Publications from the Jung Group
1. G. Stork, and M. E. Jung,
"Vinylsilanes as Carbonyl Precursors. Use in Annelation Reactions," J.
Am. Chem. Soc. 1974, 96, 3682-3684. [pdf]
2. G. Stork, M. E. Jung, E. Colvin,
and Y. Noel, "Synthetic Routes to Halomethyl Vinylsilanes," J. Am.
Chem. Soc. 1974, 96, 3684-3686. [pdf]
3. M.E. Jung, "I. Trans,
trans-1,4-Diacetoxy-2-Methyl-1,3-Butadiene. A Possible Starting
Material for Tetrodotoxin; II. Vinylsilanes as Annelation Reagents," Diss.
Abstr. Int. B 1974, 34, 4288. [pdf]
4. M. E. Jung, "Stereoselective
Synthesis of Substituted Functionalized Butadienes," J. Chem. Soc.,
Chem. Commun. 1974, 956-957. [pdf]
5. M. E. Jung, "A Review of
Annulation," Tetrahedron 1976, 32, 3-30. [pdf]
6. M. E. Jung, "Oxidation of
Trimethylsilyl Ethers via Hydride Abstraction: A New Procedure for
Alcohol Oxidation," J. Org. Chem. 1976, 41, 1479-1480. [pdf]
7. M. E. Jung, P. A. Blair, and J.
A. Lowe, "Reactions of Oxime Dianions: Stereospecificity in
Alkylation," Tetrahedron Lett. 1976, 1439-1442. [pdf]
8. M. E. Jung and C. A. McCombs,
"2-Trimethylsilyloxy-1,3-Butadiene. A New Reactive Diene. Preparation
and Reactions," Tetrahedron Lett. 1976, 2935-2938. [pdf]
9. O. L. Chapman, C.-C. Chang, J.
Kolc, M. E. Jung, J. A. Lowe, T. J. Barton, and M. L. Tumey,
"1,1,2-Trimethylsilaethylene," J. Am. Chem. Soc. 1976, 98, 7844-7846. [pdf]
10. M. E. Jung and L. M. Speltz,
"Oxidation of Ethers via Hydride Abstraction: A New Procedure for
Selective Oxidation of Primary, Secondary Diols at the Secondary
Position," J. Am. Chem. Soc. 1976, 98, 7882-7884. [pdf]
11. M. E. Jung and M. A. Lyster,
"Quantitative Dealkylation of Alkyl Esters via Treatment with
Trimethylsilyl Iodide. A New Method for Ester Hydrolysis," J. Am.
Chem. Soc. 1977, 99, 968-969. [pdf]
12. M. E. Jung and J. A. Lowe,
"Synthetic Approaches to Adriamycin Involving Diels-Alder Reactions of
Photochemically Generated Bis-Ketenes: Total Synthesis of Islandicin
and Digitopurpone," J. Org. Chem.
1977, 42, 2371-2373. [pdf]
13. M. E. Jung and P. L. Ornstein,
"A New Method for the Efficient Conversion of Alcohols into Iodides via
Treatment with Trimethylsilyl Iodide," Tetrahedron Lett. 1977, 2659-2662. [pdf]
14. M. E. Jung and J. P. Hudspeth,
"Three-Carbon Annulation. Formation of Five-Membered Rings from Olefins
via Diels-Alder Reaction," J. Am. Chem. Soc. 1977, 99, 5508-5510. [pdf]
15. M. E. Jung and T. J. Shaw,
"Stereospecificity in Alkylation of Anions of Ketone
Dimethylhydrazones: Kinetic Anti Preference, Thermodynamic Syn
Preference," Tetrahedron Lett. 1977, 3305-3308. [pdf]
16. M. E. Jung and R. B. Blum,
"Generation of the Enolate of Acetaldehyde from Non-Carbonyl Substances
and its C-Alkylation, O-Acylation, and O-Silylation," Tetrahedron
Lett. 1977, 3791-3794. [pdf]
17. M. E. Jung and M. A. Lyster,
"Quantitative Dealkylation of Alkyl Ethers via Treatment with
Trimethylsilyl Iodide. A New Method for Ether Hydrolysis," J. Org.
Chem. 1977, 42, 3761-3764. [pdf]
18. M. E. Jung, W. A. Andrus, and
P. L. Ornstein, "Non-Aqueous Conversion of Ketals to Ketones via
Treatment with Trimethylsilyl Iodide," Tetrahedron Lett. 1977, 4175-4178. [pdf]
19. M. E. Jung, Y.-G. Pan, M. W.
Rathke, D. F. Sullivan, and R. P. Woodbury, "Oxidation of Trialkylsilyl
Enol Ethers via Hydride Abstraction: A New Procedure for Ketone to
Enone Conversion," J. Org. Chem. 1977, 42, 3961-3963. [pdf]
20. M. E. Jung and J. A. Lowe,
"Synthetic Approaches to Aclacinomycin and Pyrromycin Antitumor
Antibiotics via Diels-Alder Reactions of 6-Alkoxy-2-pyrones: Total
Synthesis of Chrysophanol, Helminthosporin, and Pachybasin," J.
Chem. Soc., Chem. Commun.
1978, 95-96. [pdf]
21. M. E. Jung and M. A. Lyster,
"Conversion of Alkyl Carbamates to Amines via Treatment with
Trimethylsilyl Iodide," J. Chem. Soc., Chem. Commun. 1978, 315-6. [pdf]
22. M. E. Jung and J. P. Hudspeth,
"Anionic Oxy-Cope Rearrangements with Aromatic Substrates in
Bicyclo[2.2.1]
heptene Systems: Facile Synthesis of cis-Hydrindanone Derivatives,
Including Steroid Analogues," J. Am. Chem. Soc. 1978, 100, 4309-4311. [pdf]
23. M. E. Jung, M. A. Mazurek, and
R. M. Lim, "A New Efficient Synthesis of Iodomethyl Methyl Ether," Synthesis
1978, 588-590. [pdf]
24. M. E. Jung and R. W. Brown,
"Direct Oxidation of Alcohols and Diols via Hydride Abstraction," Tetrahedron
Lett. 1978, 2771-2774. [pdf]
25. M. E. Jung and C. A. McCombs,
"Total Synthesis of (±) Seychellene: Use of Silyloxydienes in
Synthesis," J. Am. Chem. Soc. 1978, 100, 5207-5209. [pdf]
26. M. E. Jung, A. B. Mossman, and
M. A. Lyster, "Direct Synthesis of Dibenzocycloocta-octadienes via
Double Ortho Friedel-Crafts Alkylation by the Use of
Aldehyde-Trimethylsilyl Iodide Adducts," J. Org. Chem. 1978, 43, 3698-3701. [pdf]
27. M. E. Jung and T. A.
Blumenkopf, "Mild Methods for the in situ Generation of Trimethylsilyl
Iodide," Tetrahedron Lett. 1978, 3657-3660. [pdf]
28. M. E. Jung and G. L. Hatfield,
"Preparation of Bromides from Alcohols via Treatment with
Trimethylsilyl Bromide," Tetrahedron Lett. 1978, 4483-4486. [pdf]
29. M. E. Jung and C. A. McCombs,
"2-Trimethylsilyloxy-1,3-butadiene," Organic Syntheses 1978, 58, 163-168. [pdf]
30. M. E. Jung and B. J. Gaede,
"Synthesis and Diels-Alder Reactions of E-1-Trimethylsilyl-1,3-butadiene,"
Tetrahedron 1979, 35, 621-625. [pdf]
31. M. E. Jung, T. J. Shaw, R. R.
Fraser, J. Banville, and K. Taymaz, "Reinvestigation of the
Regioselectivity of Deprotonation of Ketone Dimethylhydrazones," Tetrahedron
Lett. 1979, 4149-4152. [pdf]
32. M. E. Jung and M. A. Lyster,
"The Cleavage of Methyl Ethers, Using Iodotrimethylsilane: Cyclohexanol
from Cyclohexyl Methyl Ether," Organic Syntheses 1979, 59,
35-41. [pdf]
33. M. E. Jung and J. P. Hudspeth,
"Total Synthesis of (±)-Coronafacic Acid: Use of Anionic Oxy-Cope
Rearrangements on Aromatic Substrates in Synthesis," J. Am. Chem.
Soc. 1980, 102, 2463-2464. [pdf]
34. M. E. Jung and T. J. Shaw,
"Total Synthesis of (R)-Glycerol Acetonide and the Anti-epileptic and
Hypotensive Drug, (-)-γ-Amino-β-hydroxybutyric
Acid (GABOB): Use of Vitamin C as a Chiral Starting Material," J.
Am. Chem. Soc. 1980, 102, 6304-6311. [pdf]
35. M. E. Jung and Y.-G. Pan,
"Direct Stereoselective Total Synthesis of (±)-Seychellene," Tetrahedron
Lett. 1980, 21, 3127-3130. [pdf]
36. M. E. Jung and C. D. Radcliffe,
"Total Synthesis of the Sesquiterpene (±)-β-Cuparenone:
Use of Three-Carbon Annulation in Synthesis," Tetrahedron Lett.
1980, 21, 4397-4400. [pdf]
37. M. E. Jung and J. J. Shapiro,
"Synthesis and Structure Determination of 2-Azabicyclo-[2.2.1]hept-2-enes and Their
Derivatives: W Effect on Chemical Shifts," J. Am. Chem. Soc. 1980, 102, 7862-7866. [pdf]
38. M. E. Jung and S. J. Miller,
"Total Synthesis of Isopavine and Intermediates for the Preparation of
Substituted Amitriptyline Analogues: Facile Routes to Substituted
Dibenzocyclooctatrienes and Dibenzocycloheptatrienes," J. Am. Chem.
Soc. 1981, 103, 1984-1992. [pdf]
39. M. E. Jung and K. M. Halweg,
"Intramolecular Lewis-Acid Promoted [2+2] Cycloadditions: An Efficient
Total Synthesis of (±)-Coronafacic Acid via an Internal Diels-Alder
Reaction," Tetrahedron Lett. 1981, 22, 2735-2738. [pdf]
40. M. E. Jung and R. W. Brown,
"Regiospecific Friedel-Crafts Acylation of 6-Alkoxy-2-Pyrones:
Preparation of Substituted Aromatics and Anthraquinones," Tetrahedron
Lett. 1981, 22, 3355-3358. [pdf]
41. M. E. Jung and R. B. Blum,
"Photochemical Transformation of Methoxyphthalaldehydic Esters:
Synthesis of Methyl 6-Methoxyphthalaldehydate from the 3-Methoxy
Isomer," J. Chem. Soc., Chem. Commun. 1981, 962-963. [pdf]
42. M. E. Jung, C. A. McCombs, Y.
Takeda, and Y.-G. Pan, "Use of Silyloxydienes in Synthesis. Total
Syntheses of the Sesquiterpene (±)-Seychellene," J. Am. Chem. Soc. 1981, 103, 6677-6687. [pdf]
43. M. E. Jung and K. M. Halweg,
"Simple Regioselective Synthesis of Trans-7α-Methyl-hydrind-4-en-1-one,
A Key Intermediate for Steroid Total Synthesis," Tetrahedron Lett.
1981, 22, 3929-3932. [pdf]
44. M. E. Jung, K. Shishido, L.
Light, and L. Davis, "Preparation of Di- and Triacylimines and Their
Use in the Synthesis of Nitrogen Heterocycles," Tetrahedron Lett.
1981, 22, 4607-4610. [pdf]
45. M. E. Jung, K. Shishido, and L.
H. Davis, "Simple Syntheses of Diethyl Oxomalonate and Alkyl
Glyoxylates," J. Org. Chem. 1982, 47, 891-892. [pdf]
46. M. E. Jung and L. A. Light,
"Intramolecular Diels-Alder Cycloadditions of Perchloroallyloxy- and
diallyloxycyclopentadienes," J. Org. Chem. 1982, 47, 1084-1087. [pdf]
47. M. E. Jung, M. Node, R.
Pfluger, M. A. Lyster, and J. A. Lowe, III, "Regiospecific Synthesis of
Bicyclic 6-Alkoxy-2-Pyrones and Their Use in the Production of
Tetracyclic Inter-mediates for 11-Desoxyanthracycline Synthesis," J.
Org. Chem. 1982, 47, 1150-1152. [pdf]
48. M. E. Jung and L. A. Light,
"Preparation of Iodoallylic Alcohols via Hydrostannylation:
Spectroscopic Proof of Structures," Tetrahedron Lett. 1982, 23, 3851-3854. [pdf]
49. M. E. Jung and G. L. Hatfield,
"Novel Oxidative Rearrangement of α,β-Unsaturated
Ketone Hydrazones on Iodination in Base," Tetrahedron Lett. 1982, 23, 3991-3994. [pdf]
50. M. E. Jung and P. Lewis,
"Addition of Organocuprates to Aldehydes via their Trimethylsilyl
Iodide Adducts," Synth. Commun. 1983, 13, 213-218. [pdf]
51. M. E. Jung, "New Approaches to
the Total Synthesis of Biologically Active Natural Products," in Current
Trends in Organic Synthesis, IUPAC, ed. H. Nozaki, Pergamon Press,
Oxford, 1983, 61-70. [pdf]
52. M. E. Jung and G. L. Hatfield,
"Synthesis of Syn-7-benzyloxy-4-methylbicyclo[2.2.1]-hept-5-en-2-one,
an Intermediate for the Synthesis of Steroids and Tricothecanes; Tandem
Anionic [1,3]-[3,3] Sigmatropic Rearrangement," Tetrahedron Lett.
