, and Neil K. Garg. Org. Lett. 2012, 14, 4182–4185

28. Iron-Catalyzed Alkylations of Aryl Sulfamates and Carbamates

Abstract PDF Supporting Information Synfacts Highlight | Organic Chemistry Portal

Amanda L. Silberstein, Stephen D. Ramgren, and Neil K. Garg. Org. Lett. 2012, 14, 3796–3799

27. Cine Substitution of Arenes Using the Aryl Carbamate as a Removable Directing Group

Abstract PDF Supporting Information

Tehetena Mesganaw, Noah F. Fine Nathel, and Neil K. Garg. Org. Lett. 2012, 14, 2918–2921

20. Nickel-Catalyzed Amination of Aryl Carbamates and Sequential Site-Selective Cross-Couplings

Abstract PDF Supporting Information

Tehetena Mesganaw, Amanda L. Silberstein, Stephen D. Ramgren, Noah F. Fine Nathel, Xin Hong, Peng Liu, and Neil K. Garg. Chem. Sci. 2011, 2, 1766–1771

18. Suzuki–Miyaura Cross-Coupling of Aryl Carbamates and Sulfamates: Experimental and Computational Studies

Abstract PDF Supporting Information Synfacts Highlight

Kyle W. Quasdorf, Aurora Antoft-Finch, Peng Liu, Amanda L. Silberstein, Anna Komaromi, Tom Blackburn, Stephen D. Ramgren, K. N. Houk, Victor Snieckus, and Neil K. Garg. J. Am. Chem. Soc. 2011, 133, 6352–6363

14. Nickel-Catalyzed Amination of Aryl Sulfamates

Abstract PDF Supporting Information Synfacts Highlight

Stephen D. Ramgren, Amanda L. Silberstein, Yang Yang, and Neil K. Garg. Angew. Chem. Int. Ed. 2011, 50, 2171–2173

13. Nickel-Catalyzed Cross-Couplings Involving Carbon–Oxygen Bonds

Abstract PDF

Brad M. Rosen, Kyle W. Quasdorf, Daniella A. Wilson, Na Zhang, Ana-Maria Resmerita, Neil K. Garg, and Virgil Percec. Chem. Rev. 2011, 111, 1346–1416 (invited contribution)

10. Bis(tricyclohexylphosphine)dichloronickel

Abstract PDF

Kyle W. Quasdorf and Neil K. Garg. Encyclopedia of Reagents for Organic Synthesis, 2010 (invited contribution)

6. Suzuki–Miyaura Coupling of Aryl Carbamates, Carbonates, and Sulfamates

Abstract PDF Supporting Information Synfacts Highlight

Kyle W. Quasdorf, Michelle Riener, Krastina V. Petrova, and Neil K. Garg. J. Am. Chem. Soc. 2009, 131, 17748–17749

1. Cross-Coupling Reactions of Aryl Pivalates with Boronic Acids

Abstract PDF Supporting Information Synfacts Highlight

Kyle W. Quasdorf, Xia Tian, and Neil K. Garg. J. Am. Chem. Soc. 2008, 130, 14422–14423