1983, 24, 2931-2934. [pdf]
53. M. E. Jung and G. L. Hatfield,
"Facile Synthesis of (3aS)-1,3a-Dimethyl-2,3,3a,5,6,7-hexahydroinden-4(5H)-one,
an Intermediate for Steroid Synthesis," Tetrahedron Lett. 1983, 24, 3175-3178. [pdf]
54. M. E. Jung, J. A. Hagenah, and
Zeng L.-M., "Simple, Stereospecific Preparation of
Z-3-Iodoacrylic Acid from Propiolic Acid and Methylmagnesium Iodide," Tetrahedron
Lett. 1983, 24, 3973-3974. [pdf]
55. M. E. Jung and Zeng L.-M.,
"Reaction of Oximes with Trimethylsilyl Iodide: Dehydration and
Beckmann Rearrangement," Tetrahedron Lett. 1983, 24, 4533-4534. [pdf]
56. M. E. Jung and J. A. Hagenah,
"Mechanism of Bromination of 1,5-Diacetoxynaphthalene," J. Org.
Chem. 1983, 48, 5359-5361. [pdf]
57. M. E. Jung and K. M. Halweg,
"Stereoselectivity in Intramolecular Diels-Alder Reactions: A Short
Total Synthesis of (±)-Estrone," Tetrahedron Lett. 1984, 25, 2121-2124. [pdf]
58. M. E. Jung and J. C. Rohloff,
"Intramolecular Diels-Alder Chemistry of Pyrroles," J. Chem. Soc.,
Chem. Commun. 1984, 630-632. [pdf]
59. M. E. Jung, R. W. Brown, J. A.
Hagenah, and C. E. Strouse, "Cycloadditions of Benzopyrones: Rapid
Access to Bicyclic AB-Ring Analogues of Anthracyclines," Tetrahedron
Lett. 1984, 25, 3659-3662. [pdf]
60. M. E. Jung and L. A. Light,
"Stereospecific Synthesis of Substituted cis-Hydrindan-5-ones and Their
Regiospecific Enolization and Functionalization: Synthetic
Intermediates for Reserpine," J. Am. Chem. Soc. 1984, 106, 7614-7618. [pdf]
61. M. E. Jung, J. A. Lowe, III, M.
A. Lyster, M. Node, R. W. Pfluger, and R. W. Brown, "Regiospecific
Synthesis of Mono- and Bicyclic 6-Alkoxy-2-pyrones and their Use in the
Preparation of Substituted Aromatics, Anthraquinones, and Tetracyclic
Intermediates for 11-Deoxyanthracycline Synthesis," Tetrahedron
Symposium-in-Print No. 17, Tetrahedron 1984, 40, 4751-4766. [pdf]
62. M. E. Jung and L. J. Street,
"Synthetic Studies on the Avermectins: Substituent Effects on
Intramolecular Diels-Alder Reactions of N-Furfuryl Acrylamides and
Further Reactions of the Cycloadducts," J. Am. Chem. Soc. 1984, 106, 8327-8328. [pdf]
63. M. E. Jung, P. S. Y. Lam, M. M.
Mansuri, and L. M. Speltz, "Stereoselective Synthesis of an Analogue of
Podophyllotoxin by an Intramolecular Diels-Alder Reaction," J. Org.
Chem. 1985, 50, 1087-1094. [pdf]
64. M. E. Jung and L. J. Street,
"Novel Rearrangements of 7-Oxanorbornene Systems," Tetrahedron Lett.
1985, 26, 3639-3642. [pdf]
65. M. E. Jung and J. C. Rohloff,
"Organic Chemistry of L-Tyrosine. 1. General Synthesis of Chiral
Piperazines from Amino Acids," J. Org. Chem. 1985, 50, 4909-4913. [pdf]
66. M.
Fintel, G. A. Langer, J. C.
Rohloff, and M. E. Jung, "Contribution of Myocardial Diffuse
Double-layer Calcium to Contractile Function," Am. J.
Physiol. 1985, 249 (Heart Circ. Physiol. 18), H989-H994. [pdf]
68. M. E. Jung, L. J. Street, and
Y. Usui, "Chemoselective Cycloadditions of 3,4-Dialkoxy-furans and
Alkyl Coumalates. Novel Loss of Aromaticity of Two Non-Benzenoid
Aromatic Rings in a Mild Thermal Process," J. Am. Chem. Soc. 1986, 108, 6810-6811. [pdf]
69. M. E. Jung and G. T. Lowen, "A
Direct Synthesis of Trans 2-Arylbenzocyclobutenol, a Potential
Intermediate for Podophyllotoxin Synthesis: Use of LDA for Benzyne
Formation and Trapping," Tetrahedron Lett. 1986, 27, 5319-5322. [pdf]
70. M. E. Jung and K. R. Buszek,
"Alkenylimmonium Salts as Dienophiles in Diels-Alder Cycloadditions
with High Reactivity and Stereoselectivity," Tetrahedron Lett. 1986, 27, 6165-6168. [pdf]
71. M. E. Jung and C.-Y. Liu,
"Efficient Synthesis of a Head-to-head Isoprenoid Geochemical Biomarker
from Phytol,"
J. Org. Chem. 1986, 51, 5446-5447. [pdf]
72. M. E. Jung and J. A. Hagenah,
"Preparation and Cycloaddition of Functionalized
4,6-Dialkylpyrone-5-carboxylates. Synthesis of Bicyclic Lactones and
Substituted Benzoates," Heterocycles 1987, 25, 117-121. [pdf]
73. M. E. Jung and J. A. Hagenah,
"Synthetic Approach to Aklavinone Using 2-Oxo-2H-pyran-5-carboxylate
(Coumalate) Intermediates," J. Org. Chem. 1987, 52, 1889-1901. [pdf]
74. M. E. Jung and D. D. Grove,
"Nitroacetylene Equivalents. Preparation and Cycloadditions of
2-Phenylsulphinyl-1-nitroalkenes," J. Chem. Soc., Chem. Commun.
1987, 753-755. [pdf]
75. M. E. Jung and B. E. Love,
"Syntheses and Properties of Cyclic Keto Alkenylammonium Salts," J.
Chem. Soc., Chem. Commun.
1987, 1288-1289. [pdf]
76. M. E. Jung, D. D. Grove, and S.
I. Khan, "Simple Preparation of α-Acyl
γ-Thioaryl
Oximes (N-Hydroxy 2-Oxoalkanimidothioates); Ambident Reactivity of α-Nitroketones,"
J. Org. Chem. 1987, 52, 4570-4573. [pdf]
77. M. E. Jung, Y. Usui, and C. T.
Vu, "Rapid and Efficient Synthesis of a Fully Functionalized Synthon
for the Bottom Half of the Antiparasitic Agent, Ivermectin," Tetrahedron
Lett. 1987, 28, 5977-5980. [pdf]
78. M. E. Jung and S. Abrecht,
"Improved Synthesis of 3-Substituted 7-Methoxybenzofurans, Useful
Intermediates for the Preparation of Morphine Analogues," J. Org.
Chem. 1988, 53, 423-426. [pdf]
79. M. E. Jung and L. J. Street,
"Synthetic Approach to the Ivermectin Bottom Half Using Internal
Cycloadducts of N-Furfuryl Acrylamides: Functionality and Optical
Activity," Heterocycles
1988, 27, 45-48. [pdf]
80. M. E. Jung and H. Xia,
"Synthesis and Transport Properties of 12-Silacrown-3, a New Type of
Anion Complexing Agent," Tetrahedron Lett. 1988, 29, 297-300. [pdf]
81. M. E. Jung and K. R. Buszek,
"The Stereochemistry of Addition of Trialkylammonium and Pyridinium
Tetrafluoroborate Salts to Activated Acetylenes. Preparation of Novel
Dienophiles for Diels-Alder Reactions," J. Am. Chem. Soc. 1988, 110, 3965-9. [pdf]
82. M. E. Jung and J. Gervay,
"Studies on the Effects of Substituents on Rate Enhancements in
Intramolecular Diels-Alder Reactions: Reasons for the Gem-Dimethyl
Effect," Tetrahedron Lett. 1988, 29, 2429-2432. [pdf]
83. M. E. Jung and Y. H. Jung,
"Total Synthesis of the Aglycone of the 8-Methyl Benzonaphthopyrone
Antibiotics, Gilvocarcin M, Virenomycin M, and Albacarcin M," Tetrahedron
Lett. 1988, 29, 2517-2520. [pdf]
84. M. E. Jung, "Problem Solving in
Organic Synthesis. The False Steps, Failed Pathways, and Ultimately
Successful Route to the Bottom Half of Ivermectin," in Strategies
and Tactics in Organic Synthesis, Vol. 2, Ed. T. Lindberg, Academic
Press, New York, 1988, Chapter 7, pp 221-261. [pdf]
85. M. E. Jung and C. T. Vu,
"Intramolecular Diels-Alder Cycloadditions of Substituted Furfuryl E-2-(Phenylsulfonyl)acrylates,"
Tetrahedron Lett. 1988, 29, 6059-6062. [pdf]
86. M. E. Jung and K. T. Hogan,
"Chirality Transfer from Silicon to Carbon: Use of Optically Pure
Cyclic Silanes with a Binaphthalene Chiral Unit," Tetrahedron Lett.
1988, 29, 6199-6202. [pdf]
87. M. E. Jung, R. B. Blum, B. J.
Gaede, and M. R. Gisler, "Preparation and Diels-Alder Cycloadditions of
Substituted Vinylene Carbonates (1,3-Dioxol-2-ones) and Related
Compounds," Heterocycles 1989, 28, 93-97. [pdf]
88. M. E. Jung and S. M. Kaas,
"Facile Synthesis of a Substituted Bicyclo[4.2.1]nonane via an Anionic
[1,3]-Sigmatropic Shift: Use of Long Range 2D HETCOR and Difference NOE
in Structure Determination," Tetrahedron Lett. 1989, 30, 641-644. [pdf]
89. M. E. Jung, W. D. Vaccaro, and
K. R. Buszek, "Asymmetric Diels-Alder Reactions of Chiral Alkoxy
Iminium Salts," Tetrahedron Lett. 1989, 30, 1893-1896. [pdf]
90. M. E. Jung and J. Gervay,
"Solvent Effects in Intramolecular Diels-Alder Reactions of 2-Furfuryl
Methyl Fumarates: Evidence for a Polar Transition State," J. Am.
Chem. Soc. 1989, 111, 5469-5470. [pdf]
91. M. E. Jung, D. Jachiet, and J.
C. Rohloff, "Facile Chemical Synthesis of S,S-Isodityrosine,
A Naturally-Occurring Cross-Linking Amino Acid," Tetrahedron Lett.
1989, 30, 4211-4214. [pdf]
92. M. E. Jung and Y. H. Jung,
"Rapid Synthesis of
β-Hydroxy-α-amino
Acids, such as L-Threonine, β-Hydroxyphenylalanine,
and β-Hydroxyleucine,
via an Application of the Sharpless Asymmetric Epoxidation," Tetrahedron
Lett. 1989, 30, 6637-6640. [pdf]
93. M. E. Jung, I. D. Trifunovich,
J. M. Gardiner, and G. L. Clevenger, "Preparation of Modified
Nucleosides from Glucosamine: Rapid and Efficient Formal Total
Synthesis of Several 2'-Deoxy C-Nucleosides," J. Chem. Soc., Chem.
Commun. 1990, 84-85. [pdf]
94. M. E. Jung and W. Lew,
"Diastereoselective Organocuprate Addition to Homochiral Ketals of
3-Acetylcyclopent-2-en-1-one," Tetrahedron Lett. 1990, 31, 623-626. [pdf]
95. M. E. Jung, "Substituent and
Solvent Effects in Intramolecular Diels-Alder Reactions," Synlett
1990, 186-190. [pdf]
96. M. E. Jung and S J. Miller,
"Preparation of N-Alkadienyl N-E-2-Arylethenylcarbamates via
Sulfoxide Elimination in a Synthetic Approach to Lycorine," Heterocycles
1990, 30, 839-854. [pdf]
97. M. E. Jung and J. Gervay, "A
New NMR Technique for Measuring the Ground State Populations of Formate
Esters: Polar Aprotic Solvents Favor the s-cis (E)-Isomer of t-Butyl
Formate," Tetrahedron Lett. 1990, 31, 4685-4688. [pdf]
100. M. E. Jung and J. Gervay,
"Studies on the Gem-Dialkyl Effect in the Intramolecular Diels-Alder
Reaction of 2-Furfuryl Methyl Fumarates: the Reactive Rotamer Effect,
the Enthalpic Basis for the Acceleration, and Evidence For A Polar
Transition State," J. Am. Chem. Soc. 1991, 113,
224-232. [pdf]
102. M. E. Jung and J. M. Gardiner,
"Synthetic Approaches to 3'-Azido-3'-deoxythymidine and Other Modified
Nucleosides," J. Org. Chem. 1991, 56, 2614-2615. [pdf]
103. M. E. Jung and A. Hagiwara,
"New Alkene-forming Reaction: Phenanthrenes from
2-(2-Formylphenyl)benzaldehyde Bis-tosylhydrazone Decomposition," Tetrahedron
Lett. 1991, 32, 3025-3028. [pdf]
104. M. E. Jung, C. Castro, and J.
M. Gardiner, "Rapid Synthesis of 2',3'-Dideoxycytidine (ddC) from a
Simple Achiral Precursor," Tetrahedron Lett. 1991, 32,
5717-5720. [pdf]
105. M. E. Jung and C. N.
Zimmerman, "New Synthesis of Methyl 1,3-Butadiene-2-carboxylate by the
Cheletropic Extrusion of Carbon Monoxide from
3-Carbomethoxy-3,4-pentadienal and a Study of Its Dimerization To Give
Dimethyl Mikanecate (Dimethyl
4-Ethenyl-1-cyclohexene-1,4-dicarboxylate)," J. Am. Chem. Soc. 1991,
113, 7813-7814. [pdf]
106. M. E. Jung and G. L.
Clevenger, "Conversion of D-Mannose into
1,5-Anhydro-D-Allitol-4,6-acetonide; Unusual Intramolecular Epoxy
Alcohol Opening in Base," Tetrahedron Lett. 1991, 32, 6089-6092. [pdf]
107. M. E. Jung, "Stabilized
Nucleophiles with Electron Deficient Alkenes and Alkynes," Chapter 1.1,
in Volume 4 of "Comprehensive Organic Synthesis," Pergamon Press,
Oxford, 1991, pp 1-67. [pdf]
108. M. E. Jung and Y. M. Choi,
"New Synthesis of 2-Azetines and 1-Azabutadienes and the Use of the
Latter in Diels-Alder Reactions; Total Synthesis of (±) δ-Coniceine,"
J. Org. Chem.
1991, 56, 6729-6730. [pdf]
109. M. E. Jung and I. D.
Trifunovich, "Efficient Synthesis of 2',3'-Dideoxynucleosides and
2',3'-Dideoxy C-Nucleosides from D-Glucosamine," Tetrahedron Lett.
1992, 33, 2921-2924. [pdf]
110. M. E. Jung and J. M. Gardiner,
"Synthesis of Antiviral Nucleosides from Crotonaldehyde. Part 3. Total
Synthesis of Didehydrodideoxythymidine (d4T)," Tetrahedron Lett.
1992, 33, 3841-3844. [pdf]
111. M. E. Jung, L. Zeng, T. Peng,
H. Zeng, Y. Le, and J. Su, "Total Synthesis of Bao Gong Teng A, a
Natural Antiglaucoma Compound," J. Org. Chem. 1992, 57,
3528-3530. [pdf]
112. M. E. Jung, I. D. Trifunovich,
and N. Lensen, "Easy Preparation of a Cyclobutanone Ketal via a Radical
Cyclization. The Gem-Dialkoxy Effect," Tetrahedron Lett. 1992, 33, 6719-6722. [pdf]
113. M. E. Jung, D. C. D'Amico, and
W. Lew, "Efficient Total Synthesis of the Cytotoxic Halogenated
Monoterpene Aplysiapyranoid A," Tetrahedron Lett. 1993,
34, 923-926. [pdf]
114. M. E. Jung and C. Castro, "New
Approach to the Synthesis of β-2'-Deoxyribonucleosides:
Intramolecular Vorbrüggen
Coupling," J. Org. Chem. 1993, 58,
807-808. [pdf]
115. M. E. Jung and A. W. Sledeski,
"Efficient Total Synthesis of Racemic and Optically Active Cyclobut-A
and Simple Analogues," J. Chem. Soc., Chem. Commun. 1993,
589-591. [pdf]
116. M. E. Jung, I. D. Trifunovich,
and A. W. Sledeski, "A Simple Technique to Distinguish Between C
s
and C
2
Diastereomeric Diols Derived from
Chiral
Substrates," Heterocycles 1993, 35, 273-282. [pdf]
117. M. E. Jung and A. Vidal Gomez,
"Efficient Method for the Preparation of 2α,
3β
-Dichloro-4,4,10-trimethyldecalin Systems as a Route for the Synthesis
of Dichlorolissoclimide," Tetrahedron Lett. 1993, 34,
2891-2894. [pdf]
118. M. E. Jung and C. S. Siedem,
"Efficient Synthesis of a Hexasubstituted Aromatic Ring via an
Intramolecular Michael-Aldol Process: Preparation of a Late Tricyclic
Intermediate for the Synthesis of Pseudopterosin A," J. Am.
Chem.
Soc. 1993, 115,
3822-3823. [pdf]
119. M. E. Jung and H. Rhee, "New
Efficient Method for the Synthesis of the Antiviral Agent Carbovir," Tetrahedron
Lett. 1993, 34,
4449-4452. [pdf]
121. Y. Nagao, M. Takahashi, Y.
Abe,
T. Misono, and M. E. Jung, "Synthesis of 1,1-Dialkoxy Derivatives of
2,5-Diphenylsilacyclopent-3-ene and 2,5-Diphenylsilacyclopentane," Bull.
Chem. Soc. Jpn. 1993, 66, 2294-2296. [pdf]
123. M. E. Jung and D. C. D'Amico,
"Enantiospecific Synthesis of All Four Diastereomers of
2-Methyl-3-((trialkylsilyl)oxy)alkanals: Facile Preparation of Aldols
by Non-Aldol Chemistry," J. Am. Chem. Soc. 1993, 115,
12208-12209. [pdf]
145. Y. Nagao, N. Namiki, S. Sakamoto,
and M. E. Jung, "Synthesis of
2,5-Dimethyl and 2,5-Diphenylsilacyclopentane Derivatives and Their
Reactions," in "43rd Symposium on Organometallic Chemistry,"
Kinki Chemical Society, Osaka, Japan, 1996, Abstract PA 112, pp. 50-51. [pdf]
233. M. E. Jung, N. Nishimura, and A. R. Novack, "Versatile Diastereoselectivity in Formal
[3,3]-Sigmatropic Shifts of Substituted
1-Alkenyl-3-alkylidenecyclobutanols and Their Silyl Ethers," J.
Am. Chem. Soc. 2005, 127, 11206-11207.[pdf]
234. Y. Akiba, M. E. Jung, S. Ouk, and J. D. Kaunitz, "A Novel Small Molecule CFTR Inhibitor Attenuates
HCO3
Secretion And Duodenal Ulcer
Formation In
Rats" Amer.
J. Physiol. GI Liver Physiol. 2005
, 289, G753-G759.[pdf]
235. J. A. Richardson, C. M. Amantea, K. Nguyen, M. E. Jung, T. J. Hahn, and
F. Parhami, "Characterization of Osteogenic Oxysterols and their
Molecular Mechanism(s) of Action," J. Bone Mineral Res.
2005, 20, Abstract M427, S414-S415. [pdf]
240. M. T. Naik, N. Suree, N. U. Ilangovan, C. K. Liew, J. Clemens, M. E. Jung, and R. T. Clubb, "A
Calcium Modulated Loop Closure Mechanism Activates Cell Surface Protein
Anchoring by the Staphylococcus aureus Sortase A Transpeptidase,"
J. Biol. Chem. 2006, 281, 1817-182642. [pdf]
241. Y.-L. Zhao, C. P. Suhrada, M. E. Jung and K. N. Houk, "The
3-Vinylmethylenecyclobutane–4-Methylenecyclohexene Rearrangement:
Theoretical Investigation of a Stereoselective Stepwise Cope
Rearrangement," J. Am. Chem. Soc. 2006, 128,
11106-11113. [pdf]
242. M. E. Jung and B. A. Duclos, "Synthetic Approach to Analogues of Betulinic Acid," Tetrahedron
2006, 62, 9321-9334. [pdf]
245. M. E. Jung and M. Murakami, "Total Synthesis of (±)-Hedychilactone
B: Stepwise Allenoate Diene Cycloaddition to Prepare Trimethyldecalin
Systems," Org. Lett. 2007, 9, 461-463. [pdf]
256. M. E. Jung and D. A. Allen, "Facile
Synthesis of syn
2-Alkyl-3-trialkylsilyloxycycloalkanones via the First Non-Aldol Aldol
Process of 2,3-Epoxycycloalkanols," Org. Lett. 2008, 10,
2039-2041. [pdf]
98. M. E. Jung, Y. H. Jung, and Y.
Miyazawa, "Facile Synthesis of Both Enantiomers of 2, 3, 4, 5,
6-Pentafluoro-α-methoxybenzeneacetic Acid in High Optical
Purity," Tetrahedron Lett. 1990, 31, 6983-6986. [pdf]
99. M. E. Jung and D. B. Head,
"Synthesis of Fully Functionalized Intermediates for the Bottom Half of
the 4-Acyloxymethyl Milbemycin Antibiotics," Bull. Soc.
Chim. Fr. 1990, 830-834.
[pdf]
101. M. E. Jung and W. Lew,
"Efficient Total Synthesis of the Cytotoxic Halogenated Monoterpene
Aplysiapyranoid D," J. Org. Chem. 1991, 56,
1347-1349. [pdf]
120. M. E. Jung, C. N. Zimmerman, G. T. Lowen, and S. I. Khan,
"Diastereocontrol in Intermolecular
Diels-Alder Reactions of Allenic Lactones: Synthetic Approach to the
Plaunols," Tetrahedron Lett. 1993, 34,
4453-4456. [pdf]
122. M. E. Jung and S. W. T. Choe,
"Stereospecific Intramolecular Formyl Transfer via Radical
Cyclization-Fragmentation: Preparation of Alkyl 2-Deoxy-2α-formylglycopyranosides and Similar
Compounds," Tetrahedron Lett. 1993, 34,
6247-6250. [pdf]
124. M. E. Jung and H. L. Rayle, "An
Improved Synthesis of 4-Methylene-2-cyclohexen-1-one," Synth.
Commun. 1994, 24, 197-199. [pdf]
125. M. E. Jung, C. H. Kim, and L. v.
d. Bussche, "Vicarious Nucleophilic Aromatic Substitution via Trapping
of an
α-Ketosulfonium Ion Generated by a
Pummerer-Type Rearrangement of 2-(Phenylsulfinyl)phenols: Preparation
of Biaryls," J. Org. Chem. 1994, 59,
3248-3249. [pdf]
126. P. M. Harrington and M. E. Jung,
"Stereoselective Bromination of a β-Ribofuranosyl
Amide.
Enantioselective Synthesis of (+)-Hydantocidin," Tetrahedron Lett.
1994, 35, 5145-5148. [pdf]
127. M. E. Jung and H. Rhee, "π
-Allylpalladium Formation from Allylic Amines via N,N-Ditosylimides and
N-Tosylamides: Efficient Synthesis of the Antiviral Agent Carbovir," J.
Org. Chem. 1994, 59, 4719-4720. [pdf]
128. M. E. Jung and J. M. Gardiner,
"Asymmetric Synthesis of
Carbohydrates: Synthesis of 2-Deoxy-D- and 2-Deoxy-L-xylofuranosides
from a
Simple Achiral Precursor," Tetrahedron Lett. 1994, 35, 6755-6758. [pdf]
129. M. E. Jung and S. M. Dansereau,
"Benzo[H]-1,6-naphthyridine
Synthesis via Intramolecular
Diels-Alder Reactions of Aryl Oxazoles: Synthetic Approach to
2-Bromoleptoclinidinone," Heterocycles 1994, 39, 767-778. [pdf]
130. M. E. Jung, D. Jachiet, S. I.
Khan, and C. Kim, "New Method for the
Preparation of o-Aryloxyphenols:
Pummerer-Type Rearrangement of an o-Hydroxyaryl
Sulfoxide," Tetrahedron Lett.
1995, 36, 361-364. [pdf]
131. M. E. Jung and S. W. T. Choe,
"Total Synthesis of Cyclophellitol and
(1R,2S)-Cyclophellitol from D-Mannose," J.
Org.
Chem. 1995, 60, 3280-3281. [pdf]
132. M. E. Jung and Y. H. Jung,
"Efficient Enantioselective Synthesis of
(2R,3S) Methyl β-Hydroxytyrosinate
from Achiral Starting Materials," Synlett 1995, 563-564. [pdf]
133. M. E. Jung and D. C. D'Amico,
"Stereospecific Rearrangement of
Optically Active Tertiary Allylic Epoxides to Give Optically Active
Quaternary
Aldehydes: Synthesis of α-Alkyl Amino Aldehydes
and Acids," J. Am. Chem. Soc.
1995, 117, 7379-7380. [pdf]
134. M. E. Jung and M. Kiankarimi,
"Gem-Dialkoxy Effect in Radical
Cyclizations to Produce Cyclopropane Derivatives: Unusual Oxidation of
a
Dialkoxyalkyl Radical," J. Org. Chem. 1995, 60, 7013-7014. [pdf]
135. M. E. Jung and L. S. Starkey,
"New Preparation of o-Aryloxyphenols via Cyclohexenone Oxides," Tetrahedron
Lett. 1995, 36,
7363-7366. [pdf]
136. E. D. Murray, Jr., D. Kantoci, S.
A. DeWind, A. E. Bigornia, D. C.
D'Amico, J. G. King, Jr., T. Pham, B. H. Levine, M. E. Jung, and W. J.
Wechter,
"Endogenous Natriuretic Factors 3: Isolation and Characterization of
Human
Natriuretic Factors LLU-α, LLU-β1, and LLU-γ,"
Life Sci. 1995, 57,
2145-2161. [pdf]
137. M. E. Jung, Y.-M. Cho, and Y. H.
Jung, "Facile Synthesis of Optically
Active 2-Hydroxymethyl-4-methylenecyclohexanol. Total De Novo Synthesis
of
Carbocyclic Sugars," Tetrahedron Lett. 1996, 37, 3-6. [pdf]
138. M. E. Jung and T. Lazarova,
"Preparation of (Phenylsulfinyl)phenols
from Aryl Sulfinates: 'Thia-Fries Rearrangement'," Tetrahedron
Lett. 1996, 37, 7-8. [pdf]
139. M. E. Jung and B. T. Vu,
"Substituent Effects on Intramolecular
Dipolar Cycloadditions: The Gem-Dicarboalkoxy Effect," Tetrahedron
Lett. 1996, 37,
451-454. [pdf]
140. D. P. C. McGee, D. P. Sebesta, S.
S. O'Rourke, R. L. Martinez, M. E. Jung,
and W. A. Pieken, "Novel Nucleosides via Intramolecular
Functionalization
of 2,2'-Anhydrouridine Derivatives," Tetrahedron Lett. 1996, 37, 1995-1998. [pdf]
141. W. J. Wechter, D. Kantoci, E. D.
Murray, Jr., D. C. D'Amico, M. E. Jung,
and W.-H. Wang, "A New Endogenous Natriuretic Factors: LLU-α," Proc. Natl. Acad. Sci. U. S.
A. 1996, 93, 6002-6007. [pdf]
142. M. E. Jung and B. T. Vu,
"Complete Diastereocontrol in Intramolecular
1,3-Dipolar Cycloadditions of 2-Substituted 5-Hexenyl and 5-Heptenyl
Nitrones:
Application to the Synthesis of the β-Lactam
Antibiotic 1β-Methylthienamycin," J. Org.
Chem. 1996, 61, 4427-4433. [pdf]
143. M. E. Jung and C. J. Nichols,
"Highly Stereoselective Synthesis of
trans, trans-4-Aryl-2,3-oxetanedimerthanols: Preparation of Oxetanocin
A
Analogues," Tetrahedron Lett.
1996, 37, 7667-7670. [pdf]
144. W. J. Wechter, E. D. Murray, Jr., D. Kantoci, and M. E.
Jung, "Characterization of two New Endogenous Natriuretic Factors," J. Am. Soc. Nephrology 1996, 7, A2867. [pdf]
146. M. E. Jung and C. J.
Nichols, "A Novel Tandem
[1,2]-Brook/Retro-[1,6]-Brook Rearrangement of a
1-Trimethylsilyl-2,4-pentadien-1-ol Anion," J. Org. Chem. 1996, 61, 9065-9067. [pdf]
147. C. Giessner-Prettre, S. Hückel,
J. Maddaluno, and M. E. Jung, "Molecular
Mechanics/ Continuum Reaction Field/Quantum Mechanics Study of the
Intramolecular Diels-Alder Reaction of 2-Furfuryl Derivatives," J.
Org.
Chem. 1997, 62, 1439-1448. [pdf]
148. M. E. Jung and T. I. Lazarova,
"Efficient Synthesis of Selectively
Protected L-Dopa Derivatives from L-Tyrosine via Reimer-Tiemann and
Dakin
Reactions," J. Org. Chem. 1997, 62, 1553-1555. [pdf]
149. Y. Nagao, K. Miyakawa, S.
Sakamoto, M. Takahashi, Y. Abe, and M. E. Jung,
"Synthesis of trans-1,1-dialkoxy-2,5-diphenyl-1-sila-3-cyclopentenes
and
their 2-alkyl derivatives," Nippon Kagaku Kaishi 1997, 213-218. [pdf]
150. M. E. Jung and K. L. Anderson,
"Stereospecific Rearrangements of
Optically Active 2-Aryl-3-Ethenyloxiranes to Give Optically Active β-Ethenylbenzeneethanols: Benzyl vs. Allyl
Cations and
an Efficient Synthesis of (S)-Ibuprofen,"
Tetrahedron Lett. 1997, 38, 2605-2608. [pdf]
151. M. E. Jung and Y. Xu, "Efficient
Syntheses of L-Ribose and 2-Deoxy
L-Ribose from D-Ribose and L-Arabinose," Tetrahedron Lett. 1997, 38, 4199-4202. [pdf]
152. M. E. Jung and L. S. Starkey,
"Total Synthesis of
S,S-Isodityrosine," Tetrahedron
1997, 53, 8815-8824. [pdf]
153. M. E. Jung and H. L. Rayle,
"Generation of [5.5.n]Tricyclic Ring
Systems by Radical Promoted Inter- and Intramolecular [3 + 2]
Cycloadditions," J. Org. Chem.
1997, 62, 4601-4609. [pdf]
154. M. E. Jung and R. Marquez,
"Gem-Disubstituent Effects in Small Ring
Formation: Novel Ketal Ring Size Effect," Tetrahedron Lett. 1997, 38, 6521-6524. [pdf]
155. M. E. Jung and M. H. Parker,
"Synthesis of Several Naturally
Occurring Polyhalogenated Monoterpenes of the Halomon Class," J.
Org.
Chem. 1997, 62, 7094-7095. [pdf]
156. M. E. Jung and D. C. D'Amico,
"Stereospecific Formation of Optically
Active 2-([Trialkylsilyloxy]methyl)tetrahydrofuran-3-ols via
Diastereoselective Epoxidation and Rearrangement of
5-[(Trialkylsilyl)oxy]-2-alken-1-ols," J. Am. Chem. Soc. 1997, 119, 12150-12158. [pdf]
157. M. E. Jung and T. W. Johnson,
"Total Synthesis of
7-Deoxyxestobergsterol A, a Novel Pentacyclic Steroid of the
Xestobergsterol
Class," J. Am. Chem. Soc. 1997, 119, 12412-12413. [pdf]
158. M. E. Jung and S. Angelica, "An
Intramolecular Prins Double
Cyclization Catalyzed By Silyl Triflates," J. Org. Chem. 1997, 62, 9182-9187. [pdf]
159. M. E. Jung and C. J. Nichols,
"Synthesis of Methylene-Expanded
Oxetanocin Isonucleosides in Both Enantiomeric Forms," J.
Org. Chem. 1998, 63, 347-355. [pdf]
160. M. E. Jung and Y. Xu, "Efficient
Synthesis of Specifically Deuterated
Nucleosides: Preparation of 4'-Deuteriothymidine," Heterocycles 1998, 47, 349-356. [pdf]
161. M. E. Jung and M. Kiankarimi,
"Substituent and Solvent Effects in the
Intramolecular Diels-Alder Reaction of 6-Furyl Hexenoates," J.
Org.
Chem. 1998, 63, 2968-2974. [pdf]
162. M. E. Jung and O. Kretschik,
"Enantiospecific Total Synthesis of
L-2',3'-Dideoxy Isonucleosides via Regioselective Opening of Optically
Active
C2-Symmetric 1,4-Pentadiene bis-Epoxide," J. Org. Chem. 1998, 63, 2975-2981. [pdf]
163. M. E. Jung and B. T. Fahr, "Total
Synthesis of the Cytotoxic Marine
Natural Product, Aplysiapyranoid C," J. Org. Chem. 1998, 63, 2982-2987. [pdf]
164. M. E. Jung and C. J. Nichols, "A
de novo Synthesis of Ethyl
2-Deoxy-L-ribosides," Tetrahedron Lett. 1998, 39, 4615-4618. [pdf]
165. M. E. Jung, C. Castro, and S. I.
Khan, "Novel Lewis Acid-Catalyzed
Rearrangement of a Sugar-Base Hybrid to Afford an Anhydronucleoside," Nucleosides
Nucleotides 1998, 17, 2383-2387. [pdf]
166. M. E. Jung and M. Kiankarimi,
"Synthesis of Methylene-Expanded
2',3'-Dideoxyribonucleosides," J. Org. Chem. 1998, 63, 8133-8144. [pdf]
167. M. E. Jung, U. Karama, and R.
Marquez, "Conversion of Homoallylic
Alcohols with Alkene Protection to the Corresponding Methyl Ketones," J.
Org. Chem. 1999, 64, 663-665. [pdf]
168. M. E. Jung, R. Marquez, and K. N.
Houk, "Prediction of Variations in
Efficiencies of 4-Exo Trig Radical Cyclizations," Tetrahedron
Lett. 1999, 40, 2661-2664. [pdf]
169. M. E. Jung and R. Marquez,
"Rearrangement of Epoxides in Non-aldol
Aldol Process: Allylic vs. Tertiary and Secondary Carbocationic
Centers," Tetrahedron
Lett. 1999, 40, 3129-3132. [pdf]
170. M. E. Jung and N. Nishimura,
"Stereoselective Formation of Formal Exo
Diels-Alder Adducts of Silyloxydienes and Allenecarboxylates," J.
Am.
Chem. Soc. 1999, 121, 3529-3530. [pdf]
171. M. E. Jung and T. I. Lazarova,
"New Efficient Method for the Total
Synthesis of (S,S)-Isodityrosine from Natural Amino Acids," J.
Org. Chem. 1999, 64, 2976-2977. [pdf]
172. M. E. Jung, "New Gem- and
Vic-Disubstituent Effects on
Cyclizations," Synlett 1999, 843-846. [pdf]
173. M. E. Jung, C. J. Nichols, O.
Kretschik, and Y. Xu, "Synthesis and
Testing of New Modified Nucleosides," Nucleosides Nucleotides 1999, 19, 541-6. [pdf]
174. M. E. Jung, W. S. Lee, and D.
Sun, "Extension of Non-aldol Aldol
Process to Bis(propionates): Synthesis of Four Diastereomeric
3,5-Dialkoxy-2,4-dimethylalkanals,"Org. Lett. 1999, 1, 307-309. [pdf]
175. M. E. Jung and J. Pontillo,
"Facile Preparation of Allenic
Hydroxyketones via Rearrangement of Propargylic Alcohols," Org.
Lett. 1999, 1, 367-369. [pdf]
176. A. D. Watson, G. Subbanagounder,
D. S. Welsbie, K. F. Faull, M. Navab, M.
E. Jung, A. M. Fogelman, and J. A. Berliner, "Structural Identification
of
a Novel Pro-inflammatory Epoxy Isoprostane Phospholipid in Mildly
Oxidized Low
Density Lipoprotein," J. Biol. Chem.
1999, 274, 24787-24798. [pdf]
177. M. E. Jung and J. M. MacDougall,
"First Enantioselective Total Synthesis
of the Endogenous Natriuretic Agent LLU-α,"
Tetrahedron Lett.
1999, 40, 6339-6342. [pdf]
178. M. E. Jung, W. Mengel, and T. L.
Newton, "A Short, Convenient
Synthesis of 2-Aryl-3,3-disubstituted Glycidic Esters via
Organometallic
Addition to α-Bromopyruvates," Synth. Commun. 1999, 29, 3659-3666. [pdf]
179. M. E. Jung, E. C. Yang, B. T. Vu,
M. Kiankarimi, E. Spyrou, and J.
Kaunitz, "Glycosylation of Fluoroquinolones Through Direct and
Oxygenated
Polymethylene Linkages as a Sugar-Mediated Active Transport System for
Antimicrobials,"
J. Med. Chem. 1999, 42, 3899-3909. [pdf]
180. M. E. Jung and T. W. Johnson,
"Unusual Cyclization Products Derived
from Photolysis of Breslow's Steroidal Benzophenone Esters," J.
Org.
Chem. 1999, 64, 7651-7653. [pdf]
181. M. E. Jung and U. Karama, "Highly
Diastereoselective Markovnikov
Hydration of 3,4-Dialkoxy-1-alkenes and 4,5-Dialkoxy-2-alkenes via a
Hydroboration-Oxidation Process," Tetrahedron Lett. 1999, 40, 7907-7910. [pdf]
182. M. E. Jung and Y. Xu, "Efficient
Synthesis of 2-Deoxy L-Ribose from
L-Arabinose: Mechanistic Information on the 1,2-Acyloxy Shift in Alkyl
Radicals," Org. Lett. 1999, 1, 1517-1519. [pdf]
183. M. E. Jung and T. W. Johnson,
"First Total Synthesis of
Xestobergsterol A and Active Structural Analogues of the
Xestobergsterols," Org. Lett.
1999, 1, 1671-1674. [pdf]
184. M. E. Jung and D. Sun,
"Stereoselective Production of β-Amino Alcohols and β-Thioacyl
Alcohols via an Application of the non-Aldol Aldol Process," Tetrahedron
Lett. 1999, 40, 8343-8346. [pdf]
185. C. Castro, C. Chen, and M. E.
Jung, "Intramolecular Glycosylation to
form 2,6-Dioxo-4-methoxypyrimidine Nucleosides via
O6,5'-Cyclonucleosides," Nucleosides Nucleotides 1999, 18, 2415-2423. [pdf]
186. H. Rhee, D.-O. Yoon, and M. E.
Jung, "Efficient Synthesis of the
Carbocyclic Nucleoside, (±)-Homocarbovir via Allylpalladium
Complex Formation from an Allyl N,N-Ditosylimide Substrate," Nucleosides
Nucleotides 2000, 19, 619-628. [pdf]
187. A. S. Fraser, A. M. Kawasaki, M.
E. Jung, and M. Manoharan, "An
Efficient Method for the Synthesis of 2'-O-Modified Nucleosides Via
Double
Alkylation using Cyclic Sulfates," Tetrahedron Lett. 2000, 41, 1523-1526. [pdf]
188. M. E. Jung and B. T. Fahr, "Novel
Base-Induced [1,2]-Acyl Shift of
Allylic Esters of Cyclopropane Carboxylic Acids," J. Org.
Chem. 2000, 65, 2239-2242. [pdf]
189. M. E. Jung and A. Toyota,
"Efficient Synthesis of Several
Methylene-Expanded Oxetanocin Nucleoside Analogues," Tetrahedron
Lett. 2000, 41, 3577-3581. [pdf]
190. M. E. Jung and R. Marquez,
"Efficient Synthesis of the C1-C11
Fragment of the Tedanolides. The Non-aldol Aldol Process in Synthesis,"
Org.
Lett. 2000, 2, 1669-1672. [pdf]
191. M. E. Jung, A. Huang, and T. W. Johnson, "Unusual
Diastereoselectivity in Intramolecular Diels-Alder Reactions of
Substituted
3,5-Hexadienyl Acrylates. Preference for a Boat-like Structure of the
Six-Atom
Tether due to Ester Overlap," Org. Lett. 2000, 2, 1835-1837. [pdf]
192. M. E. Jung and A. Huang, "Use of
Optically Active Cyclic N,N-Dialkyl Aminals in Asymmetric Induction,
" Org. Lett. 2000, 2, 2659-2661. [pdf]
193. Y. Nagao, S. Sakamoto, K.
Miyakawa, Y. Abe, and M. E. Jung, "Synthesis
of 1-substituted derivatives of 2,5-diphenylsilacyclopent-3-enes and
2,5-diphenylsila-cyclopentanes," Nippon Kagaku Kaishi 2000, 411-417. [pdf]
194. S. W. T. Choe and M. E. Jung,
"Preparation of Various C-2 Branched
Carbohydrates Using Stereospecific Intramolecular Radical Reactions," Carbohydr.
Res. 2000, 329, 731-744. [pdf]
195. M. E. Jung and C. P. Lee, "Use of
the Non-Aldol Aldol Process in the
Synthesis of the C1-C11 Fragment of the Tedanolides: Use of Lactol
Ethers in
Place of Tetrahydrofurans," Tetrahedron Lett. 2000, 41, 9719-9723. [pdf]
196. M. E. Jung and B. S. Lee,
"Unusual α-Methylation
of Alkoxyaryl Ketones with Higher Order Methyl Cuprate and Lithium
Bromide," J. Org. Chem. 2000, 65, 9241-9244. [pdf]
197. M. E. Jung and C. P. Lee,
"Synthesis of a Fully Functionalized Protected
C1-C11 Fragment for the Synthesis of the Tedanolides," Org.
Lett. 2001, 3, 333-336. [pdf]
198. M. E. Jung and T. W. Johnson,
"First Total Synthesis of
Xestobergsterol A and Active Structural Analogues of the
Xestobergsterols," Tetrahedron
2001, 57, 1449-1481. [pdf]
199. H. Cai, J. Strouse, D. Dumlao, M.
E. Jung, and S. Clarke, "Distinct
Reactions Catalyzed by Bacterial and Yeast trans-Aconitate
Methyltransferases," Biochemistry
2001, 40, 2210-2219. [pdf]
200. M. E. Jung and P. Davidov, "First
Conclusive Evidence of the Trapping
of Primary Ozonides," Org. Lett.
2001, 3, 627-629. [pdf]
201. D. J. Tantillo, K. N. Houk, and M. E. Jung, "Origins of
Stereoselectivity in Intramolecular Diels-Alder Cycloadditions of
Dienes and
Dienophiles Linked by Ester and Amide Tethers," J. Org. Chem. 2001, 66, 1938-1940. [pdf]
202. M. E. Jung and A. Toyota, "Preparation of 4'-Substituted Nucleosides
by Substitution of the Nucleoside 5'-Esters," J. Org. Chem. 2001, 66, 2624-2635. [pdf]
203. M. E. Jung and N. Nishimura, "Enantioselective Formal Total Synthesis
of (-)-Dysidiolide," Org. Lett.
2001, 3, 2113-2115. [pdf]
204. M. E. Jung and F. Slowinski, "Rhodium-Catalyzed Decomposition of
Indole-Substituted α-Diazo-β-Keto Esters: Three Different Reactions
Based on
Indole Oxidation State," Tetrahedron Lett. 2001, 42, 6835-6838. [pdf]
205. M. E. Jung and P. Davidov, "The First Reported Anionic Retro-Ene
Reaction," Org. Lett. 2001, 3, 3025-3027. [pdf]
206. M. E. Jung, A. Toyota, E. De Clercq, and J. Balzarini, "Synthesis and
Biological Activity of a Series of Methylene-Expanded Oxetanocin
Nucleoside Analogues," Monatshefte Chem.
2002, 133, 499-520. [pdf]
207. M. E. Jung and G. Piizzi, "Novel Rearrangements of
4-Silyl-3-buten-2-ones,"J. Org. Chem. 2002, 67, 3911-3914. [pdf]
208. M. E. Jung and J. Pontillo,
"Synthetic Approach to Analogues of the
Original Structure of Sclerophytin A," J. Org. Chem. 2002, 67, 6848-6851. [pdf]
209. M. E. Jung and P. D. Davidov,
"Efficient Synthesis of a Tricyclic BCD
Analogue of Ouabain: Lewis Acid Catalyzed Diels-Alder Reactions of
Sterically
Hindered Systems," Angew. Chem. Int. Ed.
2002, 41, 4125-4128. [pdf]
210. M. E. Jung and A. van den Heuvel,
"Diastereoselectivity in non-Aldol
Aldol Reactions: Silyl Triflate Promoted Payne Rearrangements," Tetrahedron
Lett. 2002, 43, 8169-8172. [pdf]
211. M. E. Jung, A. Kers, G. Subbanagounder, and J. A. Berliner,
"Endothelial Activation by an Epoxy Isoprostane Phsopholipid. Total
Synthesis of Epoxy Isoprostanes," Chem Commun. 2003, 196-197. [pdf]
212. M. E. Jung and G. Piizzi, "Synthesis of the A/B Ring System of
Ouabain," Org. Lett. 2003 5, 137-140. [pdf]
213. A. G. Leach, R. Wang, G. E. Wohlhieter, S. I. Khan, M. E. Jung, and K. N.
Houk, "Theoretical Elucidation of Kinetic and Thermodynamic Control of
Radical Addition Regioselectivity," J. Am. Chem. Soc. 2003, 125, 4271-4278. [pdf]
214. M. E. Jung and G. Piizzi, "Synthetic Approach to the AB Ring System
of Ouabain," J. Org. Chem. 2003, 68,
2572-2582. [pdf]
215. M. E. Jung and J. Pontillo, "Synthetic Approach to Analogues of
Sclerophytin A," Tetrahedron 2003, 59, 2729-2736. [pdf]
216. M. E. Jung, B. Hoffmann, B. Rausch, and J.-M. Contreras, “Use of Hindered
Silyl Ethers as Protecting Groups for the Non-Aldol Aldol Process,” Org.
Lett. 2003, 5, 3159-3161. [pdf]
217. K. M. Connolly, B. M. Smith, R. Pilpa, U. Ilangovan, M. E. Jung, and R. T.
Clubb, “Sortase from S. aureus
Does not Contain a Thiolate-imidazolium Ion Pair in its Active Site,” J.
Biol. Chem. 2003, 278,
34061-34065. [pdf]
218. M. E. Jung, A. van den Heuvel, A. G. Leach, and K. N. Houk, “Unexpected
Syn Hydride Migration in the Non-aldol Aldol Reaction,”Org.
Lett. 2003, 5, 3375-3378. [pdf]
219. M. E. Jung and J. I. Wasserman, “Efficient Synthesis of Vinyl Chlorides
and/or gem-Dichlorides
from Ketones by Treatment with Tungsten Hexachloride,” Tetrahedron
Lett. 2003, 44, 7273-7275. [pdf]
220. M. E. Jung and A. van den Heuvel, "Tandem non-Aldol Aldol-Mukaiyama
Aldol Process: Synthesis of Bis-(β-Silyloxy)ketones,"
Org. Lett 2003, 5, 4705-4707. [pdf]
221. M. E. Jung and B. A. Duclos, "Diastereoselectivity in the Carroll
Rearrangement of β-Keto Esters of Tertiary Allylic Alcohols,"
Tetrahedron
Lett.
2004, 45, 107-109. [pdf]
222. J. E. Katz, D. S. Dumlao, J. I. Wasserman, M. G. Lansdown, M. E. Jung, K. F. Faull and S. Clarke,
"3-Isopropylmalate is the Major Endogenous Substrate of the
Saccharomyces cerevisiae trans-Aconitate Methyltransferase,"
Biochemistry
2004, 43, 5976-5986. [pdf]
223. M. E. Jung and A. Maderna, "Allylation of Acetals and Ketals with Allyltrimethylsilane Catalyzed
by the Mixed Lewis Acid System AlBr3
/CuBr," Tetrahedron
Lett.
2004, 45, 5301-5304. [pdf]
224. C. K. Liew, B. T. Smith, R. Pilpa, U. Ilangovan, K. M. Connolly, M. E. Jung, and R. T. Clubb,
"Localization and mutagenesis of the sorting signal binding site on
sortase A from Staphylococcus aureus,"FEBS Lett. 2004, 571, 221-226. [pdf]
225. M. E. Jung and S.-J. Min, "Novel Formation of a Bridged Bicyclic Furan by Rearrangement of a
Tetrahydroxydecalinone," Tetrahedron Lett.
2004, 45, 6753-6755. [pdf]
226. M. E. Jung and A. Maderna, "Microwave-assisted Allylation of Acetals with Allyltrimethylsilane in
the Presence of CuBr," J. Org. Chem.
2004 69, 7755-7757. [pdf]
227. Y. Nagao, C. Kimura, K. Kozawa, and M. E. Jung,"Synthesis, Stereochemistry, and Reactions of
2,5-Diphenylsilacyclopentenes," Silicon Chem. 2003,
2, 99-107. [pdf]
228. M. E. Jung, S.-J. Min, K. N. Houk, and D. Ess, "Synthesis and Relative Stability of 3,5-Diacyl
4,5-Dihydro-1H-Pyrazoles Prepared by Dipolar Cycloaddition of Enones
and
α
-Diazoketones," J. Org.
Chem.
2004, 69,
9085-9089. [pdf]
229. M. E. Jung, D. Ho, and H. V. Chu, "Synthesis of Highly Substituted Cyclohexenes via Mixed Lewis
Acid-Catalyzed Diels-Alder Reactions of Highly Substituted Dienes and
Dienophiles," Org. Lett. 2005, 7, 1645-1651. [pdf]
230. M. E. Jung and G. Piizzi, "Gem-Disubstituent Effect: Theoretical Basis and Synthetic
Applications," Chem. Rev.
2005, 105,
1735-1766. [pdf]
231. M. E. Jung and A. Maderna, "Synthesis of Bicyclo[2.2.2]oct-5-en-2-ones via a Tandem Intermolecular
Michael Addition Intramolecular Aldol Process (a Bridged Robinson
Annulation)," Tetrahedron Lett.
2005, 46, 5057-5061.[pdf]
232. M. E. Jung and S.-J. Min, "Intramolecular Diels-Alder Reactions of Optically Active Allenic
Ketones: Chirality Transfer in the Preparation of Substituted
Oxa-bridged Octalones," J. Am. Chem. Soc. 2005, 127
236. M. E. Jung, J. A. Berliner, D. Angst, D. Yue, L. Koroniak, A. D. Watson, and R. Li, "Total Synthesis
of the Epoxy Isoprostane Phospholipids PEIPC and PECPC," Org. Lett. 2005, 7, 3933-3935.
[pdf]
237. M. E. Jung and A. R. Novack, "Formation of 3,4-Dimethyl-2-pyrones from Allene Carboxylates and
2-Silyloxydienes via 3-Carboethoxyethylidene Cyclobutanols" Tetrahedron
Lett.
2005, 46, 8237-8240.[pdf]
238. M. E. Jung, J. J. Clemens, N. Suttee, C. K. Liew, and R. T. Clubb, "Synthesis of (2R,
3S) 3-Amino-4-mercapto-2-butanol, a Threonine Analogue for
Covalent Inhibition of Sortases,"
Bioorg. Med. Chem. Letts. 2005, 15, 5076-5079. [pdf]
239. M. E. Jung and W.-J. Kim, "Practical Syntheses of Dyes for Difference Gel Electrophoresis
(DIGE)," Bioorg. Med. Chem. 2006, 14
243. M. E. Jung and M. Murakami, "Total Synthesis of (±)-Hedychenone: Trimethyldecalin
Terpenes via Stepwise Allenoate Diene Cycloaddition," Org.
Lett. 2006, 8, 5857-59. [pdf]
244. M. E. Jung and D. G. Ho, "Stepwise Acid-Promoted Double-Michael Process: an Alternative to
Diels-Alder Cycloadditions for Hindered Silyloxydiene-Dienophile
Pairs," Org. Lett. 2007, 9,
375-378. [pdf]
246. M. E. Jung and S.-J. Min, "Approaches to the Synthesis of
Arisugacin A," Tetrahedron 2007, 63, 3682-3701. [pdf]
247. M. C. Duncan, D. G. Ho, J. Huang, M. E. Jung, and G. S. Payne,
"Composite Synthetic Lethal Identification of Membrane Traffic
Inhibitors," Proc. Natl. Acad. Sci. U. S. A. 2007, 104,
6235-6240. [pdf]
248. J. M. Tsay, M. Trzoss, L. Shi, X. Kong, M. Selke, M. E. Jung, and
S. Weiss, "Singlet Oxygen Production by Peptide-Coated
Quantum Dot-Photosensitizer Conjugates," J. Am. Chem. Soc. 2007,
129, 36865-6871. [pdf]
249. N. Suree, M. E. Jung, and R. T. Clubb, "Recent Advances Towards
New Anti-infective Agents that Inhibit Cell Surface Protein Anchoring
in Staphylococcus aureus and Other Gram-positive Pathogens," Mini
Reviews in Medicinal Chemistry 2007, 7,
991-1000. [pdf]
250. M. E. Jung and D. Yoo, "Synthesis of the C1
-C12
Fragment of the Tedanolides.
Aldol-Non-Aldol Aldol Approach," Org.
Lett. 2007, 9, 3543-3546. [pdf]
251. M. E. Jung and D. Yoo, "Unprecedented Rearrangement of a
4-Alkoxy-5-bromoalk-2-en-1-ol to a Cyclopentenone via an Iso-Nazarov
Cyclization Process," J. Org. Chem. 2007, 72,
8565-8568. [pdf]
252. M. E. Jung and J. M. Murphy, "Functional Group Selectivity in Reactions
of Epoxides with Tungsten Hexachloride," Tetrahedron Lett. 2007,
48, 8388-8391.[pdf]
253. M. E. Jung and T.-H. Zhang, "New Protocol for Anti-Selective Aldol
Condensation of Ethyl Ketones with
α-Alkoxyaldehydes," Org. Lett. 2008,
10, 1371-40. [pdf]
254. M. E. Jung and D. Yoo, "Synthesis of the C1
-C12
Fragment of the Tedanolides. Selective
Hydroboration-protonation of
Allylic Alcohol Approach," Tetrahedron
Lett. 2008, 49, 816-819. [pdf]
255. W. Zhang, K. Watanabe, X. Cai, M. E.
Jung, Y. Tang, and J. Zhan,
"Identifying the Minimal Enzymes Required for Anhydrotetracycline
Biosynthesis," J. Am. Chem. Soc. 2008, 130,
6068-6069. [pdf]
257. M. E. Jung and G-Y. Im, "Convergent
Total Synthesis of the Racemic HIF-1 Inhibitor Laurenditerpenol," Tetrahedron
Lett. 2008, 49,
4962-4964. [pdf]
258. M. E. Jung and H. V. Chu, "Preparation
of a Functionalized Tetracyclic Intermediate for the Synthesis of
Rhodexin A," Org. Lett. 2008, 10,
3647-3649. [pdf]
259. M. E. Jung, J. A. Berliner, L. Koroniak, A. D. Watson, and B. G. Gugiu,
"Improved Synthesis of the Epoxy Isoprostane Phospholipid PEIPC and its
Reactivity with Amines," Org. Lett. 2008, 10,
4207-4209. [pdf]
260. M. E. Jung and D. A. Allen, "Use of 4-Cyanocoumarins as Dienophiles in a Facile
Synthesis of Highly Substituted Dibenzopyranones," Org. Lett. 2009,
11, 757-760.[pdf]
261. M. E. Jung and F. Perez, "Synthesis of 2-Substituted 7-Hydroxybenzofuran-4-carboxylates
via Addition of Silyl Enol Ethers to o-Benzoquinone Esters," Org. Lett.
2009, 11, 2165-67. [pdf]
262. C. Tran, S. Ouk, N. J. Clegg, Y. Chen, P. A. Watson, V. Arora, J. Wongvipat, P. M.
Smith-Jones, D. Yoo, A. Kwon, T. Wasielewska, D. Welsbie, C. Chen, C. S. Higano, T. M.
Beer, D. T. Hung, H. I. Scher, M. E. Jung, and C. Sawyers, "Development of a
Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer," Science
2009, 324, 787-790. [pdf]
263. M. E. Jung, J. Cordova, and M. Murakami, "Total Synthesis of (±)-Kellermanoldione:
Stepwise Cycloaddition of a Functionalized Diene and Allenoate," Org.
Lett. 2009, 11, 3882-3885. [pdf]
264. N. Suree, C. K. Liew, V. Villareal, W. Thieu, E. A. Fadeev, J. J.
Clemens, M. E. Jung and R. T. Clubb, "The Structure of the Staphylococcus aureus
Sortase-Substrate Complex Reveals How the Universally Conserved LPXTG Sorting Signal
is Recognized," J. Biol. Chem. 2009, 284, 24465-24477. [pdf]
265. L. Du, R. Damoiseaux, S. Nahas, J. Pollard, J. Goldstine, H. Hu, M. E. Jung,
R. A. Gatti, "Identification of compounds with the ability to induce readthrough
of nonsense mutations," J. Experimental Med.
2009, 206, 2285-2297. [pdf]
266. N. Suree, S. W. Yi, W. Thieu, M. Marohn, R. Damoiseaux, A. Chan, M. E. Jung and
R. T. Clubb, "Discovery and Structure Activity Relationship Analysis of Staphylococcus
aureus Sortase A Inhibitors," Bioorg. Med. Chem. 2009, 7174-7185. [pdf]
267. M. E. Jung and R. Salehi-Rad, "Total Synthesis of Auripyrone A Using a
Tandem Non-Aldol Aldol-Paterson Aldol Process as a Key Step," Angew.
Chem. 2009 48, 8766-8769. [pdf]
268. M. E. Jung and G-Y. Im, "The Total Synthesis of Racemic Laurenditerpenol, an HIF-1
Inhibitor," J. Org. Chem. 2009, 74, 8739-8753. [pdf]
269. M. C. Wolf, A. N. Freiberg, T.-H. Zhang, Z. Akyol-Ataman, A. Grock, P. W. Hong,
J. Li, N. F. Watson, A. Q. Fang, H. C. Aguilar, M. Porotto, A. N. Honko, R. Damoiseaux,
J. P. Miller, S. E. Woodson, S. Chantasirivisal, V. Fontanes, O. A. Negrete, P. Krogstad,
A. Dasgupta, A. Moscona, L. E. Hensley, S. P. Whenlan, K. F. Faull, M. R. Holbrook,
M. E. Jung, and B. Lee, "A Broad-spectrum Antiviral Targeting Entry of Enveloped Viruses,"
Proceedings of the National Academy of Sciences of the United States of America
(PNAS) 2010, 107, 3157-62. [pdf]
270. M. E. Jung, S. Ouk, D. Yoo, C. L. Sawyers, C. Chen, C. Tran, and J. Wongvipat,
"Structure-Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for
Castration-Resistant Prostate Cancer (CRPC)," J. Med. Chem. 2010, 53, 2779-2796.
[pdf]
271. J. S. Johnson, V. Meliton, W. K. Kim, K. B. Lee, J. C. Wang, K. Nguyen, D. Yoo,
M. E. Jung, E. Atti, S. Tetradis, R. C. Pereira, T. J. Hahn, F. Farouz, S. Thies and
F. Parhami, "Novel Osteogenic Oxysterols Induce Osteogenic and Inhibit Adipogenic
Differentiation of Marrow Stromal Cells In Vitro and Stimulate Bone Formation and
Spinal Fusion In Vivo," Am. Soc. Bone Mineral Res. 2010, Abstract 210.
[pdf]
272. M. E. Jung, M. Chaumontet, and R. Salehi-Rad, "Total Synthesis of Auripyrone B Using
a Non-Aldol Aldol-Cuprate Opening Process," Org. Lett. 2010, 12, 2872-2875.
[pdf]
273. M. E. Jung and J. J. Chang, "Enantiospecific Formal Total Synthesis
of (+)-Fawcettimine," Org. Lett. 2010, 12, 2962-2965. [pdf]
274. M. Aghajan, N. Jonai, F. Fu, K. Flick, M. Luo, X. Cai, I. Ouni, N. Pierce, R. Hao,
B. Lomenick, R. Damoiseaux, R. Verma, Y. Li, C. Li, K. N. Houk, M. E. Jung, L. Huang,
R. J. Deshaies, P. Kaiser, and J. Huang, "Chemical Genetics of TOR Identifies an SCF
Family E3 Ubiquitin Ligase Inhibtior," Nature Biotechnology 2010, 28, 738-742. [pdf]
275. M. E. Jung and R. Salehi-Rad, "Dipyrone Approach toward the Synthesis of the Cytotoxic Natural
Product Auripyrone A," Tetrahedron Lett. 2010, 50, 4931-4933. [pdf]
276. W. Xu, X. Cai, M. E. Jung, and Y. Tang, "Analysis of Intact and Dissected Fungal Polyketide Synthase-Nonribosomal
Peptide Synthetase in vitro and in Saccharomyces cerevisiae," J. Am. Chem. Soc. 2010, 132, 13604-13607.
[pdf]
277. M. E. Jung, T.-H. Zhang, R. M. Lui, O. Gutierrez, and K. N. Houk, "Synthesis of a trans, syn, trans
Dodecahydrophenanthrene via a Bicyclic Transannular Diels-Alder (BTADA) Reaction: Intermediate for
the Synthesis of Fusidic Acid," J. Org. Chem. 2010, 75, 6933-6940. [pdf]
278. M. E. Jung and R. M. Lui, "Studies toward the Syntheses of Cucurbitacins B and D,"
J. Org. Chem. 2010, 75, 7146-7158. [pdf]
279. F. Vigant, M. E. Jung, and B. Lee, "Positive Reinforcement for Viruses,"
Chem. Biol. 2010, 17, 1049-1051. [pdf]
280. M. E. Jung and T. A. Dong, "Improved Synthesis of 4-Amino-7-nitrobenz-2,1,3-oxadiazoles using NBD Fluoride,"
Tetrahedron Lett. 2011, 52, 2533-2535. [pdf]
281. J. Johnson, V. Meliton, W. K. Kim, K. B. Lee, J. Wang, K. L. Nguyen, D. Yoo, M. E. Jung,
E. Atti, S. Tetradis, R. Pereira, C. Magyar, T. Nargizyan, T. Hahn, F. Farouz, S. Thies, and F. Parhami,
"Novel Oxysterols Have Pro-Osteogenic and Anti-Adipogenic Effects In Vitro and Induce Spinal Fusion In Vivo"
J. Cellular Biochem. 2011, 112, 1673-1684. [pdf]
282. M. E. Jung and D. Yoo, "First Total Synthesis of Rhodexin A," Org. Lett. 2011,
13, 2698-2701. [pdf]
283. H. Wang, K. N. Houk, D. A. Allen, and M. E. Jung, "Computational Elucidation of the Origins of Reactivity and
Selectivity in Non-Aldol Aldol Rearrangements of Cyclic Epoxides," Org. Lett. 2011,
13, 3238-3241. [pdf]
284. K. Kim, R. Damoiseaux, A. J. Norris, L. Rivina, K. Bradley, M. E. Jung, R. A. Gatti, R. H. Schiestl, W. H. McBride,
"High Throughput Screening of Small Molecule Libraries for Modifiers of Radiation Responses," Int. J. Radiat. Biol.
2011, 87, 839-845. [pdf]
285. M. E. Jung and P. Koch, "An Efficient Synthesis of the Protected Carbohydrate Moiety of Brasilicardin A,"
Org. Lett. 2011, 13, 3710-3713. [pdf]
286. M. E. Jung and H. V. Chu, "Synthesis of BCD Tricylic Analogues of the Novel Cardiac Glycoside Rhodexin A,"
Tetrahedron Lett. 2011, 52, 4312-4314. [pdf]
287. M. E. Jung, J.-M. Ku, L. Du, H. Hu, and R. A. Gatti, "Synthesis and Evaluation of Compounds that
Induce Readthrough of Premature Termination Codons," Bioorg. Med. Chem. Lett.
2011, 21, 5842-5848. [pdf]
288. M. E. Jung and P. Koch, "Mild and Selective Deprotection of PMB Ethers with Triflic Acid in Dichloromethane,"
Tetrahedron Lett. 2011, 52, 6051-6054. [pdf]
289. M. E. Jung and D. Yoo, "Stereoselective Synthesis of a Fully Protected C13-C23 Fragment of Tedanolide,"
Tetrahedron 2011, 67, 10281-10286. [pdf]
290. C. F. Regan, F. Pierre, M. K. Schwaebe, M. Haddach, M. E. Jung, and D. M. Ryckman, "A Facile Synthesis of
5-Halopyrimidine-4-carboxylic Acid Esters via a Minisci Reaction," Synlett 2012, 443-447. [pdf]
291. M. E. Jung, W.-J. Kim, N. K. Avliyakulov, M. Oztug, and M. J. Haykinson, "Synthesis and Validation
of Cyanine-Based Dyes for DIGE," Ch. 6, "Differential Gel Electrophoresis (DIGE)," Springer-Verlag, 2012, pp. 67-88.
[pdf]
292. N. J. Clegg, J. Wongvipat, C. Tran, S. Ouk, A. Dilhas, Y. Chen,K. Grillot, E. Bischoff, L. Cai, A. Aparicio, J. Kaufman,
V. Arora, G. Shao, J. Qian, H. Zhao, G. Yang, J. Sensintaffar, T. Wasielewska, H. I. Scher, P. Smith-Jones, C. Bonnefous,
J. Joseph, D. Darimont, M. Klang, E. De Stanchina, N. Wu, N. D. Smith, O. Ouerfelli, P. Rix, R. A. Heyman, M. E. Jung,
C. Sawyers, and J. H. Hager, "Discovery and development of ARN-509, a novel Anti-androgen for the Treatment of Prostate
Cancer," Cancer Research 2012, 72, 1494-1503. [pdf]
293. M. E. Jung and S. W. Yi, "Efficient Synthesis of threo β-Aminoalcohols from Amino-aldehydes via Chelation-controlled
Additions. Total Synthesis of L-threo Sphingosine and Safingol,” Tetrahedron Lett. 2012, 53, 4216-4220.
[pdf]
294. F. Stappenbeck, W. Xiao, M. Epperson, M. Riley, A. Priest, D. Huang, K. Nguyen, M. E. Jung, R. S. Thies and F. Farouz,
"Novel Oxysterols Activate the Hedgehog Pathway and Induce Osteogenesis," Bioorg. Med. Chem. Lett. 2012, 22,
5893-5897. [pdf]
295. R. Kayali, J.-M. Ku, G. Khitrov, M. E. Jung, O. Prikhodko, and C. Bertoni, "Read-through compound 13 restores
dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy,"
Hum. Mol. Genet. 2012, 21, 4007-4020. [pdf]
296. M. E. Jung and J. J. Chang, "Total Synthesis of the Proposed Structure of Mycosporulone: Structural Revision and
an Unexpected Retro-Aldol–Aldol Reaction," Org. Lett. 2012, 14, 4898-4901. [pdf]
297. M. E. Jung and M. Guzaev, "Trimethylaluminum-Triflimide Complexes for the Catalysis of Highly Hindered Diels-Alder
Reactions," Org. Lett. 2012, 14, 5169-5171. [pdf]
298. M. E. Jung and G. Deng, "Facile Synthesis of the 1-Monoester of 2-Ketoalkanedioic Acids,
for example, α-Ketoglutarate," J. Org. Chem. 2012, 77, 11002-11005. [pdf]
299. M. E. Jung, F. Perez, C. F. Regan, S.-W. Yi, Q. Perron, "Phenylseleno Acrylate: New Ethylene Equivalent for
Diels-Alder Reactions," Angew. Chem. 2013, 52, 2060-2062. Corrigendum: Angew. Chem.
2013, 52, 11963. [pdf]
300. K. J. Williams, J. P. Argus, Y. Zhu, M. Q. Wilks, B. N. Marbois, A. G. York, Y. Kidani, A. L. Pourzia, D. Akhavan,
D. N. Lisiero, E. Komisopoulou, A. H. Henkin, H. Soto, B. T. Chamberlain, L. Vergnes, M. E. Jung, J. Z. Torres, L. M. Liau,
H. R. Christofk, R. M. Prins, P. S. Mischel, K. Reue, T. G. Graeber, and S. J. Bensinger, "An essential requirement for
the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity," Cancer Res. 2013, 73, 2850-2862.
[pdf]
301. F. Vigant, J. Lee, A. Hollmann, L. Tanner, Z. Akyol-Ataman, G. Shui, H. Aguilar-Carreno, T. Yun, D. Zhang, D. Meriwether,
G. Roman-Sosa, L. Robinson, T. Juelich, H. Buczkowski, S. Chou, M. A. R. B. Castanho, M. C. Wolf, A. Banyard, M. Kielian,
S. Reddy, M. R. Wenk, M. Selke, N. C. Santos, A. Freiberg, M. E. Jung, and B. Lee, "A Mechanistic Paradigm for
Broad-Spectrum Antivirals that Target Virus-cell Fusion," PLOS Pathog. 2013, 9, e1003297.
[pdf]
302. M. E. Jung and M. Guzaev, "Studies Toward the Enantiospecific Total Synthesis of Rhodexin A,"
J. Org. Chem. 2013, 78, 7518-7526. [pdf]
303. J. M. Murphy, A. L. Armijo, C. H. Lee, D. O. Campbell, Z. Li, H.-I Liao, J. T. Lee, D. Nathanson, W. R. Austin,
J. Nomme, R. Darvish, T. Smith, Y. Su, H. R. Herschman, A. Alexandrova, S. Sadeghi, M. E. Phelps, A. Lavie, M. E. Jung,
J. Czernin, N. Satyamurthy, and C. G. Radu, "Development of new deoxycytidine kinase inhibitors and non-invasive in vivo
evaluation using Positron Emission Tomography," J. Med. Chem. 2013, 56, 6696-6708.
[pdf]
304. L. Du, M. E. Jung, R. Damoiseaux, G. Completo, F. Fike, J.-M. Ku, S. Nahas, C. Pao, H. Hu, and R. A. Gatti,
"A new series of novel small molecular weight compounds induce readthrough of all three types of nonsense mutations
in the ATM gene," Molec. Ther. 2013, 21, 1653-1660. [pdf]
305. A. H. Chan, J. Wereszczynski, B. R. Amer, S. W. Yi, M. E. Jung, R.T. Clubb, and J. A. McCammon, "Discovery of
Staphylococcus aureus Sortase A Inhibitors Using Virtual Screening and the Relaxed Complex Scheme,"
Chem. Biol. Drug Des. 2013, 82, 418-428. [pdf]
306. W. Zhong, J. R. Springstead, R. Al-Mubarak, S. Lee, R. Li, B. Emert, J. A. Berliner, and
M. E. Jung, "An Epoxyisoprostane is a Major Regulator of Endothelial Cell Function,"
J. Med. Chem. 2013, 56, 8521-8532. [pdf]
307. M. E. Jung, M. Trzoss, J. M. Tsay, and S. Weiss, "A Bis-Phosphine Modified Peptide Ligand for Stable and
Luminescent Quantum Dots in Aqueous Media," Synthesis 2013, 2426-2430. [pdf]
308. X. Rong, C. J. Albert, C. Hong, M. A. Duerr, B. T. Chamberlain, E. J. Tarling, A. Ito, J. Gao,
B. Wang, P. A. Edwards, M. E. Jung, D. A. Ford, and P. Tontonoz, "LXRs regulate ER stress and
inflammation through dynamic modulation of membrane phospholipid composition," Cell Metab.
2013, 18, 685-697. [pdf]
309. E. J. Gillespie, C.-L. Ho, K. Balaji, Z. Li, D. Thomas, D. L. Clemens, G. Deng, Y. Wang,
H. Elsaesser, B. Tamilselvam, B. France, B. T. Chamberlain, S. R. Blanke, G. Cheng, D. Brooks,
M. E. Jung, M. Manchester, J. Zink, J. Colicelli, R. Damoiseaux, and K. A. Bradley, "Selective
Inhibitor of Endosomal Trafficking Pathways Exploited by Multiple Toxins and Viruses,"
Proc. Natl. Acad. Sci. U.S.A., 2013, P110, E4904-E4912, SE4904/1-SE4904/4.
[pdf]
310. D. M. Janzen, D. Y. Paik, M. A. Rosales, B. Yep, D. Cheng, O. N. Witte, H. Kayadibi,
C. M. Ryan, M. E. Jung, K. Faull, and S. Memarzadeh, "Tumor sensitivity to poly(ADP-ribose)
polymerase (PARP) inhibition in vivo is regulated by circulating levels of estrogen," Mol. Cancer
Ther. 2013, 12, 2917-2928. [pdf]
311. J. Majer, J. Jurczak, P. Kwiatkowski, L. Cotarca, M. E. Jung , and J.-C. Caille,
"Asymmetric synthesis of (-)-bissetone via a highly enantioselective hetero-Diels-Alder
reaction," Tetrahedron 2013, 69, 8463-8469; see Corrigendum: Tetrahedron
2018, 74, 1580. [pdf1] [pdf2]
312. K.-D. Kim, S. Srikanth, Y.-V. Tan, M.-K. Yee, M. Jew, R. Damoiseaux, M. E. Jung, S. Shimizu, D. S. An,
B. Ribalet, J. A. Waschek, and Y. Gwack, "Calcium Signaling via Orai1 is Essential for Induction of Nuclear
Orphan Receptor Pathway to drive Th17 Differentiation," J. Immunol. 2014, 192, 110-122.
[pdf]
313. F. Vigant, A. Hollmann, J. Lee, N. Santos, M. E. Jung, and B. Lee, "The Rigid Amphipathic Fusion Inhibitor
dUY11 Acts through Photosensitization of Viruses," J. Virol. 2014, 88, 1849.
[pdf]
314. X. Yan, S. Lee, B. G. Gugiu, L. Koroniak, Michael E. Jung, J. Berliner, J. Cheng, and R. Li, "Fatty Acid
Epoxyisoprostane E2 Stimulates an Oxidative Stress Response in Endothelial Cells," Biochem. Biophys. Res. Commun.
2014, 444, 69-74. [pdf]
315. D. A. Nathanson, A. L. Armijo, M. Tom, Z. Li, E. Dimitrova, W. R. Austin, J. Nomme, D. O. Campbell, L. Ta,
T. M. Le, J. T. Lee, R. Darvish, A. Gordin, L. Wei, H.-I. Liao, M. Wilks, C. Martin, S. Sadeghi, J. M. Murphy,
N. Boulos, M. E., Phelps, K. F. Faull, H. R. Herschman, M. E. Jung, J. Czernin, A. Lavie, and C. G. Radu,
"Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication," J. Exper. Med.
2014, 211, 473-486. [pdf]
316. M. E. Jung, B. T. Chamberlain, C.-L. Ho, E. J. Gillespie, and K. A. Bradley, "Photoaffinity
Probes Developed from Structure-Activity Relationship Study Function as Irreversible Inhibitors
of Anthrax Lethal Toxin," ACS Med. Chem. Letts. 2014, 5, 363-367. [pdf]
317. N. M. Evdokimov, G. Flores, P. M. Clark, M. E. Phelps, O. N. Witte, and M. E. Jung, "5-(2-[18F]Fluoroethyl)-4-methylthiazole
Probe for Positron Emission Tomography of the Central Nervous System," Chem. Heterocycl. Compd. 2014, 330-334.
[pdf]
318. A. W. Jacobitz, J. Wereszczynski, S. W. Yi, B. R. Amer, G. L. Huang, A. V. Nguyen, M. R. Sawaya, M. E. Jung,
J. A. McCammon, and R.T. Clubb, "Structural and computational studies of the Staphylococcus aureus Sortase B-substrate
complex reveal a substrate-stabilized oxyanion hole," J. Biol. Chem. 2014, 289, 8891-8902.
[pdf]
319. M. E. Jung and G. Deng, "Synthesis of α-Diketones from Alkyl Aryl and Diarylalkynes using Mercuric Salts" Org. Lett.
2014, 16, 2142-2145. [pdf]
320. M. E. Jung, G. S. Lee, H. V. Pham, and K. N. Houk, "Palladium Hydride Promoted Stereoselective Isomerization of Unactivated
Di-(Exo)methylenes to Endocyclic Dienes," Org. Lett. 2014, 16, 2382-2385. [pdf]
321. T. Sallam, A. Ito, X. Rong, J. Kim, C. van Stijn, B. T. Chamberlain, M. E. Jung, L. C. Chao, M. Jones, T. Gilliland, X. H. Wu,
G. L. Su, R. K. Tangirala, P. Tontonoz, and C. Hong, "The macrophage LBP gene is an LXR target that promotes macrophage survival and
atherosclerosis," J. Lipid Res., 2014, 55, 1120-1130. [pdf]
322. R. Chin, M. Pai, X. Fu, S. Diep, G. Jung, B. Lomenick, G. Deng, S. A. Whelan, G. C., Monsalve, H. R. Chang,
C. F. Clarke, A. R. Frand, M. E. Jung, and J. Huang, "Alpha-ketoglutarate extends lifespan in Caenorhabditis elegans
by a novel mechanism mediated by the ATP synthase and TOR," Nature, 2014, 510 (7505), 397-401.
[pdf]
323. P. M. Clark, G. Flores, N. M. Evdokimov, M. N. McCracken, T. Chai, E. Nair-Gill, F. O’Mahony, S. W. Beaven, K. F. Faull,
M. E. Phelps, M. E. Jung, and O. N. Witte, "Positron emission tomography probe demonstrates a striking concentration of ribose salvage
in the liver," Proc. Natl. Acad. Sci. U.S.A. 2014, 111, E2866-E2874. [pdf]
324. M. E. Jung, T. A. Dwight, F. Vigant, M. E. Østergaard, E. S. Swayze, and P. P. Seth, "Synthesis and Duplex Stabilizing
Properties of Fluorinated N-Methanocarbathymidine Analogs," Angew. Chem. 2014, 53, 9893-9897.
[pdf]
325. S. R. Montgomery, T. Nargizyan, V. Meliton, S. Nachtergaele, R. Rohatgi, F. Stappenbeck, M. E. Jung,
J. S. Johnson, B. Aghdasi, H. Tian, G. Weintraub, H. Inoue, E. Atti, S. Tetradis, R. C. Pereira, A. Hokugo, R. Alobaidaan, Y. Tan,
T. J. Hahn, J. C. Wang, F. Parhami, "A Novel Osteogenic Oxysterol Compound for Therapeutic Development to Promote Bone Growth:
Activation of Hedgehog Signaling and Osteogenesis through Smoothened Binding," J. Bone Miner. Res. 2014, 29, 1872-1885.
[pdf]
326. M. E. Østergaard, T. A. Dwight, A. Berdeja, E. S. Swayze, M. E. Jung, and P. P. Seth, "A Comparison of Duplex Stabilizing
"Properties of 2’-Fluorinated Nucleic Acid Analogs with Furanose and Non-Furanose Sugar Rings," J. Org. Chem. 2014,
79, 8877-8881.
[pdf]
327. M. E. Jung and G. S. Lee, "Efficient Synthesis of Highly Substituted Adamantanones from Bicyclo[3.3.1]nonanes," J. Org. Chem.
2014, 79, 10547-10552.
[pdf]
328. J. Nomme, Z. Li, R. M. Gipson, J. Wang, A. L. Armijo, T. Le, S. Poddar, T. Smith, B. D. Santarsiero, H.-A. Nguyen, J. Czernin,
A. N. Alexandrova, M. E. Jung, C. G. Radu, and A. Lavie, "Structure-guided development of deoxycytidine kinase inhibitors with
nanomolar affinity and improved metabolic stability," J. Med. Chem. 2014, 57, 9480-9494.
[pdf]
329. C. Hong, S. M. Marshall, A. L. McDaniel, M. Graham, J. D. Layne, L. Cai, E. Scotti, R. Boyadjian, J. Kim, B. T. Chamberlain,
R. K. Tangirala, M. E. Jung, L. Fong, R. Lee, S. G. Young, R. E. Temel, and P. Tontonoz, "The LXR-Idol Axis Differentially Regulates
Plasma LDL Levels in Primates and Mice," Cell Metab. 2014, 20, 910-918.
[pdf]
330. M. Manoharan, K. N. Jayaprakash, J. Willoughby, A. Chan, K. Charisse, R. Alam, Q. Wang, M. Hoekstra, P. Kandasamy, A. Kelin,
S. Milstein, N. Taneja, J. O’Shea, S. Shaikh, L. Zhang, R. van der Sluis, T. van Berkel, M. E. Jung, A. Akinc, R. Hutabarat,
S. Kuchimanchi, Satya; K. Fitzgerald, T. Zimmermann, M. Maier, R. Kallanthottathil, "Multivalent N-Acetylgalactosamine-Conjugated
siRNA Localizes in Hepatocytes and Elicits Robust RNAi-mediated Gene Silencing," J. Am. Chem. Soc. 2014,
136, 16958-16961.
[pdf]
331. J. Escamilla, C. Liu, S. Priceman, J. Sung, F. Pouliot, C. Magyar, Z. Jiang, J. Xu, G. Deng, B. West, G. Bollag, Y. Fradet,
L. Lacombe, M. E. Jung, J. Huang, and L. Wu, "CSF1 Receptor Targeting In Prostate Cancer Reverses Macrophage-Mediated Resistance
to Androgen Blockade Therapy," Cancer Res., 2015, 75, 950-962.
[pdf]
332. M. E. Jung and D. L. Sun, "Trapping of Payne Rearrangement Intermediates with Arylselenide Anions," Tetrahedron Lett.
2015, 56, 3082-3085.
[pdf]
333. N. M. Evdokimov, P. M. Clark, G. Flores, T. Chai, K. F. Faull, M. E. Phelps, O. N. Witte and M. E. Jung,
"[18F]-2-Deoxy-2-fluororibose is a sensitive PET probe for studying liver function in vivo," J. Med. Chem.
2015, 58, 5538-5547.
[pdf]
334. M. E. Jung, B. T. Chamberlain, P. Koch, and K. V. Niazi, "Synthesis and Bioactivity of a Brasilicardin A Analogue Featuring a
Simplified Core," Org. Lett. 2015, 17, 3608-3611.
[pdf]
335. X. Fu, R. M. Chin, L. Vergnes, H. Hwang, G. Deng, Y. Xing, M. Y. Pai, S. Li, L. Ta, F. Fazlollahi, C. Chen, R. M. Prins,
M. A. Teitell, D. A. Nathanson, A. Lai, K. F. Faull, M. Jiang, S. G. Clarke, T. F. Cloughesy, T. G. Graeber, D. Braas, H. R. Christofk,
M. E. Jung, K. Reue, and J. Huang, "2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling," Cell Metab. 2015, 22, 508-515.
[pdf]
336. Chan, A. H.; Yi, S. W.; Terwilliger, A. L.; Maresso, A. W.; Jung, M. E. and Clubb, R. T., "Structure of the Bacillus anthracis sortase
A enzyme bound to its sorting signal: a flexible amino-terminal appendage modulates substrate access," J. Biol. Chem. 2015, 290,
25461-25474.
[pdf]
337. M. E. Jung, C. A. Roberts, F. Perez, H. V. Pham, L. Zou, K. N. Houk, "Thermodynamic Control of Isomerizations
of Bicyclic Radicals: The Interplay of Ring Strain and Radical Stabilization," Org. Lett. 2016, 18,
32-35.
[pdf]
338. J. Y. Chen, C. Tran, L. Hwang, G. Deng, M. E. Jung, K. F. Faull, M. S. Levine, and C. Cepeda, "Partial Amelioration of
Peripheral and Central Symptoms of Huntington’s Disease via Modulation of Lipid Metabolism," J. Huntingtons Dis. 2016, 5, 65-81.
[pdf]
339. B. Holmes, J. Lee, K. A. Landon, A. Benavides-Serrato, T. Bashir, M. E. Jung, A. Lichtenstein, and J. Gera,
"Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced IRES-mediated Translation of Cyclin D1 and c-MYC to Treat Glioblastoma,"
J. Biol. Chem. 2016, 291, 14146-14159. [pdf]
340. A. W. Jacobitz, E. B. Naziga, S. W. Yi, S. A. McConnell, R. Peterson, M. E. Jung, R. T. Clubb, and J. Wereszczynski,
"The “lid” in the Streptococcus pneumoniae SrtC1 sortase adopts a rigid structure that regulates substrate access to the active site,"
J. Phys. Chem. B 2016, 120, 8302-8312. [pdf]
341. M. E. Jung, D. L. Sun, T. A. Dwight, P. Yu, W. Li, and K. N. Houk, "Synthesis of 2-Ethenylcyclopropyl Aryl
Ketones via Intramolecular SN2-like Displacement of an Ester,"
Org. Lett. 2016, 18, 5138-5141. [pdf]
342. Y. Shi, T. R. Daniels-Wells, P. Frost, J. Lee, R. S. Finn, C. Bardeleben, M. L. Penichet, M. E. Jung, J. Gera, and A. Lichtenstein,
"An Inhibitor of DEPTOR-mTOR Binding Induces Significant Cytotoxicity against Multiple Myeloma Cells,"
Cancer Res. 2016, 76, 5822-5831. [pdf]
343. B. F. Balmer, R. L. Powers, T. Zhang, J. Lee, F. Vigant, B. Lee, M. E. Jung,
M. K. Purcell, K. Snekvik and H. C. Aguilar, "Inhibition of an aquatic rhabdovirus
demonstrates promise of a broad-spectrum antiviral for use in aquaculture," J. Virol.
2017, 91, e02181-16/1-e02181-16/12. [pdf]
344. A. Benavides-Serrato, J. Lee, B. Holmes, K. A. Landon, T. Bashir, M. E. Jung,
A. Lichtenstein, and J. Gera, "Specific blockade of Rictor-mTOR association inhibits
mTORC2 activity and is cytotoxic in glioblastoma," PLOS One 2017, 12,
e0176599. [pdf]
345. M. E. Østergaard, J. Nichols, T. A. Dwight, W. Lima, M. E. Jung, E. S. Swayze,
and P. P. Seth, "Fluorinated Nucleoside Modifications Modulate Allel Selectivity of
SNP Targeting Antisense Oligonucleotides," Mol. Ther.--Nucleic Acids 2017,
7, 20-30.[pdf]
346. A. H. Chan, S. W. Yi, E. M. Weiner, B. R. Amer, C. Sue, J. Wereszczynski, C. Dillen, S. Senese, J. Z. Torres, J. A. McCammon,
L. S. Miller, M. E. Jung, and R. T. Clubb, "NMR Structure-Based Optimization of Staphylococcus aureus Sortase A Pyridazinone Inhibitors,"
Chem. Biol. Drug Des. 2017, 90, 327-344.[pdf]
347. E. D. Micewicz, K. Kim, K. S. Iwamoto, J. A. Ratikan, G. Cheng, G. M. Boxx, R. D. Damoiseaux,
J. P. Whitelegge, P. Ruchala, C. Nguyen, J. Loo, G. Deng, M. E. Jung, J. W. Sayre, A. J. Norris,
D. Schaue, and W. H. McBride, "4-(Nitrophenylsulfonyl)piperazines Mitigate Radiation Damage to Multiple Tissues,"
PLOS One 2017, 12, e0181577. [pdf]
348. J. Lee, Y. Shi, M. Vega, Y. Yang, J. Gera, M. E. Jung, and A. Lichtenstein, "Structure-Activity Relationship
Study of Small Molecule Inhibitors of the DEPTOR-mTOR Interaction,"
Bioorg. Med. Chem. Lett. 2017, 27, 4714-4724. [pdf]
349. J. Cinkornpumin, M. Roos, L. Nguyen, X. Liu, X. Gaeta, S. Lin, D. N. Chan, A. Liu,
R. I. Gregory, M. E. Jung, J. Chute, H. Zhu, and W. E. Lowry, "A small molecule screen to
identify regulators of let-7 targets," Scientific Reports 2017, 7,
Article number: 15973 (doi:10.1038/s41598-017-16258-9). [pdf]
350. Y. Xing, J. Zuo, P. A. Krogstad, and M. E. Jung, "Synthesis and SAR Studies of Novel
Pyrazolopyridine Derivatives as Inhibitors of Enterovirus Replication," J. Med. Chem.
2018, 61, 1688-1703. [pdf]
351. B. F. Balmer, R. G. Getchell, R. L. Powers, T. Zhang, J. Lee, M. E. Jung, M. K. Purcell, K. Snekvik
and H. C. Aguilar, "Broad-spectrum antiviral JL122 blocks infection and inhibits transmission of aquatic
rhabdoviruses," Virology 2018, 525, 143-149. [pdf]
352. J. Campagna, P. Spillman, B. Jagodzinska, D. Bai, A. Hatami, C. Zhu, T. Bilousova, M. Jun, C. J, Elias, J. Pham, M. E. Jung,
D. E. Bredesen, and V. John, "A Small Molecule ApoE4-targeted Therapeutic Candidate that Normalizes Sirtuin1
Levels and Improves Cognition in an Alzheimer’s disease Mouse Model," Scientific Reports
2018, 8, 1-15 (doi:10.1038/s41598-018-35687-8). [pdf]
353. N. G. R. Dayan Elshan, M. B. Rettig, and M. E. Jung, "Molecules Targeting the Androgen Receptor (AR) Signaling Axis
Beyond the AR‐Ligand Binding Domain," Med. Res. Rev. 2019, 39, 1-52. [pdf]
354. E. D. Micewicz, K. S. Iwamoto, J. A. Ratikan, C. Nguyen, M. W. Xie, G. Cheng, G. M. Boxx, E. Deriu,
R. D. Damoiseaux, J. P. Whitelegge, P. P. Ruchala, R. Avetisyan, M. E. Jung, G. Lawson, E. Nemeth, T. Ganz,
J. W. Sayre, W. H. McBride, and D. Schaue, "The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome
and its Mitigation," Radiation Res. 2019, 191, 323-334. [pdf]
355. E. A. Shimizu, B. Cory, J. Hoang, G. G. Castro, M. E. Jung, and D. A. Vosburg, "Aqueous Dearomatization/Diels-Alder
Cascade to a Grandifloracin Precursor," J. Chem. Ed. 2019, 96, 998–1001. [pdf]
356. D. C. Márquez-Garban, G. Deng, B. Comin-Anduix, A. J. Garcia, E. Diers, G. Ma, N. Hamilton, M. E. Jung,
and R. J. Pietras, "Selective estrogen receptor downregulators and immune checkpoint inhibitors in breast cancer
immunotherapy," AACR Annual meeting, Atlanta, GA, Cancer Res. 2019, 79 (13), Abstract 1012. [pdf]
357. M. E. Jung and H. J. Gim, "Formation of Aryl (1-Cyano-4-(dialkylamino)butadienyl) Ketones from Pyridines,"
Synthesis 2019, 51, 2548-2552. [pdf]
358. N. G. R. Dayan Elshan, M. B. Rettig, and M. E. Jung, "Synthesis of β-Amino Diaryldienones Using the Mannich
Reaction," Org. Lett. 2019, 21, 4039-4043. [pdf]
359. D. Márquez-Garbán, G. Deng, B. Comin-Anduix, A. J. Garcia, Y. Xing, H.-W. Chen, G. Cheung-Lau, N. Hamilton, M. E. Jung,
R. Pietras, "Antiestrogens in combination with immune checkpoint inhibitors in breast cancer immunotherapy,"
J. Steroid Biochem. Mol. Biol. 2019, 193, 105415. [pdf]
360. Y. Zhang, M. Roos, M. Quarmyne, M. Li, K. Pohl, H. Himburg, E. Diers, H. J. Gim, R. Damoiseaux, J. Whitelegge, W. McBride,
M. E. Jung, J. P. Chute, "Inhibition of Protein Tyrosine Phosphatase – Sigma Promotes Hematopoietic Stem Cell Regeneration,"
Nature Commun. 2019, 10, Article number: 3667. [pdf]
361. M. I. Vega, Y. Shi, P. Frost, S. Huerta-Yepez, G. Antonio-Andres, R. Hernández-Pando, J. Lee, M. E. Jung, J. F. Gera,
and A. Lichtenstein, "A novel drug induces DEPTOR degradation in myeloma cells with resulting tumor cytotoxicity"
Mol. Cancer Ther. 2019, 18 (10), 1822-1831. [pdf]
362. E. R. Abt, E. W. Rosser, M. A. Durst, V. Lok, S. Poddar, T. M. Le, A. Cho, W. Kim, L. Wei, J. Song, J. R. Capri, S. Xu, N. Wu,
R. Slavic, M. E. Jung, R. Damoiseaux, J. Czernin, T. R. Donahue, A. Lavie, C. G. Radu, "Metabolic Modifier Screen Reveals Secondary
Targets of Protein Kinase Inhibitors within Nucleotide Metabolism," Cell Chem. Biol. 2020, 27, 1-9. [pdf]
363. K. M. Cheung, K.-A. Yang,. N. Nakatsuka, C. Zhao, M. Ye, M. E. Jung, H. Yang, P. S. Weiss, M. N. Stojanović, and A. M. Andrews,
"Phenylalanine Monitoring via Aptamer-Field-Effect Transistor Sensors," ACS Sensors 2019, 4 (12), 3308-3317. [pdf]
364. D. L. Sun, S. Poddar, R. D. Pan, E. W. Rosser, E. R. Abt, J. Van Valkenburgh, T. M. LE, V. Lok, J. Capri, S. P. Hernandez, J. Song, J. Li,
A. Turlik, X. Chen, C.-A. Cheng, W. Chen, C. E. Mona, A. D. Stuparu, L. Vergnes, K. Reue, R. Damoiseaux, J. I. Zink, J. Czernin, T. R.Donahue,
K. N. Houk, M. E. Jung, and C. G. Radu, "Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive
leukemia," ChemRxiv 2019, 1-12; RSC Medicinal Chemistry 2020, 11 (3), 392-4110. [pdf]
365. S. Poddar, E. Capparelli, E. W. Rosser, R. M. Gipson, L. Wei, T. Le, M. E. Jung, C. Radu, M. Nikanjam, "Development and preclinical
pharmacology of a novel dCK inhibitor, DI-87," Brit. J. Pharmacol. 2020, 172, 113742. [pdf]
366. J. Tsang, L. Urner, G. Kim, K. Chow, L. Baufeld, K. Faull, T. Cloughesy, P. Clark, M. E. Jung, D. Nathanson,
"Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor Against Malignant Brain Tumors,"
ACS Med. Chem. Lett. 2020, 11(10), 1799-1809. [pdf]
367. X. Xiao, Y. Kim, B. Romartinez-Alonso, K. Sirvydis, D. S. Ory, J. W. R. Schwabe, M. E. Jung, and P. Tontonoz,
"Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms,"
Proc. Natl. Acad. Sci. U. S. A. 2021, 118(2), e2024149118. [pdf]
368. X. Liu, A. Flores, L. Situ, W. Gu, H. Ding, H. Christofk, W. Lowry, and M. E. Jung, "Development of
Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss," J. Med. Chem. 2021, 64 (4), 2046-2063.
[pdf]
369. J. E. Gosschalk, C. Chang, C. K. Sue, S. D. Siegel, C. Wu, M. D. Kattke, S. W. Yi, R. Damoiseaux, M. E. Jung, H. Ton-That,
R. T. Clubb, "A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors," Sci. Rep. 2020, 10 (1), 8520.
[pdf]
370. H. J. Gim, J. Park, M. E. Jung, and K. N. Houk, "Conformational Dynamics of Androgen Receptors Bound to
Agonists and Antagonists," Sci. Rep. 2021, 11 (1), 15887. [pdf]
371. E. D. Micewicz, R. D. Damoiseaux, G. Deng, A. Gomez, K. S. Iwamoto, M. E. Jung, C. Nguyen, A. J. Norris,
J. A. Ratikan, P. Ruchala, J. W. Sayre, D. Schaue, J. P. Whitelegge, and W. H. McBride, "Classes of Drugs
that Mitigate Radiation Syndromes," Front. Phamacol. 2021, 12, article 666776. [pdf]
372. L. M. Urner, G. Y. Lee, J. W. Treacy, A. Turlik, S. I. Khan, K. N. Houk, and M. E. Jung, "Intramolecular NH···F Hydrogen Bonding
Interaction in a Series of 4-Anilino-5-Fluoroquinazolines: Experimental and Theoretical Characterization of Electronic and Conformational Effects,"
Chem. Eur. J. 2022, 28, e2021031. [pdf]
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